Patents by Inventor Bing Shi

Bing Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250035420
    Abstract: A height measurement system includes: a first fixed assembly, configured to connect to an external fixing part so that the height measurement system is fixed on the external fixing part for use; a head plate, configured to move downwards from the first fixed assembly to the head of a user; a second fixed assembly, disposed on the head plate and being movable along with the heat plate; a digital tape measure, comprising a mounting assembly and a tape disposed in the mounting assembly, one of the mounting assembly and the tape head being attached to the first fixing assembly and the other to the second fixing assembly; a memory storing a standard height value of the first fixed assembly; and a data acquisition unit, configured to acquire a first tensile length of the tape when the head plate moves from the first fixed assembly to the user's head.
    Type: Application
    Filed: January 8, 2024
    Publication date: January 30, 2025
    Inventors: Mengying SHI, Bing LIANG, Guanglu YANG, Jinhua LAN, Jingkun ZHOU, Yue WU
  • Publication number: 20250034266
    Abstract: Described here is are antibodies to CCR8 having enhanced binding, ligand blocking and antibody dependent cellular cytotoxicity. Also described is are methods of treating a cancer by targeting tumor infiltrating lymphocytes in a cancer patient using a formulation comprising a CCR8 antibody described above.
    Type: Application
    Filed: December 2, 2022
    Publication date: January 30, 2025
    Inventors: Lishan KANG, Hongshui LIU, Lina WANG, Shang YIN, Shou LI, Bing WAN, Wenhua SHI, Min CHEN, Xinchuan DAI, David BELLOVIN, Jing ZHANG
  • Patent number: 12204528
    Abstract: A system receives a source database language statement according to a first dialect, determines a pattern of the source database language statement, the pattern comprising an abstract representation of the source database language statement, and checks whether the determined pattern is present in a cache of translations between patterns according to the first dialect and corresponding patterns according to a second dialect different from the first dialect. In response to the determined pattern being present in the cache of translations, the system converts, using a corresponding translation in the cache of translations, the source database language statement according to the first dialect to a respective target database language statement according to the second dialect.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: January 21, 2025
    Assignee: Micro Focus LLC
    Inventors: Lei Shi, Qin Zhou, Bing Gu, Dong-Hui Zhu, Feng Yan, Wen Zou
  • Patent number: 12202849
    Abstract: The present invention relates to novel crystalline forms of salts and/or co-crystals of tenofovir alafenamide, the pharmaceutical formulations, and the therapeutic uses thereof in treating viral infections.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: January 21, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Chiajen Lai, Bing Shi, Robert G. Strickley
  • Publication number: 20250011352
    Abstract: The present disclosure relates to solid forms of compounds and pharmaceutical compositions thereof, which are useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus
    Type: Application
    Filed: May 30, 2024
    Publication date: January 9, 2025
    Inventors: Ekaterina V. Albert, Yisoo M. Hwang, Bing Shi
  • Publication number: 20240409575
    Abstract: The present disclosure generally describes methods of preparing 1?-cyano nucleosides, such as a compound of Formula (I). For example, the compound of Formula (I) can be prepared from a compound of Formula (II-a) in a flow reactor.
    Type: Application
    Filed: May 6, 2024
    Publication date: December 12, 2024
    Inventors: Pavel R. Badalov, Stacy Bremner, Matthew R. Chin, Detian Gao, Nolan Griggs, Lars V. Heumann, Chiajen Lai, Robert R. Milburn, Sankar Mohan, Sean T. Neville, Bing Shi, Andrew C. Stevens, Nicholas A.J. Uhlig, Tiago Vieira, Todd A. Wenderski
  • Publication number: 20240317746
    Abstract: Described herein are crystalline forms of 5-(((2R,3S)-1-((7-chloro-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)-2-methylazetidin-3-yl)oxy)-N-cyclopropylpicolinamide (Compound 1), or a pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: March 22, 2024
    Publication date: September 26, 2024
    Inventors: Jing Liu, Jayachandra P. Reddy, Bing Shi, Kathleen E. Navis
  • Publication number: 20240254104
    Abstract: The present disclosure relates to pharmaceutically acceptable salts, cocrystals, and crystalline forms thereof, of a compound which is N—((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2- ((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-TH-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.
    Type: Application
    Filed: October 24, 2023
    Publication date: August 1, 2024
    Inventor: Bing Shi
  • Publication number: 20240245669
    Abstract: The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N—((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3- (trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus.
    Type: Application
    Filed: October 24, 2023
    Publication date: July 25, 2024
    Inventors: Travis Lee Houston, Bing Shi
  • Publication number: 20240101533
    Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.
    Type: Application
    Filed: June 5, 2023
    Publication date: March 28, 2024
    Inventors: Kevin McCormack Allan, Amanda Lynn Vandehey, Gediminas Brizgys, Sachin Dhar, Ian James Doxsee, Alex Goldberg, Lars V. Heumann, Zilin Huang, Nathaniel Thomas Kadunce, Shahrokh Kazerani, Willard Lew, Vinh Xuan Ngo, Brian Michael O`Keefe, Trevor James Rainey, Benjamin James Roberts, Bing Shi, Dietrich P. Steinhuebel, Winston C. Tse, Anna Michelle Wagner, Xianghong Wang, Scott Alan Wolckenhauer, Chloe Yuyi Wong, Jennifer R. Zhang
  • Patent number: 11845739
    Abstract: The present disclosure relates to pharmaceutically acceptable salts, cocrystals, and crystalline forms thereof, of a compound which is N—((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yOpyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2- ((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: December 19, 2023
    Assignee: Gilead Sciences, Inc.
    Inventor: Bing Shi
  • Patent number: 11833143
    Abstract: The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N—((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfony)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)- 3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: December 5, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Travis Lee Houston, Bing Shi
  • Publication number: 20230322727
    Abstract: Disclosed are solid forms of a Cot (cancer Osaka thyroid) inhibitor and corresponding methods of preparation thereof, wherein the Cot inhibitor has the following formula:
    Type: Application
    Filed: April 10, 2023
    Publication date: October 12, 2023
    Inventors: Kassibla E. Dempah, Bing Shi, Ana F. Voica, Kevin S. Williamson
  • Publication number: 20230295214
    Abstract: The present disclosure generally describes methods of preparing 1?-cyano nucleosides, such as a compound of Formula (I). For example, the compound of Formula (I) can be prepared from a compound of Formula (II-a) in a flow reactor.
    Type: Application
    Filed: February 10, 2023
    Publication date: September 21, 2023
    Inventors: Pavel R. Badalov, Stacy Bremner, Matthew R. Chin, Detian Gao, Nolan Griggs, Lars V. Heumann, Chiajen Lai, Robert R. Milburn, Sankar Mohan, Sean T. Neville, Bing Shi, Andrew C. Stevens, Nicholas A.J. Uhlig, Tiago Vieira, Todd A. Wenderski
  • Patent number: 11655237
    Abstract: Disclosed are solid forms of a Cot (cancer Osaka thyroid) inhibitor and corresponding methods of preparation thereof, wherein the Cot inhibitor has the following formula:
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: May 23, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Kassibla E. Dempah, Bing Shi
  • Patent number: 11613553
    Abstract: The present disclosure generally describes methods of preparing 1?-cyano nucleosides, such as a compound of Formula (I). For example, the compound of Formula (I) can be prepared from a compound of Formula (II-a) in a flow reactor.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: March 28, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Pavel R. Badalov, Stacy Bremner, Matthew R. Chin, Detian Gao, Nolan Griggs, Lars V. Heumann, Chiajen Lai, Robert R. Milburn, Sankar Mohan, Sean T. Neville, Bing Shi, Andrew C. Stevens, Nicholas A. J. Uhlig, Tiago Vieira, Todd A. Wenderski
  • Publication number: 20230091736
    Abstract: The present invention relates to novel crystalline forms of salts and/or co-crystals of tenofovir alafenamide, the pharmaceutical formulations, and the therapeutic uses thereof in treating viral infections.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 23, 2023
    Inventors: Chiajen Lai, Bing Shi, Robert G. Strickley
  • Patent number: 11440928
    Abstract: The present invention relates to novel crystalline forms of salts and/or co-crystals of tenofovir alafenamide, the pharmaceutical formulations, and the therapeutic uses thereof in treating viral infections.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: September 13, 2022
    Assignee: Gilead Sciences, Inc.
    Inventors: Chiajen Lai, Bing Shi, Robert G. Strickley
  • Publication number: 20220251069
    Abstract: The present disclosure relates to pharmaceutically acceptable salts, cocrystals, and crystalline forms thereof, of a compound which is N—((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yOpyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2- ((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.
    Type: Application
    Filed: January 26, 2022
    Publication date: August 11, 2022
    Inventor: Bing Shi
  • Patent number: RE49445
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: March 7, 2023
    Assignee: Sierra Oncology, Inc.
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin