Abstract: Disclosed are a long-carbon-chain polyamide resin composition and a continuous fiber reinforced long-carbon-chain polyamide composite material. The long-carbon-chain polyamide resin composition includes the following components in parts by weight: 81.8-99.8 parts by mass of long-carbon-chain bio-based polyamide 5X resin, 0.2-1.6 parts by mass of an antioxidant, 0-0.8 parts by mass of a lubricant, 0-15 parts by mass of a compatibilizer, and 0-0.8 parts by mass of a coupling agent. The continuous fiber reinforced long-carbon-chain polyamide composite material prepared on the basis of the long-carbon-chain polyamide resin composition has high fiber content and good mechanical properties, is recyclable and can be used in fields of aerospace, military, automotive materials, sports equipment, building materials, electronic appliances, etc.

Abstract: Provided are a flame-retardant polyamide glass fiber composition and a preparation method therefor. The flame-retardant polyamide glass fiber comprising 40-65 parts by mass of a polyamide resin, 25-40 parts by mass of glass fibers, 0-20 parts by mass of a flame retardant, 0.2-1 part by mass of an antioxidant and 0.1-2 parts by mass of other auxiliaries. The flame-retardant polyamide glass fiber composition provided in the present disclosure not only has a bio-based source, but also has a flame-retardant of V-0 in UL94 and excellent mechanical properties, and can be widely applied to the fields of various engineering plastics with high requirements for flame retardant effect and dimensional stability.

Abstract: The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.

Abstract: Various embodiments of the present invention relate to plastic-metal junctions and methods of making the same. In various embodiments, the present invention provides a method of forming a junction between a metal form and a solid plastic. The method can include contacting a metal including a plurality of pores and a flowable resin composition including a polybutylene terephthalate and a polyethylene terephthalate. The method can also include curing the flowable composition to form the solid plastic, to provide the junction between the metal and the solid plastic.

Abstract: The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.

Abstract: The disclosure concerns thermoplastic resin compositions including a polymer resin, a dielectric glass fiber component, a hollow glass fiber, and an impact modifier.

Abstract: The disclosure relates to a thermoplastic blend comprising a polycarbonate, an inorganic filler, an impact modifier, and a heat stabilizer; and wherein a molded specimen of the thermoplastic blend exhibits an improved bonding strength, high melt flow rate, and high impact strength.

Abstract: The disclosure concerns thermoplastic resin compositions including a polymer resin, a dielectric glass fiber component, a hollow glass fiber, and an impact modifier.

Abstract: The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.

Abstract: In one aspect, the disclosure provides methods of distinguishing a glycosaminoglycan from one or more other components in a sample by subjecting the sample to size-exclusion chromatography using a mobile phase having a pH of 6.8 or lower. A mobile phase having a pH of 6.8 or lower is found to improve the separation of glycosaminoglycans from proteins during size exclusion chromatography. In some embodiments, improved separation is due to the low pH of the mobile phase causing elution of less dispersed fractions of the protein and/or glycosaminoglycan. In some embodiments, the overlap between protein and/or glycosaminoglycan fractions is reduced.

Abstract: In one aspect, the disclosure provides methods of distinguishing a glycosaminoglycan from one or more other components in a sample by subjecting the sample to size-exclusion chromatography using a mobile phase having a pH of 6.8 or lower. A mobile phase having a pH of 6.8 or lower is found to improve the separation of glycosaminoglycans from proteins during size exclusion chromatography. In some embodiments, improved separation is due to the low pH of the mobile phase causing elution of less dispersed fractions of the protein and/or glycosaminoglycan. In some embodiments, the overlap between protein and/or glycosaminoglycan fractions is reduced.

Abstract: Various embodiments of the present invention relate to plastic-metal junctions and methods of making the same. In various embodiments, the present invention provides a method of forming a junction between a metal form and a solid plastic. The method can include contacting a metal including a plurality of pores and a flowable resin composition including a polybutylene terephthalate and a polyethylene terephthalate. The method can also include curing the flowable composition to form the solid plastic, to provide the junction between the metal and the solid plastic.

Abstract: A polymer composition includes 15 to 60 wt %, preferably 20 to 56 wt % of a polycarbonate; 30 to 60 wt %, preferably 28 to 50 wt % of a poly(1,4-cyclohexanedimethylene terephthalate); 0.05 to 35 wt %, preferably 0.1 to 30 wt % of a poly(carbonate-siloxane); 0.5 to 18 wt %, preferably 1 to 13 wt % of a thermoplastic poly(ester-ether) copolymer, preferably comprising poly(butylene terephthalate) blocks and poly(oxyC1-C4 alkylene units); and 0.5 to 8 wt % of ethylene-alkyl (meth)acrylate copolymer, wherein alkyl is a C1-C4 straight chain, unsaturated hydrocarbon group; wherein the weight percentages are based on the total weight of the polymer composition. A method of manufacturing an article including the steps of melt blending the components of the polycarbonate composition is described. An article prepared by the method is also described.

Abstract: The present invention provides methods of inhibiting Raf kinase activity in a patient, the method comprising administering to the patient a compound having formula I: or a pharmaceutically acceptable salt thereof, wherein Rx, Ry, R1, L1, L2, Cy1, and Cy2 are as defined as set forth in the specification.

Abstract: The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.

Abstract: Electronics housings that include a thermoplastic composition are provided. The thermoplastic compositions include at least one polycarbonate, at least two polysiloxane-polycarbonate copolymers, and a flame retardant. The thermoplastic compositions can include an additional polycarbonate, an impact modifier, one or more additives, or any combination of these components. Methods used to prepare the thermoplastic compositions and electronics housings are also provided.

Abstract: A composition includes specific amounts of an aromatic polycarbonate, a block polycarbonate-polysiloxane, a poly(alkylene terephthalate), a block polyestercarbonate, and an organophosphate ester. Relative to a corresponding composition lacking the block polyestercarbonate, the composition exhibits improved solvent resistance while substantially maintaining impact strength, melt flow, and flame retardancy. The composition is useful for fabricating articles that may come into contact with liquid chemicals or chemical vapors.

Abstract: The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.

Abstract: The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.

Abstract: The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same.