Abstract: A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Abstract: A clot retrieval device with an elongate shaft and an expandable section, the expandable section having a framework of interconnected strut elements distal of the elongate shaft, the strut elements forming an outer expandable body and an inner expandable body. At least a portion of the strut elements include a first coating of radiopaque material defining a plurality of micro-columns, wherein each micro-column includes a length extending between a first end coupled to one of the plurality of strut elements and a second free end opposite the first end, the length of each micro-column is longer than a width of each micro-column. The second free end is capable of moving further apart when a convex bend is applied to the respective strut element during use. Also including a second coating.

Abstract: A clot retrieval device comprising an elongate shaft having a proximal end and a distal end and a clot retrieval element at the distal end of the elongate shaft. A proximal end of the elongate shaft of the clot retrieval device is adapted for retraction of a first catheter over the clot retrieval device elongate shaft. A second catheter is advanced to or adjacent to the distal end of the clot retrieval device shaft to enable enhanced aspiration adjacent to the clot retrieval element.

Abstract: A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24, 49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24, 49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Abstract: A clot retrieval device may include an elongate shaft and an expandable section. The expandable section may include a framework of interconnected strut elements. The connection region between adjacent strut elements may include crown elements. Additionally, the framework may be formed from a substrate material and at least a portion of a plurality of said strut elements may be coated with a coating material. Further, at least a portion of a plurality of said crown elements may not be coated with said coating material.

Abstract: A clot removal device for removing clot from a body vessel comprising an expandable structure and an elongate member. The elongate member can have a proximal end and a distal end, the elongate member being connected to the expandable structure at its distal end. The expandable structure can have a constrained delivery configuration, an expanded clot engaging deployed configuration, and an at least partially constrained clot pinching configuration. At least a portion of the expandable structure can be configured to engage clot in the expanded deployed configuration and to pinch clot on movement from the deployed configuration to the clot pinching configuration.

Abstract: A clot retrieval system comprises an elongate member having a proximal end and a distal end, and a clot engaging element at the distal end of the elongate member the clot engaging element having a collapsed delivery configuration and an expanded deployed configuration. The force that is applied on retraction of the elongate member is transmitted to the clot engaging element.

Abstract: A device for removing a clot from a blood vessel. The device can have a collapsed delivery configuration and an expanded deployed configuration. The device can have a shaft. An outer expandable body can be included that is radially expandable from a first radially expanded state to a second radially expanded state in the deployed configuration. An inner body can be included, wherein the outer expandable body and the inner body are fixedly coupled to a distal region of the shaft, the outer expandable body radially surrounding at least a portion of the inner body in the second radially expanded state. A capture net can be coupled to a distal portion of the inner body and including a proximal mouth.

Abstract: A clot retrieval system comprises a clot retrieval device, a catheter 51, and a tubular shield element 61. The clot retrieval device comprises an elongate member 53 having a proximal end and a distal end, and a clot engaging element 54 at the distal end of the elongate member 53 the clot engaging element 54 having a collapsed delivery configuration and an expanded deployed configuration. The catheter is adapted for placement at a location at which a distal end of the catheter is proximal of the clot engaging element and the tubular shield element 61 extends over the elongate member 53 and is adapted for location between the distal end of the catheter and the proximal end of the clot engaging element 54. The tubular shield element 61 is movable relative to the elongate member 54 when the clot engaging element is in the expanded configuration in that the force that is applied on retraction of the elongate member is spread over the outer surface of the tubular shield element.

Abstract: An embolic occlusion device for the treatment of aneurysms and arteriovenous malformations comprises expanded polytetrafluoroethylene (ePTFE). The ePTFE permits ingrowth of cells with connective tissue deposition to promote adherence of the aneurysm wall to the embolic device thereby preventing continued growth or re-growth of the aneurysm as well as blocking blood flow into an aneurysm. An occlusion device is also described which comprises an embolic element and a polymeric pre-formed component.

Abstract: A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Abstract: A system may comprise a clot engagement element having a collapsed delivery configuration and an expanded configuration for engaging with a clot and for dislodging the clot from a first vessel segment. An elongate member may be configured to apply a pull force to the clot engaging element to dislodge the clot from the first vessel segment. A clot removal catheter may include a lumen at its distal end sized to receive the clot and configured to maintain a stable position in a second blood vessel segment proximal of and larger in diameter than the first blood vessel segment. A distal end of the elongate member may be configured to protect a third blood vessel segment between the first and second blood vessel segments from tractive forces transmitted by the elongate member during clot dislodgement from the first vessel segment.

Abstract: A non-return valve, in particular for medical purposes, including a first hose connection housing, a second hose connection housing and a membrane disk which is made from flexible material. The membrane disk is arranged between the two hose connection housings and can be raised up from an annular valve seat in communication with an inlet space which is connected to an inlet passage. A medium-permeable formation which faces the membrane disk is arranged on the inlet side into the inlet space, supporting the membrane disk against overextension in the case of high return pressures.

Abstract: A system may comprise a clot engagement element having a collapsed delivery configuration and an expanded configuration for engaging with a clot and for dislodging the clot from a first vessel segment. An elongate member may be configured to apply a pull force to the clot engaging element to dislodge the clot from the first vessel segment. A clot removal catheter may include a lumen at its distal end sized to receive the clot and configured to maintain a stable position in a second blood vessel segment proximal of and larger in diameter than the first blood vessel segment. A distal end of the elongate member may be configured to protect a third blood vessel segment between the first and second blood vessel segments from tractive forces transmitted by the elongate member during clot dislodgement from the first vessel segment.

Abstract: A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Abstract: A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Abstract: A catheter has an expansile tip that can be delivered in a constricted form. The increased tip diameter facilitates the aspiration and removal of large clot volumes by increasing the area of the catheter tip that applies aspiration to the clot. The tip comprises a support frame which can be cut from a metal or polymer tube, covered with a thin polymer sleeve 909 containing highly elastic properties. This construction provides good pushability and high compressive resistance. The cut pattern can contain axial connections of the support frame and ring members, which will provide a large level of axial support, lateral flexibility and hoop strength to withstand aspiration. The tip of the device can contain a section proximal of the highly flexible area that can expand to except clot. This potential to increase body diameter facilitates the retrieval of large volume clots while the construction of the catheter provides good column stiffness to avoid axial collapse and still maintain good flexibility.

Abstract: A clot removal device for removing clot from a body vessel comprises an expandable structure and an elongate member. The expandable structure has a constrained delivery configuration, an expanded clot engaging deployed configuration, and an at least partially constrained clot pinching configuration. At least a portion of the expandable structure is configured to engage clot in the expanded deployed configuration and to pinch clot on movement from the deployed configuration to the clot capture configuration. The expandable structure may comprise a main body portion and a clot pinching structure and a diameter of the clot pinching structure is less than a diameter of the main body portion. The clot pinching structure may be substantially tubular and of spiral form.

Abstract: A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24,49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24,49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Abstract: A rapid exchange (RX) catheter may provide a proximal seal against a guide catheter inner lumen so that aspiration may be applied through a guide catheter. The catheter may include an exit port that defines a transfer port for aspiration and may enable minimal frictional engagement with the guide catheter proximal of the exit port. Aspiration can be applied to the lumen of the guide catheter and may be directed to and effective at the tip of the RX aspiration catheter. A tip of the RX catheter may facilitate aspiration and retrieval of the clot by expanding under load and can also partially or fully occlude the vessel.