Abstract: Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic methods, such as in imaging KDR-containing tissue and in the evaluation and treatment of angiogenic processes associated with neoplastic conditions. The present invention also provides processes for the large scale production of highly pure dimeric and monomeric peptide phospholipid conjugates as well as precursor materials used to form the conjugates. The present invention further provides processes for the large scale production of highly pure peptide phospholipid conjugates which contain very low levels of TFA.

Abstract: The present application discloses a light-emitting apparatus having a light-emitting device and a wavelength conversion layer. The light-emitting device has a first top surface and a first side surface, and the wavelength conversion layer has a second top surface and a second side surface and covers the first top surface. A ratio of a distance between the first top surface to the second top surface and a distance between the first side surface and the second side surface is between 1.1˜1.3.

Abstract: Methods for modulating expression of a component of a cell, comprising contacting the cell with a nucleic acid comprising an miR-140 nucleic acid sequence in an amount sufficient to modulate the cellular component are provided. Overexpression of miR-140 inhibits cell proliferation in both U-2 OS (wt-p53) and HCT 116 (wt-p53) cell lines. Cells transfected with miR-140 are more resistant to chemotherapeutic agent methotrexate. mi-140 expression is related to HDAC4 protein expression. The claimed methods reduce the protein expression level of HDAC4 without degrading the target mRNA.

Abstract: A power adapter for a portable computer includes a pulse width modulation unit and an output shaping unit and further includes a first judgment module that judges whether the portable computer is in a first state according to state judging parameters, and compares an output voltage with a first preset voltage and a second preset voltage when judging that the portable computer is in the first state, and acquires a judging result, wherein the first preset voltage is greater than or equal to the second preset voltage. The power adapter can increase efficiency.

Abstract: The present invention provides a method of on-line rapid fluid density measurement using a piezoresistive micro-cantilever, the present invention can achieve on-line measurement without changing the existing device; more importantly, without acquiring the resonant frequency of the cantilever in fluid to be detected, thus remarkably reducing measurement time, and guaranteeing the real on-line rapid measurement. By using the method of the present invention, measurement of the density of fluid to be detected by a calibrated piezoresistive micro-cantilever may be achieved within seconds or even shorter.

Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.

Abstract: The present disclosure provides a method and device for use by a routing switch device. In response to a determination to switch the routing switch device to switch from a conventional mode to an OpenFlow mode the following operations are performed. Table items of a forwarding table in the conventional mode are converted to flow table items in the OpenFlow mode. The converted flow table items are stored in a flow table of the routing switch device. Processing a received data packet based, at least in part, on the converted flow table items stored in the flow table.

Abstract: The invention provide an one-button locking mechanism for toilet seat lid, which cooperates with a toilet stand and is used to secure the toilet seat lid on the toilet bowl. The toilet seat lid has a rotary mechanism mounted in two ends thereof to freely pivot the toilet seat lid relative to the toilet bowl. The locking mechanism comprises a sleeve, a left sliding seat, a right sliding seat, and a button and a return spring that drive the left and right sliding seats to move along the left direction and right direction of the toilet seat lid.

Abstract: Disclosed is a method for verifying Mobile Equipment (ME), which includes that: an Ad Hoc hotspot, after determining that the ME transmitting equipment information is legal equipment, transmits corresponding ME information generated according to the equipment information to operating company database equipment, and receives verification key information returned by the operating company database equipment; and the Ad Hoc hotspot, after receiving a key verification request from the ME, verifies the ME by utilizing the corresponding verification key information, notifies the ME that the ME passes the verification if the ME passes the verification, and establishes a connection with the ME. The disclosure also discloses devices and a system for verifying the ME.

Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.

Abstract: MicroRNAs (miRNAs) are a class of non-coding small RNA molecules that regulate gene expression at the post-transcriptional level by interacting with 3? untranslated regions (UTRs) of their target mRNAs. The invention relates to the application of miR-192 and miR-215. Both of these miRNAs impact cellular proliferation through the p53-miRNA circuit, and interact with dihydrofolate reductase (DHFR) and thymidylate synthase (TS). Particularly, upregulation of these miRNAs reduces cellular proliferation. The invention relates to this discovery. For example, inhibiting miR-192 and/or miR-215 sensitizes a neoplasm or a subject with a neoplasm to chemotherapeutic agents. Furthermore, measuring the levels of miR-192 and/or miR-215 provides one with information regarding whether the neoplasm or subject will respond to chemotherapeutic agents. Accordingly, the invention relates to composition and methods relating to the identification, characterization and modulation of the expression of miR-192 and miR-215.

Abstract: A control channel for routing management messages to or from an OpenFlow controller is separated from a reserved port within a data channel for routing unknown data packets to or from the OpenFlow controller. The port may be reserved by setting a reserved port flag. A packet routing table may include a table miss entry that indicates the unknown packets should be routed via the reserved port. By utilizing the reserved port to route unknown packets, the unknown packets do not traverse into the control channel, and the separation of the OpenFlow control channel from the OpenFlow data channel is enhanced.

Abstract: A nitride-based field effect transistor (FET) comprises a compositionally graded and polarization induced doped p-layer underlying at least one gate contact and a compositionally graded and doped n-channel underlying a source contact. The n-channel is converted from the p-layer to the n-channel by ion implementation, a buffer underlies the doped p-layer and the re-channel, and a drain underlies the buffer.

Abstract: A method for removing a high definition nanostructure in a partly free-standing layer, the layer, a sensor comprising said layer, a use of said sensor, and a method of detecting a species, and optional further characteristics thereof, using said sensor. The sensor and method are suited for detecting single ions, molecules, low concentrations thereof, and identifying sequences of base pairs, e.g., in a DNA-strand.

Abstract: Embodiments of the invention relate to switch mode transition and processing upon loss of controller communication. One embodiment includes losing a connection with a controller by a switch device, entering a particular mode by the switch device, transferring flow entries of the switch device to one or more tables, and notifying network application protocols that correspond to the transferred flow entries.

Abstract: A method is provided for constructing a three-dimensional hyperspectral image using compressive sensing. The method includes: configuring on/off state of each mirror in an array of micromirrors in accordance with a pattern; capturing image data of a scene from a first point of view using a first photodetector; and capturing image data of the scene from second point of view using a second photodetector, where second point of view differs from the first point of view. The steps are repeated to obtain a series of measurement samples, where the array of micromirrors is configured in accordance with a pattern that differs amongst each measurement samples. By choosing different photodetectors with different band gap nanomaterials, the first and second photodetectors detects photons in the electromagnetic spectrum. As a result, the three-dimensional image also carry the spectrum information of the scene.

Abstract: Compressive sensing based video rate imaging techniques are presented. Rather than scan the entire image, the imaging system only scans part of the topography of the sample as a compressed scan. After the data has been collected, an algorithm for image reconstruction is applied for recovering the image. Because compressive sensing is used, the imaging rate is increased from several minutes per frame to seconds per frame. Non-vector space control techniques are also presented. No-vector space control use image or compressive data as the input and feedback to generate a closed-loop motion control. Compressive sensing technique provides an efficient data reduction method to retain the essential information in the original image. The non-vector space control method can be used as motion control method with compressive feedback without or with noise.

Abstract: The present invention relates to an application of povidone iodine (PVP-I) in the preparation of a medicine treating premature ejaculation, wherein the medicine is the compound consisting of PVP-I and any other biologically compatible carrier, such as PVP-I disinfectant or Andoful PVP-I disinfectant. The beneficial effect is: by experiment, PVP-I is proved to be able to increase patients' ILET and have a significant therapeutic effect for those suffering premature ejaculation.

Abstract: MicroRNAs (miRNAs) are a class of non-coding small RNA molecules that regulate gene expression at the post-transcriptional level by interacting with 3? untranslated regions (UTRs) of their target mRNAs. The invention relates to the application of miR-192 and miR-215. Both of these miRNAs impact cellular proliferation through the p53-miRNA circuit, and interact with dihydrofolate reductase (DHFR) and thymidylate synthase (TS). Particularly, upregulation of these miRNAs reduces cellular proliferation. The invention relates to this discovery. For example, inhibiting miR-192 and/or miR-215 sensitizes a neoplasm or a subject with a neoplasm to chemotherapeutic agents. Furthermore, measuring the levels of miR-192 and/or miR-215 provides one with information regarding whether the neoplasm or subject will respond to chemotherapeutic agents. Accordingly, the invention relates to composition and methods relating to the identification, characterization and modulation of the expression of miR-192 and miR-215.

Abstract: A method for initializing a media includes: obtaining an access point corresponding to a media equipment in a network sharing model; performing a network connection with the media equipment via the access point, and sending paring information to the media equipment via the network connection; accessing to network environment corresponding to the paring information, and paring a control terminal equipment with the media equipment in the network environment. A system includes: an obtaining module, configured to obtain an access point corresponding to a media equipment in a network sharing model; an access processing module, configured to perform a network connection with the media equipment via the access point, and send paring information to the media equipment via the network connection; a paring module, configured to access to network environment corresponding to the paring information, and pair control terminal equipment with media equipment in the network environment.