Abstract: The present invention relates to a pharmaceutical composition for the treatment of castration-resistant prostate cancer, comprising bruceantin and nanoparticles. Using the composition comprising bruceantin and nanoparticles according to an embodiment, it is possible to effectively treat castration-resistant prostate cancer by reducing the side effects of bruceantin and overcoming the poor solubility thereof.

Abstract: A brake apparatus for a vehicle includes a cylinder housing a piston, a caliper body disposed on the outer side of the cylinder and surrounding a portion of the cylinder, a driver coupled with the cylinder and generating driving force to move the piston, and a coupling member coupling the cylinder with the caliper body.

Abstract: A brake device includes a caliper body, a brake pad disposed at one side of the caliper body, and a pad propulsion unit seated in the caliper body to press one surface of the brake pad. The pad propulsion unit includes a conversion assembly configured to convert rotational movement into rectilinear movement, a balance bar rotatably connected to one side of the conversion assembly, and at least two pressurizers coupled to the balance bar and coming into contact with the one surface of the brake pad. The brake device evenly distributes pressure to one surface of the brake pad through the balance bar coupled to the plurality of pressurizers, thereby improving surface pressure of the brake pad.

Abstract: Disclosed are a resin composition for an insulating layer of a recyclable power cable, and a molded article using the resin composition, wherein the resin composition for an insulating layer of a power cable has excellent whitening resistance while satisfying excellent flexibility and electrical properties. The present invention provides a polypropylene resin composition for an insulating layer of a power cable, and a power cable using the polypropylene resin composition, wherein the polypropylene resin composition includes 70 parts by weight to 90 parts by weight of a propylene block copolymer in which ethylene-propylene rubber (EPR) is dispersed in a propylene-ethylene random copolymer, 5 parts by weight to 20 parts by weight of a polyolefin elastomer (POE), and 5 parts by weight to 20 parts by weight of high molecular weight atactic polypropylene (PP) having a weight average molecular weight of 100,000 g/mol or greater.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating attention deficit/hyperactivity disorder (ADHD), containing KDS2010 as an active ingredient, wherein it has been identified, in a Git1 gene-deficient hetero (+/?) mouse, that the amount of GABA is increased in the striatum of the brain, which is in charge of hyperactivity, and thus the mouse can be used as an animal model of ADHD, and it has been identified that inattention and hyperactivity are alleviated upon the administration of KDS2010 to the Git1 gene-deficient hetero (+/?) mouse, and thus KDS2010 is provided as an agent for treating ADHD.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating attention deficit/hyperactivity disorder (ADHD), including SNAP5114 as an active ingredient. A Git1 gene-deficient hetero (+/?) mouse, confirmed to have increased amount of GABA in the brain striatum that controls hyperactivity, can be used as an animal model of ADHD, and by confirming that hyperactivity is ameliorated by administering SNAP5114 to the Git1 gene-deficient hetero (+/?) mouse, SNAP5114 is provided as a therapeutic agent for ADHD.

Abstract: Disclosed is a brake device including a brake pad, a pad pusher connected to the brake pad to linearly move the brake pad, a caliper body having a cylinder space defined therein where the pad pusher is seated, and a pad carrier that guides protrusions on both side surfaces of the brake pad, wherein the pad carrier is connected to the caliper body, wherein the pad pusher includes a bolt screw that rotates with respect to an axis within the cylinder space, a movable nut connected to the bolt screw, and a piston connected to one end of the movable nut, wherein the movable nut moves along a direction of the cylinder space by the rotation of the bolt screw, wherein the piston has a cylindrical shape with a front surface and a rear surface open, and further includes a piston cover closing the front surface.

Abstract: A brake device includes a brake pad, a pad thruster connected to the brake pad to linearly move the brake pad, and a caliper body provided with a cylinder space allowing the pad thruster to be seated therein. The pad thruster may include a conversion assembly configured to convert rotational motion into rectilinear motion, and at least two pistons connected to one end of the conversion assembly. The conversion assembly is seated in the cylinder space, and the at least two pistons are positioned outside of the cylinder space.

Abstract: In a system for setting current capacity of a charging cable for supply of battery power from one electric vehicle to another electric vehicle, a discharge controller is provided in a supply vehicle to discharge a battery of the supply vehicle to supply battery power to a target vehicle. A charge controller is provided in the target vehicle to charge a battery of the target vehicle with battery power supplied from the supply vehicle. A charging cable part electrically connects the supply vehicle and the target vehicle. The discharge controller is configured to perform control so that a discharging current of the charging cable part is set by detecting an allowable charging current of the charging cable part connected to the supply vehicle and comparing the allowable charging current with a predetermined maximum current outputtable from the supply vehicle.

Abstract: A brake device includes a brake pad, a pad propulsion part connected to the brake pad and configured to move the brake pad linearly, and a caliper body including a cylinder part on which the pad propulsion parti is accommodated. The pad propulsion part includes a conversion assembly converting rotation motion into linear motion, and a piston connected to one end of the conversion assembly, the conversion assembly is accommodated inside the cylinder part, and the piston is located outside the cylinder part.

Abstract: A composition and method according to the present invention may be very effectively used to diagnose malignant gastric cancer and predict the prognosis of gastric cancer.

Abstract: The present invention relates to a method for prevention, alleviation, or treatment of cancer patients, especially epithelial mesenchymal transition (EMP)-subtype cancer patients. If PHGDH, SHMT and MTHFD2 inhibitors are co-administered to patients with cancer in which the expression level of a glutaminase (GLS) gene or a protein encoded thereby has increased, 1C metabolism is more effectively inhibited such that there is a synergistic effect on the inhibition of cancer cell proliferation in patients with refractory cancer that is difficult to treat because of recurrence, metastasis, and anticancer drug resistance, thereby enabling cancer to be very effectively treated. In addition, the expression level of the GLS gene or protein encoded thereby is measured so that information related to customized treatment methods from initial stages is provided to each patient and the success of treatment can be increased.

Abstract: A brake device includes a brake pad, a pad moving unit connected to the brake pad and configured to linearly move the brake pad, a caliper body having a cylindrical portion for the pad moving unit to be seated therein, and a motor-gear assembly connected to the pad moving unit and transmitting power of a motor. The pad moving unit includes a conversion assembly for converting a rotational motion into a linear motion, and a piston connected to one end of the conversion assembly. The piston is positioned outside the cylindrical portion. The motor-gear assembly is fixed with respect to the caliper body.

Abstract: A composition according to the present invention, when used alone, is capable of inhibiting the growth of anticancer drug-resistant cancer by overcoming anticancer drug resistance or enhancing anticancer drug sensitivity, and when co-administered with an anticancer drug, may be used very effectively for the prevention, alleviation or treatment of various cancers, especially anticancer drug-resistant cancer.

Abstract: A composition according to the present invention is capable of inhibiting the growth of cancer cells and cancer stem cells, and also is capable of very effectively inhibiting the metastasis of cancer cells to other tissues. Thus, the composition may be very effectively used not only for the prevention, amelioration or treatment of cancer, but also for the inhibition of cancer metastasis.

Abstract: A method of fabricating a semiconductor device comprises mounting a carrier substrate and a wafer on a wafer chuck of a wafer chuck apparatus, the carrier substrate and the wafer attached to each other, injecting air into an air member by selectively controlling at least one air injection pipe connected to the air member of the wafer chuck apparatus, tilting the wafer chuck to a predetermined angle in response to the air being injected into the air member, processing the wafer while the wafer chuck is tilted, determining whether to change a tilt angle of the wafer chuck or a position of the wafer, adjusting an amount of air injected into the air member according to a changed tilt angle of the wafer chuck or a changed position of the wafer, and processing the wafer after adjusting of the amount of air in the air member.

Abstract: A pelvic floor muscle exercise machine according to the present invention comprises: a waist belt fixed to a user's waist; a support belt fixed to the waist belt; and an insertion device provided on the support belt. The insertion device comprises: an insertion part inserted into and extracted from the user's vagina; a rod extending from the insertion portion, penetrated by the support belt so as to be slidable; and guiding the movement of the insertion part; and an elastic member supported by the rod, and providing elastic restoring force to the insertion part by elastically transforming in accordance with the relative movement of the insertion part with respect to the support belt.

Abstract: An embodiment charging power filtering method includes receiving a signal instructing whether or not a filtering request is required from an on-board charger, selecting a mode of a plurality of modes for driving a filter based on the signal instructing whether or not the filtering request is required, and charging a battery using the selected mode.

Abstract: An embodiment system includes a mobile charger and a vehicle. The vehicle includes a connection port designed to interface with the mobile charger and a vehicle battery. A vehicle battery management unit is configured to control a current and a voltage of charging and output by detecting a temperature, a current, and a voltage in each module of the vehicle battery. A power conversion unit includes a motor and an inverter and is configured to convert a voltage received at the connection port to a magnitude of voltage that charges the vehicle battery. A charging management unit is coupled to the second battery management unit and the power conversion unit.

Abstract: Disclosed is a brake device, including a motor unit operated by an electrical signal, a gear unit having a plurality of gears connected to the motor unit, a cylinder unit having a piston connected to the gear unit to be propelled by operations of a plurality of the gears, a brake pad unit connected to the piston to be propelled by propulsion of the piston, and a caliper body having the cylinder unit seated thereon to guide the brake pad unit. Disclosed is a vehicle having a brake device, the brake device including a motor unit operated by an electrical signal, a gear unit having a plurality of gears connected to the motor unit, a cylinder unit having a piston connected to the gear unit to be propelled by operations of a plurality of the gears, a brake pad unit connected to the piston to be propelled by propulsion of the piston, and a caliper body having the cylinder unit seated thereon to guide the brake pad unit.