Abstract: Disclosed herein are compounds of the formulas: as well as analogs thereof, wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used to inhibit ROR? and/or reduce the expression of IL-17. Also provided are methods of administering compounds and composition provided herein to a patient in need thereof, for example, for the treatment or prevention of diseases or disorders associated with inflammation or autoimmune disorders.

Abstract: Various techniques for predictive replenishment of a sample of an item in accordance with an automatically adaptive schedule is described, including receiving at an adaptive distribution platform multiple requests for one or more items to be replenished by the adaptive distribution platform, analyzing each of the requests to identify an electronic request message associated with each of the requests and the items, identifying in the electronic request message an item characteristic associated with at least one item of the items to be replenished by the adaptive distribution platform, linking the item characteristic to a profile, and generating a control signal to a merchant computing system, the control signal including control data associated with replenishing the item and profile data.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and control systems to provide a platform to facilitate implementation of an interface, and, more specifically, to a computing and data storage platform that implements specialized logic to facilitate distribution of items in accordance with an automatically adaptive schedule, for example, via an interface. In some examples, a method may include predicting data representing, for example, a zone of time in which depletion of an item is predicted. The method may monitor whether to replenish the item, and transmit via a network an electronic message including one or more item characteristics associated with the item to be replenished. The method may also include receiving another electronic message, and transmitting a control message to a merchant computing system to initiate adaptive distribution to replenish the item, among other things.

Abstract: Systems and methods for lighting system lens heating are described. The systems and methods include a substantially clear thermoplastic substrate; and a conductive ink or film circuit on the thermoplastic substrate.

Abstract: A headlight system for a banking vehicle is provided. The headlight system includes a plurality of optical assemblies being arranged about an optical horizon and an optical vertical axis. Each of the plurality of optical assemblies includes an illumination source and an optical element. Each of the illumination sources is configured to direct light toward a corresponding one of the optical elements to produce an illumination region. The illumination regions combine to form an illumination pattern that includes at least one illumination region that is radial and is positioned relative an optical origin. The intersection between the optical horizon and the optical vertical axis defines the optical origin.

Abstract: Computer software that causes a stream processing management node to perform the following operations: (i) establishing data communication between the stream processing management node and a plurality of stream processing instances executing on respective computing environments in a multi-environment computing system; (ii) distributing one or more processing units of a stream processing job to a first set of stream processing instances of the plurality of stream processing instances; (iii) receiving, from the one or more stream processing instances of the first set of stream processing instances, processing results associated with the one or more processing units of the stream processing job; and (iv) performing a machine learning based stream management operation based, at least in part, on the received processing results.

Abstract: An air-boom spreader has a hopper for containing particulate material, a metering device having a plurality of sluices, a plurality of outlets transversely spaced-apart on a boom in a direction perpendicular to the direction of travel of the spreader, and a plurality of air lines connecting the plurality of sluices to the plurality of outlets for conveying the particulate material in an air stream from the plurality of sluices to the plurality of outlets. The spreader has more than twice as many outlets as sluices, and the plurality of outlets has an innermost outlet, an outermost outlet and at least three other outlets between the innermost outlet and the outermost outlet whereby each of the innermost outlet and the outermost outlet are supplied with half as much of the particulate material as each of the at least three other outlets.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and digital messaging and control systems to determine at an adaptive distribution platform using a distribution predictor a point of time associated with a scheduled delivery of an item coinciding substantially with a zone of time associated with a predicted distribution date of the item, to transmit to a device an electronic message having data associated with an item characteristic and other data associated with a control user input configured to adapt the scheduled delivery, to receive a response to the electronic message indicating one or more actions to manage an order associated with the item, to determine whether a replenishment adjustment of the item is requested, and to transmit a control signal to a merchant computing system to perform one or more data operations associated with the order.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and control systems to provide an interface, and, more specifically, to a computing and data storage platform that implements specialized logic to facilitate adaptive scheduling automatically to optimally distribute items, such as shipping an item in accordance with an adapted frequency for a subscription. In some examples, a method may include identifying item characteristics associated with an item, determining a frequency based on at least an item characteristic in association with a subset of subscriber accounts, generating data representing a frequency and a subset of the item characteristics to integrate with a web page generated for a merchant computing system, and transmitting the formatted data to a user interface to display a display portion based on the formatted data as an integrated portion of an integrated web page including the web page.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and control systems to provide a platform to facilitate implementation of an interface and one or more sensors, and, more specifically, to one or more sensors that implements specialized logic to facilitate in-situ monitoring of inventories of consumables and automatic reordering of a consumable. In some examples, a method may include receiving sensor data representing usage of a device configured to process a consumable, characterizing the usage to form a characterized value, correlating data representing a unit of the consumable processed via the device to a characterized value of the usage, adjusting an amount representing an inventory of the consumable, detecting an amount of the inventory of the consumable is associated with one or more ranges of threshold values, and generating data representing a request to replenish the inventory of the consumable.

Abstract: A bank angle of a vehicle can be accurately calculated using yaw axis data and roll axis data, and based on the calculated bank angle, vehicle illumination optics can be controlled to maintain a pattern of distributed light from the illumination optics to be generally horizontal. The calculated bank angle may be zeroed when the yaw axis data equals zero. The improved pattern of distributed light from the illumination optics illuminates a more natural field of view for the vehicle driver during a bank.

Abstract: Virality cause determination includes receiving a plurality of historical feedback items. It further includes bucketing a first feedback item in the plurality of historical feedback items into a first partition of feedback items, and bucketing a second feedback item in the plurality of historical feedback items into a second partition of feedback items. The second partition of feedback items is a baseline partition of feedback items. It further includes determining a set of candidate patterns present in the first partition of feedback items. It further includes determining whether a candidate pattern in the set of candidate patterns is disproportionately associated with the first partition of feedback items relative to the baseline partition of feedback items.

Abstract: A computer system is provided for protecting access to one or more hardware devices with a hardware device password that is invisible to a user, the system comprising a mobile device and the hardware device, the mobile device including: a memory, the memory storing one or more invisible passwords; an application in the memory; a wireless interface for communicating with the hardware device; and a processor coupled to the memory, the application and the wireless interface, the hardware device including: a memory; a wireless interface for communicating with the mobile device; and a processor coupled to the memory and the wireless interface; wherein the processor in the mobile device is configured to receive a hardware device identifier from the processor in the hardware device; wherein the application in the mobile device is configured to select, based upon the hardware device identifier, the invisible password for the hardware device; and the processor in the hardware device is configured to authenticate the a

Abstract: Disclosed is a skateboard grinding device configured to install within a skateboard wheel for facilitating grinding of the skateboard on an object.

Abstract: Embodiments of the present disclosure relate to real-time digitally signing of a virtual object. The real-time digital signing of a virtual object is provided in a multi-user real-time context between signor and signee that enables the signor to perform the real-time digital signing and the signee to visually experience the real-time signing. The real-time digital signing may be provided to the signor and signee in parallel, and/or one or more additional viewers taking part in the digital signing. Upon completion of the digital signing, some embodiments in near-real-time generate a digital asset that is linked to the virtual object modified with the digital signature, which may be assigned to and/or otherwise linked with the signee for subsequent retrieval and/or use.

Abstract: A light assembly and method for steering a vehicle headlight illumination pattern. In one aspect, a method includes providing a processor programmed to perform the steps of: illuminating a subset of consecutive LEDs in the line including LEDs associated with the first and second edge illumination fields; as the direction of the vehicle wheels changes: (i) fading the LED associated with one of the first and second illumination fields off while simultaneously fading the LED associated with the other of the first and second illumination fields on thereby changing the illumination pattern; and (ii) repeating step (i) so that the illumination pattern tracks the direction of the vehicle wheels.

Abstract: Impact-based strength and weakness determination includes receiving a plurality of industry-wide feedback items, the industry-wide feedback items pertaining to a plurality of entities associated with an industry. It further includes, based at least in part on an evaluation of the plurality of industry-wide feedback items, generating an industry-wide reputation scoring model usable to determine an expected reputation score for a typical entity in the industry based at least in part on a combination of one or more reputation score components. Generating the industry-wide reputation scoring model comprises determining (1) a baseline reputation score, and (2) an expected impact of a reputation score component on reputation scoring for the typical entity in the industry.

Abstract: A devices for coupling or mounting machine elements with a minimized coefficient of friction, as well as methods of minimizing the coefficient of friction in said devices are described herein. The device includes reciprocal inclined surfaces with a liner for minimizing friction therebetween. The liner, or liners, include an anti-friction fabric for reducing friction between the inclined surfaces.