Patents by Inventor Brian A. Bernick

Brian A. Bernick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20180055855
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: August 2, 2017
    Publication date: March 1, 2018
    Applicant: TherapeuticsMD, Inc.
    Inventors: Julia AMADIO, Brian BERNICK, Peter H.R. PERSICANER
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20170340739
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: March 9, 2017
    Publication date: November 30, 2017
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20170216310
    Abstract: Disclosed herein is, among other things, a soft gel vaginal pharmaceutical composition and dosage form containing solubilized estradiol for the treatment of vulvovaginal atrophy (VVA) and female sexual dysfunction (FSD).
    Type: Application
    Filed: December 7, 2016
    Publication date: August 3, 2017
    Inventors: Sebastian Mirkin, Julia M. Amadio, Brian A. Bernick
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20170000803
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: September 6, 2016
    Publication date: January 5, 2017
    Applicant: TherapeuticsMD, Inc.
    Inventors: Julia Amadio, Brian Bernick, Peter H.R. Persicaner
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20160213685
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: April 4, 2016
    Publication date: July 28, 2016
    Inventors: BRIAN A. BERNICK, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • Natural combination hormone replacement formulations and therapies
    Patent number: 9301920
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 5, 2016
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 9289382
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: March 22, 2016
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio
  • Transdermal hormone replacement therapies
    Patent number: 9248136
    Abstract: Hormone replacement therapies are provided comprising solubilized progesterone alone and optionally with an estrogen, cyclic/sequential and continuous-combined dosing, and administered via transdermal HRT delivery systems.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: February 2, 2016
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Janice Louise Cacace, Neda Irani, Frederick D. Sancilio
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20150359737
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: June 18, 2013
    Publication date: December 17, 2015
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150352126
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: August 19, 2015
    Publication date: December 10, 2015
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150342963
    Abstract: Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil.
    Type: Application
    Filed: May 22, 2015
    Publication date: December 3, 2015
    Inventors: Brian A. Bernick, Peter H.R. Persicaner, Julia M. Amadio
  • Soluble estradiol capsule for vaginal insertion
    Patent number: 9180091
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: November 10, 2015
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Neda Irani, Janice Louise Cacace, Thorsteinn Thorsteinsson, Frederick D. Sancilio
  • SYSTEM AND METHOD OF ONGOING EVALUATION REPORTING AND ANALYSIS
    Publication number: 20150302435
    Abstract: A research and development system that gathers feedback from patients and healthcare providers with respect to the their experience with various aspects of a supplier's products in order to tabulate, consolidate, compare and analyze the data received rapidly and efficiently, and which can be used on successive iterations to determine future products and services.
    Type: Application
    Filed: May 4, 2015
    Publication date: October 22, 2015
    Inventors: Brian A. Bernick, Robert G. Finizio, John Milligan
  • Natural combination hormone replacement formulations and therapies
    Patent number: 9114145
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: August 25, 2015
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
  • Natural combination hormone replacement formulations and therapies
    Patent number: 9114146
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: August 25, 2015
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150224117
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: April 20, 2015
    Publication date: August 13, 2015
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150224118
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: April 20, 2015
    Publication date: August 13, 2015
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20150202211
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 23, 2015
    Applicant: TherapeuticsMD, Inc.
    Inventors: Julia Amadio, Brian Bernick
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20150196640
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 16, 2015
    Applicant: THERAPEUTICSMD, INC.
    Inventors: Janice Cacase, Peter Persicaner, Thorsteinn Thorsteinnson, Frederick Sancillio, Julia Amadio, Brian Bernick
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20150164789
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: February 17, 2015
    Publication date: June 18, 2015
    Inventors: Brian A. Bernick, Julia M. Amadio