Patents by Inventor Bo Pi

Bo Pi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUANTITATIVE DIAGNOSTIC METHODS USING MULTIPLE PARAMETERS
    Publication number: 20120289422
    Abstract: Materials and Methods related to diagnosing a clinical condition in a subject, or determining the subject's predisposition to develop the clinical condition, using a multi-parameter system to measure a plurality of parameters and an algorithm to determine a disease score.
    Type: Application
    Filed: April 13, 2012
    Publication date: November 15, 2012
    Inventors: Yiwu He, Bo Pi, John Bilello
  • BIOMARKERS FOR MONITORING TREATMENT OF NEUROPSYCHIATRIC DISEASES
    Publication number: 20120178118
    Abstract: Methods for identifying and measuring pharmacodynamic biomarkers of neuropsychiatric disease, and for monitoring a subject's response to treatment.
    Type: Application
    Filed: December 6, 2011
    Publication date: July 12, 2012
    Inventors: Bo Pi, John Bilello
  • Quantitative diagnostic methods using multiple parameters
    Patent number: 8158374
    Abstract: Materials and Methods related to diagnosing a clinical condition in a subject, or determining the subject's predisposition to develop the clinical condition, using a multi-parameter system to measure a plurality of parameters and an algorithm to determine a disease score.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: April 17, 2012
    Assignee: Ridge Diagnostics, Inc.
    Inventors: Yiwu He, Bo Pi, John Bilello
  • INFLAMMATORY BIOMARKERS FOR MONITORING DEPRESSIVE DISORDERS
    Publication number: 20110269633
    Abstract: Materials and Methods related to developing a unipolar depression (MDD) disease score in a subject using a multi-parameter system to measure a plurality of parameters, and an algorithm to calculate a score.
    Type: Application
    Filed: March 11, 2009
    Publication date: November 3, 2011
    Inventors: John Bilello, Yiwu He, Bo Pi
  • DIAGNOSING AND MONITORING DEPRESSION DISORDERS BASED ON MULTIPLE SERUM BIOMARKER PANELS
    Publication number: 20110245092
    Abstract: Materials and Methods related to developing a unipolar depression (MDD) disease score in a subject using a multi-parameter system to measure a plurality of parameters, and an algorithm to calculate a score.
    Type: Application
    Filed: March 4, 2009
    Publication date: October 6, 2011
    Inventors: John Bilello, Yiwu He, Bo Pi
  • Multiple Biomarker Panels to Stratify Disease Severity and Monitor Treatment of Depression
    Publication number: 20110213219
    Abstract: Materials and Methods for stratifying disease severity and for monitoring major depressive disorder are provided.
    Type: Application
    Filed: January 26, 2011
    Publication date: September 1, 2011
    Applicant: RIDGE DIAGNOSTICS, INC.
    Inventors: John Bilello, Bo Pi
  • BIOMARKERS FOR MONITORING TREATMENT OF NEUROPSYCHIATRIC DISEASES
    Publication number: 20100280562
    Abstract: Methods for identifying and measuring pharmacodynamic biomarkers of neuropsychiatric disease, and for monitoring a subject's response to treatment. For example, materials and methods for monitoring the effectiveness of vagus nerve stimulation in a subject having a neuropsychiatric disease are provided.
    Type: Application
    Filed: April 6, 2010
    Publication date: November 4, 2010
    Applicant: RIDGE DIAGNOSTICS, INC.
    Inventors: Bo Pi, John Bilello
  • BIOMARKERS FOR MONITORING TREATMENT OF NEUROPSYCHIATRIC DISEASES
    Publication number: 20100280760
    Abstract: Methods for identifying and measuring pharmacodynamic biomarkers of neuropsychiatric disease, and for monitoring a subject's response to treatment. For example, materials and methods for monitoring the effectiveness of transcranial magnetic stimulation in a subject having a neuropsychiatric disease are provided.
    Type: Application
    Filed: April 1, 2010
    Publication date: November 4, 2010
    Applicant: Ridge Diagnostics, Inc.
    Inventors: Bo Pi, John Bilello
  • Optical Molecular Detection
    Publication number: 20100144052
    Abstract: Optical detection of molecules using a biochip having at least one reagent immobilizing area designed to receive one or more reagents and at least one calibration structure with a predetermined height to provide a height reference for optical measurement is disclosed. When the calibration structure is illuminated by a probe beam of light, a first reflected beam of light is reflected off the calibration structure, and a second reflected beam of light is reflected off the reagent immobilizing area. The first reflected beam and the second reflected beam are compared to determine a height at the reagent immobilizing area.
    Type: Application
    Filed: December 11, 2006
    Publication date: June 10, 2010
    Inventor: Bo Pi
  • METABOLIC SYNDROME AND HPA AXIS BIOMARKERS FOR MAJOR DEPRESSIVE DISORDER
    Publication number: 20100136700
    Abstract: Materials and methods for using combinations of metabolic syndrome and HPA axis biomarkers for monitoring major depressive disorder.
    Type: Application
    Filed: November 18, 2009
    Publication date: June 3, 2010
    Inventors: John Bilello, Bo Pi
  • HUMAN BIOMARKER HYPERMAPPING FOR DEPRESSIVE DISORDERS
    Publication number: 20100100333
    Abstract: Materials and Methods related to diagnosing depression disorders, or determining a subject's predisposition to develop a depression disorder, using a multi-parameter hypermapping system and algorithms related thereto.
    Type: Application
    Filed: October 15, 2009
    Publication date: April 22, 2010
    Applicant: RIDGE DIAGNOSTICS, INC.
    Inventors: Bo Pi, John Bilello
  • Reflection-mode fiber sensing devices
    Publication number: 20070098323
    Abstract: Fiber sensors formed on side-polished fiber coupling ports based on evanescent coupling are described. Such sensors may be configured to measure various materials and may be used to form multi-phase sensing devices. A Bragg grating may be implemented in such sensors to form reflective fiber sensors.
    Type: Application
    Filed: April 11, 2006
    Publication date: May 3, 2007
    Inventors: Bo Pi, Wei-Cheng Lin, Zhihao Chen
  • Optical multiphase flow sensor
    Patent number: 7087887
    Abstract: Waveguide sensors having a side-polished coupling port at the waveguide cladding to sense a material based on material-specific optical attenuation by evanescent coupling at the coupling port.
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: August 8, 2006
    Assignee: IFOS, Inc.
    Inventors: Bo Pi, Shulai Zhao, Zhihao Chen
  • Optical devices having WGM cavity coupled to side-polished port
    Patent number: 7085452
    Abstract: Optical devices having at least one whispering gallery mode cavity formed on a side-polished coupling port of a fiber or waveguide based on evanescent coupling are described.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: August 1, 2006
    Assignee: I FOS, Inc.
    Inventors: Wei-Cheng Wilson Lin, Bo Pi
  • Sensing devices based on evanescent optical coupling
    Patent number: 7068868
    Abstract: Fiber sensors formed on side-polished fiber coupling ports based on evanescent coupling. Such sensors may be configured to measure various materials and may be used to form multi-phase sensing devices.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: June 27, 2006
    Assignee: IFOS, Inc.
    Inventors: Bo Pi, Wei-Cheng Wilson Lin, Zhihao Chen, Shulai Zhao
  • Reflection-mode fiber sensing devices
    Patent number: 7060964
    Abstract: Fiber sensors formed on side-polished fiber coupling ports based on evanescent coupling are described. Such sensors may be configured to measure various materials and may be used to form multi-phase sensing devices. A Bragg grating may be implemented in such sensors to form reflective fiber sensors.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: June 13, 2006
    Assignee: IFOS, Inc.
    Inventors: Bo Pi, Wei-Cheng Wilson Lin, Zhihao Chen
  • Adjustable fiber optical filters
    Patent number: 6912343
    Abstract: Adjustable filters formed in fibers or waveguides based on evanescent coupling, where a coupling layer is formed between a waveguide overlay and a side-polished coupling port on the fiber or waveguide. A control mechanism may be provided to adjust a property of at least one of the waveguide overlay and the coupling layer to adjust the output of the filter.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: June 28, 2005
    Assignee: Oluma, Inc.
    Inventors: Zhihao Chen, Zheng Chen, Bo Pi
  • Fiber tap monitor based on evanescent coupling
    Patent number: 6744948
    Abstract: Fiber tap monitors formed on side-polished fiber coupling ports based on evanescent coupling.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: June 1, 2004
    Assignee: Oluma, Inc.
    Inventors: Bo Pi, Shulai Zhao, Zheng Chen, Robert Morse, Jian Li
  • Fiber devices having side evanescent coupling port
    Patent number: 6690857
    Abstract: Fiber optical devices formed on substrates fabricated with grooves that operate based on evanescent optical coupling through a side-polished fiber surface in each fiber involved.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: February 10, 2004
    Assignee: Oluma, Inc.
    Inventors: Shulai Zhao, Bo Pi
  • FIBER DEVICES HAVING SIDE EVANESCENT COUPLING PORT
    Publication number: 20040008935
    Abstract: Fiber optical devices formed on substrates fabricated with grooves that operate based on evanescent optical coupling through a side-polished fiber surface in each fiber involved.
    Type: Application
    Filed: December 3, 2002
    Publication date: January 15, 2004
    Applicant: Oluma, Inc., a Delaware corporation
    Inventors: Shulai Zhao, Bo Pi