Patents by Inventor Birgit Bossenmaier

Birgit Bossenmaier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES SPECIFICALLY BINDING TO HER3
    Publication number: 20170096487
    Abstract: The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human HER3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human HER3. Detection of human HER3 is, e.g., possible in a tissue sample, even when such tissue sample is a formalin-fixed paraffin embedded tissue (FFPET) sample.
    Type: Application
    Filed: March 29, 2016
    Publication date: April 6, 2017
    Inventors: Monika Soukupova, Michael Schraeml, Birgit Bossenmaier, Patrick C. Roche, Michael Gerg, Sebastian Dziadek
  • Anti-HER3 antibodies and uses thereof
    Patent number: 9611331
    Abstract: The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: April 4, 2017
    Assignee: Roche Glycart AG
    Inventors: Birgit Bossenmaier, Nikolaos Dimoudis, Thomas Friess, Guy Georges, Irene Kolm, Hans-Willi Krell, Valeria Lifke, Ekkehard Moessner
  • COMBINATION THERAPY OF ANTI-HER3 ANTIBODIES
    Publication number: 20160159912
    Abstract: The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.
    Type: Application
    Filed: October 7, 2015
    Publication date: June 9, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Frieder Bauss, Birgit Bossenmaier, Thomas Friess, Christian Gerdes, Max Hasmann, Marlene Thomas, Martin Weisser
  • Humanized anti-CDCP1 antibodies
    Patent number: 9346886
    Abstract: The present invention relates to humanized antibodies against human CDCP1 (anti-CDCP1 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: May 24, 2016
    Assignee: Roche Glycart AG
    Inventors: Johannes Auer, Birgit Bossenmaier, Guy Georges, Alexander Lifke, Ekkehard Moessner, Gerhard Niederfellner
  • Method for determining the anti-tumor efficacy of monoclonal antibodies
    Patent number: 9339560
    Abstract: The present invention relates to a method for determining the anti-tumor efficacy of monoclonal antibodies in pre-clinical rodent testings and the use of said method for the reduction of side testings.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: May 17, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Valeria Lifke, Werner Scheuer
  • ANTI-HER3 ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3
    Publication number: 20160002338
    Abstract: The invention relates to specific anti-HER3 antibodies, that bind to the beta-hairpin of HER3, their preparation and use as medicament.
    Type: Application
    Filed: May 12, 2015
    Publication date: January 7, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Birgit Bossenmaier, Richard Buick, Michael Gerg, Frank Kroner, Gerhard Niederfellner, Carmen Peess, Michael Schraeml
  • HER1 ANTIGEN BINDING PROTEINS BINDING TO THE BETA-HAIRPIN OF HER1
    Publication number: 20160002346
    Abstract: The invention relates to anti-HER1 antigen binding proteins, e.g. anti-HER1 antibodies, that bind to the beta-hairpin of HER1, methods for selecting these antigen binding proteins, their preparation and use as medicament.
    Type: Application
    Filed: May 12, 2015
    Publication date: January 7, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Birgit Bossenmaier, Michael Gerg, Gerhard Niederfellner, Carmen Peess, Michael Schraeml
  • Combination therapy of anti-HER3 antibodies
    Patent number: 9180185
    Abstract: The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: November 10, 2015
    Assignee: Hoffman-La Roche Inc.
    Inventors: Frieder Bauss, Birgit Bossenmaier, Thomas Friess, Christian Gerdes, Max Hasmann, Marlene Thomas, Martin Weisser
  • ANTI-HER3 ANTIBODIES AND USES THEREOF
    Publication number: 20140377273
    Abstract: The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Birgit Bossenmaier, Nikolaos Dimoudis, Thomas Friess, Guy Georges, Irene Kolm, Hans-Willi Krell, Valeria Lifke, Ekkehard Moessner
  • ANTI-HER3 ANTIBODIES AND USES THEREOF
    Publication number: 20140377272
    Abstract: The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Birgit Bossenmaier, Nikolaos Dimoudis, Thomas Friess, Guy Georges, Irene Kolm, Hans-Willi Krell, Valeria Lifke, Ekkehard Moessner
  • Antibodies against CDCP1 for the treatment of cancer
    Patent number: 8883159
    Abstract: The present invention relates to antibodies against human CDCP1 binding to the same epitope as CUB4 (Deposition No. DSM ACC2551) for the treatment of cancer.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: November 11, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Birgit Bossenmaier, Georg Fertig, Hans-Willi Krell, Reiner Lammers, Alexander Lifke, Gerhard Niederfellner
  • Anti-HER3 antibodies and uses thereof
    Patent number: 8859737
    Abstract: The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: October 14, 2014
    Assignee: Roche Glycart AG
    Inventors: Birgit Bossenmaier, Nikolaos Dimoudis, Thomas Friess, Guy Georges, Irene Kolm, Hans-Willi Krell, Valeria Lifke, Ekkehard Moessner
  • COMBINATION THERAPY OF ANTI-HER3 ANTIBODIES
    Publication number: 20140227255
    Abstract: The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.
    Type: Application
    Filed: January 9, 2014
    Publication date: August 14, 2014
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Frieder Bauss, Birgit Bossenmaier, Thomas Friess, Christian Gerdes, Max Hasmann, Marlene Thomas, Martin Weisser
  • HER3 ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3
    Publication number: 20140186358
    Abstract: The invention relates to anti-HER3 antigen binding proteins, e.g. anti-HER3 antibodies, that bind to the beta-hairpin of HER3, methods for selecting these antigen binding proteins, their preparation and use as medicament.
    Type: Application
    Filed: November 6, 2013
    Publication date: July 3, 2014
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, David Casagolda Vallribera, Guy Georges, Michael Gerg, Gerhard Niederfellner, Christian Scholz, Michael Schraeml
  • ANTI-HER3/HER4 ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3 AND THE BETA-HAIRPIN OF HER4
    Publication number: 20140186354
    Abstract: The invention relates to anti-HER3/HER4 antigen binding proteins, e.g. anti-HER3/HER4 antibodies, that bind to the beta-hairpin of HER3 and the beta-hairpin of HER4, methods for selecting these antigen binding proteins, their preparation and use as medicament.
    Type: Application
    Filed: November 6, 2013
    Publication date: July 3, 2014
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Guy Georges, Michael Gerg, Gerhard Niederfellner, Christian Scholz, Michael Schraeml
  • Bispecific Anti ErbB3 / Anti cMet Antibodies
    Publication number: 20140135482
    Abstract: The present invention relates to bispecific antibodies against human ErbB-3 and against human c-Met, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Birgit Bossenmaier, Ulrich Brinkmann, Wilma Dormeyer, Eike Hoffmann, Christian Klein, Gerhard Niederfellner, Juergen Michael Schanzer, Jan Olaf Stracke, Claudio Sustmann, Pablo Umana
  • Humanized anti-CDCP1 antibodies
    Patent number: 8394928
    Abstract: The present invention relates to humanized antibodies against human CDCP1 (anti-CDCP1 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: March 12, 2013
    Assignee: Roche Glycart AG
    Inventors: Johannes Auer, Birgit Bossenmaier, Guy Georges, Alexander Lifke, Ekkehard Moessner, Gerhard Niederfellner
  • Antigen Binding Proteins
    Publication number: 20120237506
    Abstract: The present invention relates to antigen binding proteins comprising two Fc parts, methods for their production, pharmaceutical compositions containing said antigen binding proteins, and uses thereof.
    Type: Application
    Filed: February 27, 2012
    Publication date: September 20, 2012
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Hubert Kettenberger, Christian Klein, Klaus-Peter Kuenkele, Joerg-Thomas Regula, Wolfgang Schaefer, Manfred Schwaiger, Claudio Sustmann
  • Monovalent Antigen Binding Proteins
    Publication number: 20120237507
    Abstract: The present invention relates to monovalent antigen binding proteins with a CH1-CL domain exchange, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: February 27, 2012
    Publication date: September 20, 2012
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Hubert Kettenberger, Christian Klein, Klaus-Peter Kuenkele, Joerg-Thomas Regula, Wolfgang Schaefer, Manfred Schwaiger, Claudio Sustmann
  • ANTI-HER3 ANTIBODIES AND USES THEREOF
    Publication number: 20110171222
    Abstract: The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: December 17, 2010
    Publication date: July 14, 2011
    Inventors: Birgit Bossenmaier, Nikolaos Dimoudis, Thomas Friess, Guy Georges, Irene Kolm, Hans-Willi Krell, Valeria Lifke, Ekkehard Moessner