Abstract: The invention relates to methods for altering biological parameters in a subject, such as reducing blood pressure in a subject, by displacing CLIP, using a CLIP inhibitor. The methods are useful for treating disorders such as preeclampsia and high blood pressure.

Abstract: A lockable strike (10) is disclosed which includes an exterior strike assembly (16) and an interior release assembly (17). The exterior strike assembly has a housing (25) and a rod receiver (30) with a slotted rod holder (32). The interior release assembly includes a pinned coupling rod (35), a lever (46), and a space adjuster (47). The pinned coupling rod is received within rod holder. The space adjuster includes an adjustment base (56) and a hub body (57). The adjustment base has a floor (63) with three stepped camming surfaces (65). The nub body also a floor (75) with three stepped camming surfaces (77) which are configured to ride upon the adjustment base camming surfaces. To adjust for varying thicknesses of a wall, the space adjuster is expanded in size by rotating the nub body relative to the adjustment base so that the camming surfaces more these components apart.

Abstract: There is disclosed an anti-sag hinge (10) which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a strap (31) extending from a cylinder portion (32). The strap includes elongated mounting holes (69), an adjustment screw boss (70) having a passageway (71), and a moveable adjustment bracket (77) having an adjustment screw mounting flange (78) with a threaded screw hole (79) therein in which is threadably mounted an adjustment screw (80). The adjustment screw has a head (81), a bearing flange (82), a neck (83), and a threaded shaft (84). A removable spacer (86) has a U-shaped gripping portion (87) which is snap fitted onto a portion of the threaded shaft between the bearing flange and the adjustment bracket screw flange. The adjustment bracket includes four mounting holes (88) extending therethrough and generally in alignment with strap elongated mounting holes.

Abstract: There is disclosed an anti-sag hinge (10) which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a strap (31) extending from a cylinder portion (32), The strap includes an interior recess (68) and a flexible, rubber bumper or cover (90) is configured to fit snugly into the top end of the strap recess. The recess is defined by the peripheral sidewalls (74) of the strap which extend to the most outboard portion of the hinge.

Abstract: There is disclosed an anti-sag hinge (10) which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a strap (31) extending from a cylinder portion (32). The strap includes elongated mounting holes (69), an adjustment screw boss (70) having a passageway (71), and a moveable adjustment bracket (77) having an adjustment screw mounting flange (78) with a threaded screw hole (79) therein in which is threadably mounted an adjustment screw (80). The adjustment screw has a head (81), a bearing flange (82), a neck (83), and a threaded shaft (84). A removable spacer (86) has a U-shaped gripping portion (87) which is snap fitted onto a portion of the threaded shaft between the bearing flange and the adjustment bracket screw flange. The adjustment bracket includes four mounting holes (88) extending therethrough and generally in alignment with strap elongated mounting holes.

Abstract: There is disclosed a LED light (10) including a lower housing (14), an upper housing (15), and a thermally insulative base gasket (16). The upper housing has a top wall (31) with a central mounting area (35) and a peripheral margin. The wall thickness of the central mounting area is thicker than that of the peripheral margin (38). The upper housing also includes a plurality of heat dissipating ribs (41) extending between the mounting area and the sidewalls. The ribs increase in height as they extend outwardly toward the sidewalls. The lighting portion includes a LED light array (37), a lens (48), and a lens gasket (49). With the LED array mounted to the central mounting area, heat generated by the LED array is conveyed to the central mounting area and then conveyed through the upper housing top wall and ribs to the sidewalls.

Abstract: There is disclosed anti-sag hinge (10) which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a strap (31) extending from a cylinder portion (32). The cylindrical portion includes a coupling end (34) with a vertically extending octagonal channel (35) therethrough. The octagonal channel includes a vertically extending alignment ridge or tongue (36) and a centrally positioned, horizontally oriented, annular ridge (37). The hinge also includes an elongated cam follower (40) having a lower cam follower portion (41) with an octagonal exterior surface (43) terminating at a circumferential ledge or shoulder (44) positioned to abut and bear against the centrally positioned annular ridge of the coupling end. The lower cam follower portion also has a longitudinally extending groove (53) configured to receive the coupling end alignment tongue.

Abstract: A vehicle lock strike (11) is disclosed for use with a latch (10) for a vehicle sliding door. The latch includes a two pivoting latch bar (16) having at least one pawl (19) with a stop surface (23). The lock strike includes a main plate (31) having a locking wall (33) with a L-shaped tang (35) which has an inwardly facing catch surface (36), a top surface (37), and an outwardly facing gap surface (38). The lock strike also includes a second plate (41) coupled to the locking wall having a top end surface (47), and an inwardly facing catch surface (48). A gap (50) is created between the tang and the second plate to receive a lower portion of the pawl. The top of the second plate is positioned higher than the top of the locking wall.

Abstract: A riser hinge (10) is disclosed which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The cylindrical portion (52) includes an upper strap bearing (54) and a lower strap bearing (55) which are each mounted partially within the cylindrical portion. The strap cylinder portion has a space (82) which includes an enlarged portion (83) flanked by narrowed portions (84) at stop ledges (85). The upper strap bearing and lower strap bearing each have a vertically oriented, elongated, locking tongue or flange (87) with a narrowed portion (88) extending to an enlarged portion or stop (89), which enables them to be removably mounted within the space.

Abstract: A riser hinge (10) is disclosed which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a camming assembly (27) having a multi-lobed cam 28 with a large lobe (38) and a small lobe (39). The lobes have a top bearing surfaces which extends to a flat dwell surface. The large lobe top dwell surface (41) is of a select size (arcuate length) which is longer than that of the small lobe top dwell surface (44). The camming assembly also includes a cam follower (56) having two cam following ridges (69). The asymmetrical configuration of the grooves creates a first, large ridge (70) and a second, small ridge (71). The bottom bearing surface (77) of the small ridge rides upon the top bearing surface of the small lobe. Similarly, the bottom bearing surface (73) of the large ridge rides upon the top bearing surface of the large lobe.

Abstract: A riser hinge (10) is disclosed which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The cylindrical portion (52) includes an upper strap bearing (54) and a lower strap bearing (55) which are each mounted partially within the cylindrical portion. The strap cylinder portion has a space (82) which includes an enlarged portion (83) flanked by narrowed portions (84) at stop ledges (85). The upper strap bearing and lower strap bearing each have a vertically oriented, elongated, locking tongue or flange (87) with a narrowed portion (88) extending to an enlarged portion or stop (89), which enables them to be removably mounted within the space.

Abstract: A riser hinge (10) is disclosed which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The cylindrical portion (52) includes an upper strap bearing (54) and a lower strap bearing (55) which are each mounted partially within the cylindrical portion. The strap cylinder portion has a space (82) which includes an enlarged portion (83) flanked by narrowed portions (84) at stop ledges (85). The upper strap bearing and lower strap bearing each have a vertically oriented, elongated, locking tongue or flange (87) with a narrowed portion (88) extending to an enlarged portion or stop (89), which enables them to be removably mounted within the space.

Abstract: A riser hinge (10) is disclosed which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The strap assembly includes a camming assembly (27) having a multi-lobed cam 28 with a large lobe (38) and a small lobe (39). The lobes have a top bearing surfaces which extends to a flat dwell surface. The large lobe top dwell surface (41) is of a select size (arcuate length) which is longer than that of the small lobe top dwell surface (44). The camming assembly also includes a cam follower (56) having two cam following ridges (69). The asymmetrical configuration of the grooves creates a first, large ridge (70) and a second, small ridge (71). The bottom bearing surface (77) of the small ridge rides upon the top bearing surface of the small lobe. Similarly, the bottom bearing surface (73) of the large ridge rides upon the top bearing surface of the large lobe.

Abstract: A light (10) for replacing a fluorescent bulb includes a base (33) with a two pin contact (35) which is configured to match that of a CFL bulb. The light also includes internal electronic ballast and surge protector circuitry (36). The circuitry is electrically coupled to a plurality of LED lights (37). The LED lights are mounted to a tubular mounting housing (38) and an end plate (40).

Abstract: A combination light (10) and light fixture (11) includes a light fixture having a main housing (12) and a cover (13). The cover has cylindrical side wall(s) (26) having an open end (27) and a semi-hemispherical dome closed end (28) defining the interior space (14). The side wall has a series of annular, circumferential prismatic ridges (31). The light is positioned within the interior space of the light fixture and optical cover. The light has a base (33) with a two pin contact (35) which is configured to match that of a GU-24 CFL bulb. The light also includes internal electronic ballast and surge protector circuitry (36). The circuitry is electrically coupled to a plurality of LED lights (37). The LED lights are mounted to a tubular mounting housing (38) and an end plate (40).

Abstract: There is disclosed a hinge (10) which includes a mounting flange assembly (12) pivotally coupled to a strap assembly (15). The mounting flange assembly includes a mounting flange (16) having four mounting holes (17) therethrough, a lower hinge barrel (18) extending from the mounting flange, and an upper hinge barrel (19) extending from the mounting flange. The strap assembly includes a strap (31) extending from a cylinder portion (32). The hinge also includes a main cover (57) covering the strap assembly, an upper flange cover (28) covering the upper hinge barrel, and a lower flange cover (29) covering the lower hinge barrel.