Abstract: A segmental precast composite-material composite-slab composite beam and a construction method thereof are provided, relating to the technical field of bridge design and construction. The segmental precast composite-material composite-slab composite beam mainly includes a segmental precast orthotropic composite top slab, a web, a bottom slab, and a wet joint between segments. The orthotropic composite top slab is composed of an orthotropic slab and an ultra-high-performance concrete layer (UHPC), and the interface connection of the orthotropic slab and the UHPC structural layer is achieved by a shear key. The UHPC structural layer is superposed with the orthotropic slab in segments in a precast plant to form a composite-slab composite beam segment to be entirely transported, hoisted and assembled, and the connection of the UHPC structural layers between the segments is achieved by casting a transverse wet joint in place.

Abstract: Embodiments of the present disclosure relate to a method, system and computer program product for trace data protection. In some embodiments, a method is disclosed. According to the method, a target task is determined from a plurality of tasks, where trace data of the target task is to be protected. The trace data of the target task is transferred from a first area to a second area of a memory. Existing trace data in the second area is offloaded to a storage device before being overwritten. In other embodiments, a system and a computer program product are disclosed.

Abstract: An automatic locking device for assembling a part to a workpiece is provided. The device includes a feeding mechanism, a fixture mechanism, a loading and unloading mechanism, a lifting mechanism, a rotating mechanism, and a locking mechanism. The feeding mechanism feeds the part to the fixture mechanism. The loading and unloading mechanism places the workpiece on the part. The lifting mechanism lifts up the fixture mechanism together with the part and the workpiece. The rotating mechanism rotates the fixture mechanism. The locking mechanism locks the part to the workpiece after the part and the workpiece are rotated by the rotating mechanism. The automatic locking device integrates multiple functions in a single station, reduces the number of the work stations and operatives, lowers the cost, and improves accuracy of the assembly. An assembling apparatus including the automatic locking device is also provided.

Abstract: Down-regulating autoimmune regulator (AIRE) function in B cells to produce antibodies is described. The antibodies can be class-switched, high affinity, and neutralizing, and have a high degree of somatic hypermutations, even in the framework region, as compared to antibodies produced in the absence of AIRE downregulation.

Abstract: A method for the construction of composite under-reamed pile, including: implementing a jet grouting and agitation at a pre-designed position to form a composite cemented-soil foundation; constructing the pile hole with a drilling rig, during which bulb cavities are formed when the pile structure includes bulbs; cleaning the pile hole, lifting down a reinforcing cage, lowering a concrete pouring conduit to the pile hole, and lifting the pouring conduit while pouring the concrete; the hardened concrete becoming a pile stem in the pile hole and a bulb in the bulb cavity. Thus, this construction method can completely eliminate the hole collapse risk at the bulb cavity position during drilling; the combined structure of the bulb and the composite cemented-soil foundation can greatly improve the bearing capacity of pile foundation, significantly reduce the settlement risk and the cost of the pile foundation, as well as shorten construction period.

Abstract: Provided are a determination method and apparatus of a main shaft bearing state, an electronic device, and a storage medium. The method includes the following steps: Bearing swing data of a target main shaft bearing at multiple moments within a preset time period are acquired; at least one current data period and current-period bearing swing data in each current data period are determined according to the multiple pieces of bearing swing data; a first abrupt change value and a second abrupt change value are determined according to the current-period bearing swing data in each current data period; and a main shaft bearing state of the target main shaft bearing is determined according to the first abrupt change value and the second abrupt change value.

Abstract: A test device suitable for acceleratory oblique water entry of a wedge has a frame, a water tank placed below the frame, an accelerator installed above the frame, an obliquing device connected to the frame, a wedge connected to the obliuqing device and an observation system. The frame is provided with vertical slide rails and a transverse slide rail. The accelerator mainly includes an air cylinder and an air compressor. The wedge is a flexible wedge or a rigid wedge. The observation system includes a pressure sensor, a strain sensor, a velocity sensor, an acceleration sensor and a particle image velocimetry device. The repeatability of the test process can be ensured by controlling the output pressure of the air cylinder.

Abstract: An automatic locking device for assembling a part to a workpiece is provided. The device includes a feeding mechanism, a fixture mechanism, a loading and unloading mechanism, a lifting mechanism, a rotating mechanism, and a locking mechanism. The feeding mechanism feeds the part to the fixture mechanism. The loading and unloading mechanism places the workpiece on the part. The lifting mechanism lifts up the fixture mechanism together with the part and the workpiece. The rotating mechanism rotates the fixture mechanism. The locking mechanism locks the part to the workpiece after the part and the workpiece are rotated by the rotating mechanism. The automatic locking device integrates multiple functions in a single station, reduces the number of the work stations and operatives, lowers the cost, and improves accuracy of the assembly. An assembling apparatus including the automatic locking device is also provided.

Abstract: Down-regulating autoimmune regulator (AIRE) function in B cells to produce antibodies is described. The antibodies can be class-switched, high affinity, and neutralizing, and have a high degree of somatic hypermutations, even in the framework region, as compared to antibodies produced in the absence of AIRE downregulation.

Abstract: Down-regulating autoimmune regulator (AIRE) function in B cells to produce antibodies is described. The antibodies can be class-switched, high affinity, and neutralizing, and have a high degree of somatic hypermutations, even in the framework region, as compared to antibodies produced in the absence of AIRE downregulation.