Abstract: Some embodiments of devices, systems, and methods obtain at least one first image, wherein the at least one first image is defined in an image space; select at least one feature in the at least one first image; define a topology based on the at least one feature; generate a topology mapping between the topology and the image-space topology; obtain a plurality of anomaly scores, wherein each anomaly score of the plurality of anomaly scores was generated based on a respective detection area in a second image; map the plurality of anomaly scores to the topology based on the topology mapping; and normalize each anomaly score in the plurality of anomaly scores based on the respective neighboring anomaly scores in the topology, thereby generating normalized anomaly scores.

Abstract: Ladders and ladder components are provided including feet for ladders configured for securement of the ladder to a supporting surface, adjustable leg members for ladders, bearing members for ladders, and adjustment mechanisms for ladders. In one embodiment, an adjustment mechanism may include a first pair of spaced apart rails, a pair of adjustable legs having a first end hingedly coupled to one of a pair of adjustment mechanisms and a second end coupled with a foot. The adjustment mechanisms may be slidably coupled with the rails and in one embodiment, each adjustment mechanism is selectively displaceable along a length of its associated rail only when upward force is absent from the adjustment mechanism, the upward force being defined in a direction from a lower end of the associated rail towards the adjustment mechanism.

Abstract: The present invention relates to a method and system for determining Copy Number Variations (CNVs) in a genomic test sample including target amplicons and a reference amplicons. Specifically, nucleic acid melting curves are generated for the test sample. A mathematical model is fitted to each of the nucleic acid melting curves to separate target and reference melting reactions within the measured nucleic acid melting curve. The fitting parameters of the mathematical model are calculated. A CNV of the test sample is determined based on the fitting parameters of the mathematical model corresponding to the target and reference melting reactions.

Abstract: A system and method is disclosed for performing diagnostics on patient devices (720). The patient devices (720) may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server (710) may maintain a database of diagnostic data (718) indicating faults in one or more of a plurality of patient devices (720). The server (710) may transmit this diagnostic data (718) to one or more computing devices (760), including identification of faults that have occurred. The server (710) may also transmit service data to the plurality of patient devices (720) in order to address the identified faults.

Abstract: Some embodiments of devices, systems, and methods obtain at least one first image, wherein the at least one first image is defined in an image space; select at least one feature in the at least one first image; define a topology based on the at least one feature; generate a topology mapping between the topology and the image-space topology; obtain a plurality of anomaly scores, wherein each anomaly score of the plurality of anomaly scores was generated based on a respective detection area in a second image; map the plurality of anomaly scores to the topology based on the topology mapping; and normalize each anomaly score in the plurality of anomaly scores based on the respective neighboring anomaly scores in the topology, thereby generating normalized anomaly scores.

Abstract: Devices, systems, and methods obtain an image; perform at least one nonlinear locally-adaptive mapping on the image, thereby generating a revised image; generate an edge-enhanced image based on the revised image; and perform dynamic contrast stretching on the edge-enhanced image, thereby generating an enhanced image.

Abstract: Imaging methods aid a user in understanding relative depths of objects or topography within a field of view. In one method, image data is gathered using 3D image sensors, while illumination of an area of interest is alternated with projection of a pattern onto the area of interest. The captured image data is used to display a 3D true color image; a monochrome grid on surfaces of the area of interest; a 3D true color image with a monochrome grid on surfaces of the area of interest; a 2D or 3D false color image where different colors identify different depths of regions of the area of interest; and/or a 2D or 3D true color image of an area of interest with features in the area of interest located a first depth relative to the image sensors highlighted with a common color. In another method, 3D image data is used to generate a 2D image that highlights features at a common depth using the same color.

Abstract: Closed-loop melt pool size control for additive manufacturing is integrated with site-specific changes to a controller set-point. Site-specific control enables localized control of bead geometry and material properties in an additive manufacturing system, thus offering enhanced defect mitigation capabilities when compared with constant setpoint technologies. Trigger points, generated by the projection of a secondary geometry onto a primary geometry, mark locations of the volume of a part under manufacture where site-specific changes in setpoint occur. Through this technique, it is possible to manufacture a specific geometry that occurs beyond a predefined toolpath of a print head. Implications of this capability extend beyond localized control of bead geometry to potential mitigations of defects and functional grading of component properties.

Abstract: A monitor and control system for a hydraulic fracturing pump is described herein to reduce or eliminate harmful oscillations in fluid discharge pressure caused by the pump load dynamics. The monitor and control system receives various sensor data from the operation of the pump, including the pump crank position, and executes a pump control equation or model based on the pump sensor data, pump load data and/or pump speed data. Pump control equations or models are specific to the design and dynamic operation of the pump, incorporating the number of plungers, pump dynamics, motor lag and motor dynamics, etc. Using the pump control equations or models, the monitor and control system determines control commands for the pump motor to reduce or eliminate the oscillatory discharge pressure at the pump.

Abstract: A system and method for updating patient devices is disclosed. The patient devices may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server may maintain a database of configuration data indicating the versions of the software and firmware that is currently installed on the patient devices. The server may also transmit updated instructions from over a network, including a wireless network. Particular patient devices may be selected for updating based on the configuration data. Upon performing an update a patient device may transmit configuration data to the server.

Abstract: Embodiments of the invention disclosed herein include devices for sterilizing items, particularly hand-held writing implements, using ultraviolet radiation. Other useful features of the sterilizer embodiments include a no touch proximity sensor for opening the lid to access sterilization ports and any items within the ports, automatic descent of the items into the sterilizer and closure of the lid for a preselected sterilization cycle without the lid binding on the items in the ports.

Abstract: A system and method is disclosed for performing diagnostics on patient devices. The patient devices may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server may maintain a database of diagnostic data indicating faults in one or more of a plurality of patient devices. The server may transmit this diagnostic data to one or more computing devices, including identification of faults that have occurred. The server may also transmit service data to the plurality of patient devices in order to address the identified faults.

Abstract: An apparatus for automatically adjusting a collection of images based on their lighting conditions is provided. The apparatus obtains one or more images, determines a first lighting condition scores for each lighting condition and for each of the one or more images using a trained prediction model, and labels the each of the one or more images based on the determined first lighting condition scores.

Abstract: The present invention relates to methods for the analysis of nucleic acids present in biological samples, and more specifically to normalize a high resolution melt curve to assist in the identification of one or more properties of the nucleic acids. The present invention provides methods and systems that incorporate a background identification algorithm according to invention principles using raw melt curve data to identify reactions that are unrelated actual DNA melt reactions. Furthermore, a web-based application for analyzing experimental data is provided. The raw experimental data obtained from a variety of instruments is processed and analyzed on a server and presented to a user through a user interface (UI).

Abstract: Some embodiments of systems, devices, and methods obtain a plurality of training images; obtain one or more target regions; generate one or more respective statistical characterizations of the one or more target regions; obtain a test image; locate the one or more target regions on the test image; compare the one or more target regions in the test image to the one or more respective statistical characterizations of the one or more target regions; and detect anomalies in the one or more target regions in the test image based at least in part on the comparison of the one or more target regions in the test image to the one or more respective statistical characterizations of the one or more target regions.

Abstract: A method may include receiving an indication that a recalculation operation is to be completed for data stored in a data file; determining that a currently assigned number of threads for execution of the recalculation operation is lower than a target number of threads for the recalculation operation; requesting an additional thread for execution of the recalculation operation; beginning execution of the recalculation operation using the currently assigned number of threads; receiving an indication that the additional thread is available for execution of the recalculation operation; updating the currently assigned number of threads to include the additional thread; and continuing execution of the recalculation operation using the updated currently assigned number of threads.

Abstract: A system for monitoring contamination level of effluent of an offline brush conditioning system includes a first set of reservoirs configured to collect first effluents from corresponding portions of a first brush and a second set of reservoirs configured to collect second effluents from corresponding portions of a second brush, and the first and second effluents are from a fluid used to condition the first and second brushes that are configured to clean a surface of a semiconductor wafer. An effluent contamination monitor is configured to monitor contamination levels of the first and second effluents, wherein the monitored contamination levels may provide feedback for use in the brush conditioning.

Abstract: Devices, systems, and methods obtain a reference image; obtain a test image; globally align the test image to the reference image; select subfields in the test image; align the subfields in the test image with respective areas in the reference image; warp the test image based on the aligning of the subfields; select anchor points in the reference image; select anchor-edge points in the reference image; realign the subfields in the warped test image with respective areas in the reference image based on the anchor points in the reference image and on the anchor-edge points in the reference image; and warp the warped test image based on the realigning of the subfields.

Abstract: A spacing apparatus for creating a properly dimensioned gap during the installation of a flooring system, the spacing apparatus including a first element having a non-adjustable width (W) corresponding to an intended gap width, the first element extending in a first direction and joined to a projection element, the first direction and the projection element being generally perpendicular to each other, the projection element having a first portion having a non-adjustable width (T-1) corresponding to an intended gap width measured from a surface of the projection element in a direction parallel to the direction of the first element, the projection having a section portion having a non-adjustable width corresponding to a second intended expansion gap measured from a surface of the projection element in a direction parallel to the direction of the first element, wherein each of said intended gaps has a different width and wherein a gap is provided between a flooring plank and a vertical surface.

Abstract: A blow molded multilayer article with a hollow body and a wall being formed by at least three layers including a first skin layer, a second skin layer and a core sandwiched between the first and second skin layers. The skin layers can include a first thermoplastic material and an effect pigment and/or a porogen. The core can include recycled thermoplastic material and pigment and/or dye. The article can contain greater than 30% recycled thermoplastic material.