Abstract: Embodiments of device for monitoring pressure in the left atrium are provided. The device is delivered to the left atrium via the coronary sinus. A first portion of the device is deployed in the left atrium, the first portion of the device comprising a pressure sensor. A second portion of the device is deployed in the coronary sinus. Monitoring left atrial pressure via coronary sinus access can provide a safer, less invasive way to monitor a patient for heart failure.

Abstract: The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes interatrial shunting systems that include a shunting element having a lumen extending therethrough that is configured to fluidly couple the left atrium and the right atrium when the shunting element is implanted in a patient. The system can also include an energy receiving component for receiving energy from an energy source positioned external to the body, an energy storage component for storing the received energy, and/or a flow control mechanism for adjusting a geometry of the lumen.

Abstract: Systems, devices, and methods involve ablation of tissue to treat rhinitis and/or other nasal conditions. Implementations allow treatment of tissue in the confined space of the nasal cavity. Additionally, implementations allow targeted treatment tissue to be ablated, while protecting other non-treatment tissue from unintentional collateral effects that might be produced by the ablation. According to an example implementation, an approach for treating a nasal condition includes advancing a probe into a nasal cavity, the probe including a shaft and a cryotherapy element coupled to the shaft. The approach also includes cryogenically cooling a target treatment site with the cryotherapy element to treat at least one nasal nerve. Additionally, the approach includes transmitting a focused ultrasound beam to a target heating site to increase a temperature tissue at the target heating site.

Abstract: The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and/or a geometry of a lumen orifice to control the flow of blood through the lumen.

Abstract: The present disclosure provides apparatuses and methods for treating conditions such as chronic daily headache, cluster headache, tension headache, migraine, or acute headache of a patient. In example methods, a cryotherapy element is introduced into the nasal cavity or pterygopalatine fossa to cool or cryoablate at least one of a nasal nerve tissue or nasal blood vessel. The cryotherapy element may be introduced into the nasal cavity in a collapsed position, and prior to cooling a target treatment site may be expanded to an expanded configuration.

Abstract: In an example, a method for delivery of a therapeutic agent to at least one of a palatine canal or a pterygopalatine fossa of a patient is described. The method includes inserting a delivery device into a nasal cavity of a patient. The delivery device includes an elongated shaft with a proximal end and a distal end, a handpiece coupled to the proximal end of the elongated shaft, and a boring element disposed on the distal end of the elongated shaft. The method also includes advancing the distal end of the elongated shaft to a position proximate to a palatine bone within the nasal cavity, actuating the boring element to form a passage in the palatine bone between the nasal cavity and a palatine canal of the patient, and delivering a therapeutic agent into the palatine canal.

Abstract: The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and/or a geometry of a lumen orifice to control the flow of blood through the lumen.

Abstract: The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and/or a geometry of a lumen orifice to control the flow of blood through the lumen.

Abstract: The present disclosure provides an apparatus for delivering an anesthetic agent to a target tissue in a nasal cavity of a patient. The apparatus includes an elongated shaft with a proximal end and a distal end. The apparatus also includes an absorbent plug coupled to the distal end of the elongated shaft. The absorbent plug is configured to occupy a first volume in a compressed state and a second volume in an uncompressed state. The absorbent plug is configured to store an anesthetic agent and deliver the anesthetic agent to the target tissue in the nasal cavity by contacting the target tissue. The apparatus also includes a sheath at least partially covering the absorbent plug. The sheath retains the absorbent plug in the compressed state when positioned at least partially over the absorbent plug, and removal of the sheath allows for the absorbent plug to expand to the uncompressed state.

Abstract: Apparatus and methods for treating and monitoring conditions such as rhinitis are disclosed herein. The technology utilizes ultrasound scans to identify target treatment sites, and monitor the treatment of a patient undergoing a treatment. The treatment may be an ablation treatment of a nasal nerve, for example the PNN for the treatment of nasal conditions, such as rhinitis. The ultrasound scans are performed within the nasal cavity with an ultrasound probe or a combined ultrasound and ablation probe and may use Doppler, A-mode, B-mode, M-mode or other ultrasound and non-ultrasound modalities to detect and monitor the target treatment sites.

Abstract: The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes and sensors may be provided, such that signals provided by the sensors may affect the signals provided to the stimulation electrodes, thus providing a feedback. Stimulation electrodes may be provided on a stimulation pad and sensors may be provided on a sensing pad, which may be designed to conform to an anatomical feature. A system for neuromuscular electrical stimulation may also include temperature sensitive elements that may help prevent burns, especially for comatose, sedated, or patients in critical condition. The system may also include a cooling assembly for a stimulation pad.

Abstract: The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes may be provided on a stimulation pad, configured to provide electrical stimulation to a target tissue. A system for neuromuscular electrical stimulation may also include pressure generating mechanisms that may provide a compressive force to a region with the target tissue, thereby removing some excess third space fluid from the region.

Abstract: The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes may be provided on a stimulation pad, configured to provide electrical stimulation to a target tissue. A system for neuromuscular electrical stimulation may also include pressure generating mechanisms that may provide a compressive force to a region with the target tissue, thereby removing some excess third space fluid from the region.

Abstract: The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes and sensors may be provided, such that signals provided by the sensors may affect the signals provided to the stimulation electrodes, thus providing a feedback. Stimulation electrodes may be provided on a stimulation pad and sensors may be provided on a sensing pad, which may be designed to conform to an anatomical feature. A system for neuromuscular electrical stimulation may also include temperature sensitive elements that may help prevent burns, especially for comatose, sedated, or patients in critical condition. The system may also include a cooling assembly for a stimulation pad.

Abstract: A system for fetal position-independent, non-invasive fetal monitoring includes a plurality of disposable adhesive patches for placement on an expectant mother's upper and lower abdomen. Each of the patches includes one or more miniature electronic devices embedded within the adhesive patches to detect: (i) heart sounds of a fetus within the mother, (ii) heart sounds of the mother, and (iii) signals indicative of uterine contractions of the mother. A processing hub having a receiver to receive signals from the plurality of patches, wherein the processing hub receives and processes primary signal from the primary patch and the secondary signals from the secondary patches to triangulate the location of the fetus, cancel noise in the primary signal and increase the amplitude of the primary signal for more reliable reporting.

Abstract: A compliance management system that includes a task module configured to process a task comprising task attributes, to associate the tasks with a workflow, and to assign the task to one or more individuals based on a task assignment attribute, the task assignment attribute representing one or more individuals responsible for the task. The system also includes a case module configured to process a case comprising case attributes and to track the resolution and method of resolution of the case and a document module configured to store or retrieve documents, and to associate the documents with one or more tasks or cases.

Abstract: Ultrasound methods of distinguishing ablated tissue from unablated tissue include scanning ablated tissue using Acoustic Radiation Force Impulse (ARFI) imaging. ARFI image data is generated based on the scanning. The image data includes a portion of increased stiffness representing the ablated tissue that is distinguishable from unablated tissue.