Patents by Inventor Brian Connolly

Brian Connolly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11660104
    Abstract: An endovascular apparatus for crossing through an obstruction in a blood vessel comprises: an elongate endovascular element such as a wire; an ultrasonic transducer, mechanically coupled to the endovascular element for ultrasonically exciting a distal tip portion thereof to facilitate the crossing through the obstruction, and one or more damping features, mechanically coupled to the endovascular element to attenuate lateral displacement of the endovascular element at positions away from the distal tip portion.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: May 30, 2023
    Assignee: Versono Medical Limited
    Inventors: Finbar Dolan, Hugh O'Donoghue, Ivan Mooney, Pat Connolly, Jim Smedley, Brian Tarpey
  • Patent number: 11377787
    Abstract: The present invention is directed to dye mixtures comprising structures of formula and their production and their use for dyeing textiles and in particular for dyeing aramid fibres.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: July 5, 2022
    Assignee: DYSTAR COLOURS DISTRIBUTION GMBH
    Inventors: Adrian Murgatroyd, Manfred Hoppe, Clemens Grund, Brian Connolly, Thomas Stepanski
  • Patent number: 11370833
    Abstract: The invention provides stable aqueous pharmaceutical formulations comprising a therapeutic antibody, trehalose, a buffer, and optional surfactant, and having a pH in the range of about 5.5 to about 7.0. The invention also provides methods for making such formulations and methods of using such formulations.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: June 28, 2022
    Assignee: Genentech, Inc.
    Inventors: Lan Le, Brian Connolly
  • Publication number: 20220040312
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: January 22, 2021
    Publication date: February 10, 2022
    Applicant: Genentech, Inc.
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ
  • Patent number: 10933141
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: March 2, 2021
    Assignee: GENENTECH, INC.
    Inventors: Brian Connolly, Lydia Hamburg, Emily Holz
  • Patent number: 10869597
    Abstract: Methods, apparatus, and systems are provided for scanning and measuring an anatomical cavity. An apparatus may include an absorbing medium assembly that is fluidly connected to an earpiece and configured to provide an absorbing medium to the earpiece. The absorbing medium assembly may include a medium container with a gas trap, as well as a tube fluidly connected to the medium container. The gas trap may be located at a top portion of the medium container. The tube may be coupled to the top portion or a bottom portion of the medium container. The system may include a dip tube disposed inside the medium container when the tube of the absorbing medium assembly couples to a top portion of the medium container. A gas relief valve configured to enable gas to escape may also be present in the apparatus.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: December 22, 2020
    Assignee: LANTOS TECHNOLOGIES, INC.
    Inventors: Shawn M. Patterson, Steve Schmidt, Mac Andrew Dougan, Brian Connolly, Manas Menon, Lynn Ihlenfeldt
  • Publication number: 20200215195
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: November 21, 2019
    Publication date: July 9, 2020
    Applicant: Genentech, Inc.
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ
  • Patent number: 10525137
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: January 7, 2020
    Assignee: Genentech, Inc.
    Inventors: Brian Connolly, Lydia Hamburg, Emily Holz
  • Publication number: 20190338461
    Abstract: The present invention is directed to dye mixtures comprising structures of formula and their production and their use for dyeing textiles and in particular for dyeing aramid fibres.
    Type: Application
    Filed: December 7, 2017
    Publication date: November 7, 2019
    Inventors: ADRIAN MURGATROYD, Manfred HOPPE, Clemens GRUND, Brian CONNOLLY, Thomas STEPANSKI
  • Publication number: 20190161541
    Abstract: The invention provides stable aqueous pharmaceutical formulations comprising a therapeutic antibody, trehalose, a buffer, and optional surfactant, and having a pH in the range of about 5.5 to about 7.0. The invention also provides methods for making such formulations and methods of using such formulations.
    Type: Application
    Filed: July 3, 2018
    Publication date: May 30, 2019
    Inventors: Lan LE, Brian Connolly
  • Patent number: 10301475
    Abstract: The invention relates to mixtures of fiber-reactive Triphendioxazine dyes with other fiber-reactive azo dyes and their use for the dyeing of hydroxyl- and especially carboxamide-containing material in blue and navy shades.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: May 28, 2019
    Assignee: DryStar Colours Distribution GmbH
    Inventors: Adrian Murgatroyd, Manfred Hoppe, Clemens Grund, Brian Connolly, Thomas Stepanski
  • Publication number: 20180230311
    Abstract: The invention relates to mixtures of fibre-reactive Triphendioxazine dyes with other fibre-reactive azo dyes and their use for the dyeing of hydroxyl- and especially carboxamide-containing material in blue and navy shades.
    Type: Application
    Filed: October 26, 2016
    Publication date: August 16, 2018
    Inventors: Adrian MURGATROYD, Manfred HOPPE, Clemens GRUND, Brian CONNOLLY, Thomas STEPANSKI
  • Publication number: 20170189536
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: December 28, 2016
    Publication date: July 6, 2017
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ
  • Patent number: 9445619
    Abstract: Provided herein are exemplary compositions, products, and capsules utilizing POA, EPA, blends of POA and EPA, total algal oil compositions, and/or whole biomass compositions in methods of inhibiting inflammation including in cardiovascular disease, diabetes, obesity, stroke, metabolic syndromes, dementia, Alzheimer's disease, and/or cancer. The exemplary compositions, products, and capsules may be orally, topically, intravenously, and/or subcutaneously administered. The exemplary compositions herein may be used as feed, food, food supplements, beverages, beverage supplements, nutritional products, products for athletic performance, pharmaceutical products, and/or medical products for mammalian use, including humans.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: September 20, 2016
    Assignee: AURORA ALGAE, INC.
    Inventors: James Astwood, Michelle L. Collins, Brian Connolly
  • Publication number: 20160150949
    Abstract: Methods, apparatus, and systems are provided for scanning and measuring an anatomical cavity. An apparatus may include an absorbing medium assembly that is fluidly connected to an earpiece and configured to provide an absorbing medium to the earpiece. The absorbing medium assembly may include a medium container with a gas trap, as well as a tube fluidly connected to the medium container. The gas trap may be located at a top portion of the medium container. The tube may be coupled to the top portion or a bottom portion of the medium container. The system may include a dip tube disposed inside the medium container when the tube of the absorbing medium assembly couples to a top portion of the medium container. A gas relief valve configured to enable gas to escape may also be present in the apparatus.
    Type: Application
    Filed: November 24, 2015
    Publication date: June 2, 2016
    Inventors: Shawn M. Patterson, Steve Schmidt, Mac Andrew Dougan, Brian Connolly, Manas Menon, Lynn Ihlenfeldt
  • Publication number: 20160137727
    Abstract: The invention provides stable aqueous pharmaceutical formulations comprising a therapeutic antibody, trehalose, a buffer, and optional surfactant, and having a pH in the range of about 5.5 to about 7.0. The invention also provides methods for making such formulations and methods of using such formulations.
    Type: Application
    Filed: September 15, 2015
    Publication date: May 19, 2016
    Inventors: Lan LE, Brian CONNOLLY
  • Patent number: 8868613
    Abstract: Systems and methods, including computer software products, for updating data on a remote device involve defining multiple channels on a remote device, where each channel is associated with a predetermined type of content. Content updates for the channels are automatically delivered to the remote device, and an update frequency is identified for each channel. A most frequent update frequency among the multiple channels defined on the remote device is determined, and updates to the channels are requested according to the most frequent update frequency.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: October 21, 2014
    Assignee: Adobe Systems Incorporated
    Inventors: Antti Piira, Rupen Chanda, Brian Connolly
  • Publication number: 20140271706
    Abstract: Provided herein are exemplary compositions, products, and capsules utilizing POA, EPA, blends of POA and EPA, total algal oil compositions, and/or whole biomass compositions in methods of inhibiting inflammation including in cardiovascular disease, diabetes, obesity, stroke, metabolic syndromes, dementia, Alzheimer's disease, and/or cancer. The exemplary compositions, products, and capsules may be orally, topically, intravenously, and/or subcutaneously administered. The exemplary compositions herein may be used as feed, food, food supplements, beverages, beverage supplements, nutritional products, products for athletic performance, pharmaceutical products, and/or medical products for mammalian use, including humans.
    Type: Application
    Filed: September 12, 2013
    Publication date: September 18, 2014
    Applicant: Aurora Algae, Inc.
    Inventors: James Astwood, Michelle L. Collins, Brian Connolly
  • Patent number: 8214619
    Abstract: Systems and methods, including computer software stored on a machine-readable medium for performing operations, can be implemented for allocating memory. Multiple channels are defined on a mobile device. Each channel can be adapted to receive a predetermined type of content for access on the mobile device. An amount of memory allocated to each channel for storing data is defined. Data identifying a new amount of memory allocated to one of the channels is received, and the amount of memory allocated to the channel is adjusted based on the data identifying the new amount of memory.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: July 3, 2012
    Assignee: Adobe Systems Incorporated
    Inventors: Brian Connolly, Rupen Chanda
  • Publication number: 20120046203
    Abstract: The invention provides analyzers that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient and specific selection and sensitive imaging detection of individual microscopic targets at low magnification. Automated embodiments allow efficient walk-away, on-demand, random-access high-throughput testing. The analyzers perform tests without requiring wash steps thus streamlining engineering and lowering costs. Thus, the invention provides analyzers that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests for analytes.
    Type: Application
    Filed: September 24, 2009
    Publication date: February 23, 2012
    Applicant: Straus Holdings Inc.
    Inventors: Bruce Walsh, Boris Blanter, Matthew Barra, Brian Connolly, Greg Yantz, Paul Gervasio, Don Straus