Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: Disclosed is a face detection method and apparatus, the method including detecting a candidate area from a target image using a first sliding window moving at an interval of a first step length and detecting a face area in the candidate area using a second sliding window moving at an interval of a second step length less than the first step length.

Abstract: The touch panel includes a transparent substrate, a first touch-sensing electrode structure, a second touch-sensing electrode structure, and a patterned metal layer. The transparent substrate has a touch-sensing region and a peripheral region adjacent to at least one edge of the touch-sensing region. The first touch-sensing electrode structure is disposed on the touch-sensing region of the transparent substrate. The second touch-sensing electrode structure is positioned over the touch-sensing region and is configured to form at least one capacitor with the first touch-sensing electrode structure. The patterned metal layer has a plurality of first through holes located in the peripheral region and is extended on a level the same as the first touch-sensing electrode structure or the second touch-sensing electrode structure.

Abstract: A multimodal endoscope apparatus includes optical components (couplers, collimators, mirrors, beam splitters, filters and the like) structured to work together to interact with a multimodal endoscope probe to provide at least two imaging modalities selected from fluorescence imaging, optical coherence tomography, and photoacoustic imaging. The multimodal endoscope probe includes a fiber optic imaging bundle including a multitude of optical fibers. In embodiments employing photoacoustic imaging, the multimodal endoscope probe further includes a polymer-Fabry-Perot interferometer. In some embodiments, a galvo scanner and fiber collimator are included and are together capable of directing light to a single optical fiber of the multitude optical fibers. The system is modular in some embodiments, allowing for switching of some components.

Abstract: Novel biocompatible nanoparticles preferably based on a calcium or gallium analogue of Prussian blue, or independently an analogue of magnesium, or aluminum were designed and synthesized to take advantage of their ability to penetrate the bacterial cell membrane of the invading pathogen in an animal such as a human in both Gram-positive bacteria (e.g. Staphylococcus aureus) and Gram-negative bacteria (e.g. Pseudomonas aeruginosa), and undergo selective ion exchange with intracellular iron to disrupt iron metabolism in such pathogenic bacteria for antibacterial applications.

Abstract: A smartphone endoscope system includes a smartphone with first and second imaging sensors, and an imaging optics attachment. The imaging optics attachment includes a first and second imaging apparatus, the first imaging apparatus including a first light source, a beam splitter, an objective lens, and a fiber optic imaging bundle, wherein the fiber optic imaging bundle delivers excitation light to a target which emits a fluorescence emission and a reflectance emission both collected by the fiber optic imaging bundle and transmitted to the first imaging sensor. The second imaging apparatus includes a second light source, a DRS source fiber delivering broadband light to the target which produces a diffuse reflectance emission, a DRS detection fiber, a collimator, a slit, and a transmission grating wherein the transmission grating diffracts diffuse reflectance emission and creates diffracted light which is transmitted to a second imaging sensor.

Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: An assembly line apparatus for the automatic application of different types of labels or cushions or glue (“stickers”) on a workpiece has a transportation device, a plurality of application devices, a central control device, and a first expansive cooperation device. The central control device has first and other communication ports which may each function in accordance with different protocols and standards. The central control device is electronically connected to the transportation device via the first communication port and electronically connected to the application devices via a second or further communication ports. The first expansive cooperation device generates first and second control signals to instruct, via the central control device, the transportation device to move or to stop and to the application devices to apply or not to apply certain stickers on a certain area of a workpiece.

Abstract: A virtual hint based data cache way prediction scheme, and applications thereof. In an embodiment, a processor retrieves data from a data cache based on a virtual hint value or an alias way prediction value and forwards the data to dependent instructions before a physical address for the data is available. After the physical address is available, the physical address is compared to a physical address tag value for the forwarded data to verify that the forwarded data is the correct data. If the forwarded data is the correct data, a hit signal is generated. If the forwarded data is not the correct data, a miss signal is generated. Any instructions that operate on incorrect data are invalidated and/or replayed.

Abstract: An ambient-light-sensing hole structure package and a method of manufacturing the same are provided. The ambient-light-sensing hole structure package includes a transparent cover, a decorative layer, a porous structure layer, and an optical adhesive. The transparent cover has a surface. The decorative layer is disposed on the surface and the decorative layer has an opening that exposes a portion of the surface. The porous structure layer is disposed on one side of the decorative layer and the porous structure layer covers the portion of the surface. The porous structure layer includes a plurality of through holes, and the through holes overlap with the opening. The optical adhesive is interposed between the decorative layer and the porous structure layer.

Abstract: A method and an electronic device for enhancing efficiency of searching for a region of interest in a virtual environment are provided. The virtual environment includes a visible scene and an invisible scene. A picture-in-picture (PIP) is displayed in the visible scene as a directional guidance or distance hint related to the region of interest in the invisible scene, thereby saving time and enhancing efficiency of searching for the region of interest.

Abstract: An illumination device including an upper casing, a transparent bottom casing, a light source module and a reflection layer is provided. The upper casing has a lower surface. The transparent bottom casing has an upper surface. The light source module is disposed on the lower surface of the upper casing. The reflection layer is extended between the upper surface of the transparent bottom casing and the lower surface of the upper casing for reflecting the light emitted by the light source module.

Abstract: A load/store unit for a processor, and applications thereof In an embodiment, the load/store unit includes a load/store queue configured to store information and data associated with a particular class of instructions. Data stored in the load/store queue can be bypassed to dependent instructions. When an instruction belonging to The particular class of instructions graduates and the instruction is associated with a cache miss, control logic causes a pointer to be stored in a load/store graduation buffer that points to an entry in the load/store queue associated with the instruction. The load/store graduation buffer ensures that graduated instructions access a shared resource of the load/store unit in program order.

Abstract: A method for computing trigonometric functions, performed by an ALU (Arithmetic Logic Unit) in coordination with an SFU (Special Function Unit), is introduced to contain at least the following steps. The ALU computes a remainder r and a reduction value x* corresponding to an input parameter x. The SFU computes an intermediate function f(x*) corresponding to the reduction value x*. The ALU computes a multiplication of the reduction value x* by the intermediate function f(x*) as the computation result of a trigonometric function.

Abstract: A method for implementing a virtual communication card is provided. The method is applied to a terminal device and includes: resolving a data file prestored locally to obtain communication card information carried in the data file; loading the data file when the data file is determined to be matched with communication card information to be used according to the communication card information; and activating the data file to be used as a virtual communication card when the data file is determined to be in an unregistered state. An apparatus for implementing a virtual communication card is further provided.

Abstract: The present invention relates to compounds of formula I: in which X1, X2, X3, Y1, Y2, Y3, R1, R2, R3a, R4a, R4b, R5a, R5b, R6a and R6b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: An equipment maintenance prediction system and an operation method for the equipment maintenance prediction system are provided. The operation method includes steps of: configuring the processor to configure the factor decision module to select one of a plurality of parameter types as a decision parameter type according to a key parameter type, wherein the decision parameter type and the key parameter type are most correlative; configuring the processor to configure the prediction module to generate a prediction model according to a part of a plurality of historical sensing values of the decision parameter type and formulate a maintenance alerting condition according to a part of a plurality of historical sensing values of the key parameter type; and configuring the processor to configure the maintenance alerting module to monitor and alert according to the maintenance alerting condition.

Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, Y3, R1, R2, R4a, R4b, R5a, R5b, R6a and R6b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: A method for treating a skin wound of a subject is described. The method includes contacting the skin wound with a therapeutically effective amount of a wound healing composition comprising glycoprotein nonmelanoma clone B (GPNMB) protein, an active peptide fragment thereof, a GPNMB analog, a GPNMB potentiating agent, or a combination thereof.