Abstract: A lateral flow test device includes a test chamber having a detection aperture. The lateral flow test device also includes an optical detector configured to receive light from an assay test strip through the detection aperture when the assay test strip is provided in the test chamber. The test chamber is configured for manual feed of at least a portion of the assay test strip passed the detection aperture. The optical detector is configured to detect one or more tracking features associated with the assay test strip so as to determine when at least a test line on the assay test strip is detectable through the detection aperture.

Abstract: An optical module for reading a test region of an assay includes a near-infrared light source for illuminating the test region of the assay with light in a near-infrared spectrum. The optical module also includes an optical detector. The optical detector includes an optical input for receiving light emitted from the test region of the assay and an electrical output. The optical module further includes an electrical signal processor electrically coupled to the electrical output. The optical module additionally includes one or more optical filter arranged in front of the optical input of the optical detector.

Abstract: The present invention relates to chimeric bacteriophage lysins which can be used to sanitize surfaces, for the treatment of bacterial infections and/or for the selective treatment of body odor-causing bacteria. The invention also includes synergistic combinations, methods of treatment and isolated polynucleotides which encode the chimeric lysins.

Abstract: An optical detector (1) on an application specific integrated circuit (ASIC) comprises at least one photodiode (5) for receiving incident light and configured to provide at least one diode signal, a modulator (2) configured to provide an AC drive signal and to provide a reference signal associated with the AC drive signal; and a lock-in amplifier (6) configured to receive said at least one diode signal from said at least one photodiode (5) and to receive the reference signal from the modulator (2), and to determine at least one of a phase and an amplitude of said at least one diode signal using the reference signal.

Abstract: A CMOS-based chip having multiple sensing modalities that are able independently to detect multiple metabolites present in a sample. In particular, the chip provides multiple sensing modalities capable of performing detection within the same physical test volume, i.e. the chip can simultaneously detect a plurality of chemical reactions occurring in the test volume, where each chemical reaction yields a result that is independently detectable. The chip may comprise an optical sensor (e.g. photodiode) and a chemical sensor (e.g. pH sensor, embodied as an ISFET). With this technique, multiple metabolites may be measured in real time using a small scale point-of-care device.

Abstract: An optical module (100) for reading a test region of an assay. The optical module comprises: a first light source (101) for illuminating the test region of the assay; an optical detector (103), comprising an optical input for receiving light emitted from the test region and an electrical output; a substrate (104) for mounting the first light source (101) and the optical detector (103); and a housing (105) comprising: a first opening (106) for providing a first optical path from the first light source (101) to the test region (103); wherein the housing (105) and the substrate (104) enclose and positionally align the first source (101) and the optical detector (103) relative to the first opening (106). The housing (105) may comprise one or more legs (108), such as a flexible hook portion which secures the housing (105) to the substrate (104) with a snap-fit engagement, extending from a first and/or second outer surface of the housing (105) in a vertical direction.

Abstract: A drive system comprises a support structure for a guideway defining an X-Y array of tracks (22, 24) so that one or more carriages (10) can run along the tracks to any desired position. The carriages are intended to either carry a single robotic device or work together to carry a larger robotic device. The track is made up of an array of pegs (14) supported from a ceiling plane made up of an array of tiles (8) which provide for electrical connections to the carriages. Each peg carries a spool mounted between two horizontal flanges that cooperates with a rectangular sprocket connected to a base of a cuboid carriage housing. The carriages are driven by internal electric motors that are arranged to drive two pairs of omniwheels (90) on the ceiling plane while the carriage is supported and guided by means of its sprocket.

Abstract: A particle detector. The particle detector comprises one or more light sources, an optical sensor, and a controller. The one or more light sources are collectively operable to simultaneously produce at least two wavelength ranges of emitted light. The optical sensor is configured to sense light of the at least two wavelength ranges emitted by the one or more light sources and to distinguish each range. The controller is configured to detect particles based on the light sensed by the optical sensor.

Abstract: A drive system comprises a support structure for a guideway defining an X-Y array of tracks (22, 24) so that one or more carriages (10) can run along the tracks to any desired position. The carriages are intended to either carry a single robotic device or work together to carry a larger robotic device. The track is made up of an array of pegs (14) supported from a ceiling plane made up of an array of tiles (8) which provide for electrical connections to the carriages. Each peg carries a spool mounted between two horizontal flanges that cooperates with a rectangular sprocket connected to a base of a cuboid carriage housing. The carriages are driven by internal electric motors that are arranged to drive two pairs of omniwheels (90) on the ceiling plane while the carriage is supported and guided by means of its sprocket.

Abstract: A CMOS-based chip having multiple sensing modalities that are able independently to detect multiple metabolites present in a sample. In particular, the chip provides multiple sensing modalities capable of performing detection within the same physical test volume, i.e. the chip can simultaneously detect a plurality of chemical reactions occurring in the test volume, where each chemical reaction yields a result that is independently detectable. The chip may comprise an optical sensor (e.g. photodiode) and a chemical sensor (e.g. pH sensor, embodied as an ISFET). With this technique, multiple metabolites may be measured in real time using a small scale point-of-care device.

Abstract: A wireless power receiving system for an electric vehicle comprises an electric traction motor for providing mechanical energy for propelling the vehicle. The electric traction motor is operable as a generator to convert received mechanical energy into electrical energy. An inverter is connectable to receive input electric energy from the electric traction motor when the electric traction motor operates as a generator and is operative to output electric charging energy in response to the input electric energy. A battery is connectable to receive the electric charging energy from the inverter. A regenerative braking (RB) mechanical power transfer mechanism is connected to mechanically couple RB mechanical energy from a drivetrain of the electric vehicle to the electric traction motor. A MDC mechanical power transfer mechanism is connected to mechanically couple MDC mechanical energy from a magneto-dynamic coupling (MDC) wireless power receiver to the electric traction motor.

Abstract: The Micro electro-mechanical system (MEMS) utilizes thermal micro-actuators for lens barrel positioning in a camera module for smart device such as mobile phone. The micro actuators are radially extended from a lens barrel, wherein each of the micro actuators is bendable in response to thermal energy. A control unit includes a heater circuit operatively linked to the micro actuators to controllably apply the thermal energy to each of the micro actuators, wherein each of the micro actuators is bent correspondingly to move the lens barrel with respect to the base so as to control a 3-axis positioning of the lens barrel. The micro actuators are also operated independent of ambient temperature.

Abstract: Improvements and modifications are provided in the type of frustrated total internal reflection (TIR) systems described in U.S. Pat. Nos. 6,885,496; 6,891,658; 7,286,280; 7,760,417 and 8,040,591. The improvements and modifications include various methods to improve display operation of hemispherical beaded front plane TIR systems such as (a) inhibit or prevent the undesired non-uniform distribution and lateral migration of charged, electrophoretically mobile, TIR frustrating particles by encapsulating or tethering the particles to the beaded front plane surface; (b) inhibit or prevent the settling of the TIR frustrating particles such as modifying the viscosity of the low refractive index medium; and (c) inhibit or prevent the non-uniformity of the applied electric field during display operation such as using a conforming rear electrode.

Abstract: The Micro electro-mechanical system (MEMS) utilizes thermal micro-actuators for lens barrel positioning in a camera module for smart device such as mobile phone. The micro actuators are radially extended from a lens barrel, wherein each of the micro actuators is bendable in response to thermal energy. A control unit includes a heater circuit operatively linked to the micro actuators to controllably apply the thermal energy to each of the micro actuators, wherein each of the micro actuators is bent correspondingly to move the lens barrel with respect to the base so as to control a 3-axis positioning of the lens barrel. The micro actuators are also operated independent of ambient temperature.

Abstract: Improvements and modifications are provided in the type of frustrated total internal reflection (TIR) systems described in U.S. Pat. Nos. 6,885,496; 6,891,658; 7,286,280; 7,760,417 and 8,040,591. The improvements and modifications include various methods to improve display operation of hemispherical beaded front plane TIR systems such as (a) inhibit or prevent the undesired non-uniform distribution and lateral migration of charged, electrophoretically mobile, TIR frustrating particles by encapsulating or tethering the particles to the beaded front plane surface; (b) inhibit or prevent the settling of the TIR frustrating particles such as modifying the viscosity of the low refractive index medium; and (c) inhibit or prevent the non-uniformity of the applied electric field during display operation such as using a conforming rear electrode.

Abstract: Improvements and modifications are provided in the type of frustrated total internal reflection (TIR) systems described in U.S. Pat. Nos. 6,885,496; 6,891,658; 7,286,280; 7,760,417 and 8,040,591. The improvements and modifications include various methods to improve display operation of hemispherical beaded front plane TIR systems such as (a) inhibit or prevent the undesired non-uniform distribution and lateral migration of charged, electrophoretically mobile, TIR frustrating particles by encapsulating or tethering the particles to the beaded front plane surface; (b) inhibit or prevent the settling of the TIR frustrating particles such as modifying the viscosity of the low refractive index medium; and (c) inhibit or prevent the non-uniformity of the applied electric field during display operation such as using a conforming rear electrode.

Abstract: The present invention provides a package for an apparatus for non-invasively monitoring of blood flow of an object, a magnetic field sensing device, and a magnetic source positioning device.

Abstract: The present invention provides an apparatus and method for non-invasively sensing pulse rate and blood flow anomalies using a localized, uni-directional, and constant magnetic field. The apparatus comprises a magnetic source for producing the magnetic field, a signal acquisition module with a magnetic sensor for detecting the modulations of the magnetic field caused by the blood flow; and a signal processing module for processing the acquired signals so as to produce data of pulse rate and blood flow anomalies. The method senses pulse rate and blood flow anomalies by providing a localized, uni-directional, and constant magnetic field in proximity to a blood vessel; detecting the variations of the magnetic field caused by the flow of pulsatile blood within the blood vessel; and processing the signals of the detected variations so as to monitor the blood flow.

Abstract: The present invention provides a package for an apparatus for non-invasively monitoring of blood flow of an object, a magnetic field sensing device, and a magnetic source positioning device.

Abstract: The present invention provides an apparatus and method for non-invasively sensing pulse rate and blood flow anomalies using a localized, uni-directional, and constant magnetic field. The apparatus comprises a magnetic source for producing the magnetic field, a signal acquisition module with a magnetic sensor for detecting the modulations of the magnetic field caused by the blood flow; and a signal processing module for processing the acquired signals so as to produce data of pulse rate and blood flow anomalies. The method senses pulse rate and blood flow anomalies by providing a localized, uni-directional, and constant magnetic field in proximity to a blood vessel; detecting the variations of the magnetic field caused by the flow of pulsatile blood within the blood vessel; and processing the signals of the detected variations so as to monitor the blood flow.