Patents by Inventor Brian Fox

Brian Fox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220377424
    Abstract: According to examples, a system for providing dynamic digital content may include a processor and a memory storing instructions. The processor, when executing the instructions, may cause the system to receive a plurality of data feeds. The processor may further analyze the data feeds to identify values for parameterized variables. A plurality of deep learning (DL) models can be trained to obtain product attribute data from the data feeds. The processor may then identify rules or triggers based on the values of the parameterized variables. The rules and/or triggers cause the processor to dynamically generate or select digital content and transmit the digital content to user communication devices of selected audience.
    Type: Application
    Filed: May 6, 2022
    Publication date: November 24, 2022
    Applicant: Meta Platforms, Inc.
    Inventors: Zi Yu Daniel DENG, Brian FOX, Keenan Christopher PRIDMORE, Aditi RAJAGOPAL, Dana Michelle JEFFERSON, Daniel BOTTAS, Cynthia AGUSTINA, Oleg PASHKOVSKY
  • Publication number: 20220329467
    Abstract: A pair of ground planes arranged in parallel, a dielectric medium disposed in between the pair of ground planes, and a set of at least four signal conductors disposed in the dielectric medium, the set of at least four signal conductors having (i) a first pair of signal conductors arranged proximate to a first ground plane of the pair of ground planes and (ii) a second pair of signal conductors arranged proximate to a second ground plane of the pair of ground planes, each signal conductor of the set of at least four signal conductors configured to carry a respective signal corresponding to a symbol of a codeword of a vector signaling code.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 13, 2022
    Inventors: John Fox, Brian Holden, Ali Hormati, Peter Hunt, John D. Keay, Amin Shokrollahi, Richard Simpson, Anant Singh, Andrew Kevin John Stewart, Giuseppe Surace, Roger Ulrich
  • Patent number: 11455400
    Abstract: A computer system for security of components includes at least one processor. For a new version of a component, the processor determines, based on a dataset of release events over time, a historical behavioral analysis of (i) a project that is released with prior versions of the component, and/or (ii) historical committer behavior of a committer that committed the new version of the component, and/or (iii) historical behavior of a publisher of the project. The dataset of release events includes event data collected over time regarding open source project, committers, and repository. The processor determines whether the new version of the component presents an unusual risk profile, based on the historical behavioral analysis. The processor facilitates delayed consumption of the new version of the component in response to determining that the new version of the component presents the unusual risk profile.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: September 27, 2022
    Assignee: Sonatype, Inc.
    Inventors: Brian Fox, Bruce Mayhew, Jason Dillon, Gazi Mahmud
  • Publication number: 20220298222
    Abstract: Provided are methods, uses, and articles of manufacture of combination therapies involving immunotherapies and cell therapies, such as adoptive cell therapy, e.g. a T cell therapy, and the use of an inhibitor of an enhancer of zeste homolog 2 (EZH2), for treating subjects having or suspected of having a cancer, and related methods, uses, and articles of manufacture. The T cell therapy includes cells that express recombinant receptors such as chimeric antigen receptors (CARs).
    Type: Application
    Filed: August 21, 2020
    Publication date: September 22, 2022
    Applicant: Juno Therapeutics, Inc.
    Inventors: Henry CHANG, Ellen FILVAROFF, Brian FOX, Adithi MOHAN, Katie NEWHALL, Nels Eric OLSON
  • Patent number: 11447754
    Abstract: Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, ?-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The ?-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: September 20, 2022
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Timothy James Donohue, Daniel Leo Gall, Wayne S. Kontur, Hoon Kim, John Ralph, Daniel R. Noguera, Brian Fox, Craig Bingman
  • Publication number: 20220273654
    Abstract: Methods are provided for the treatment of cancer or neoplastic diseases and the like, by administering 4-[2-(4-amino-piperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyrimidin-4-yl]-2-fluoro- benzonitrile (compound of Formula (I)) or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising compounds useful for the inhibition of lysine specific demethylase-1 (LSD-1) to patients in need thereof. Methods are further drawn to administering compositions described herein to patients having neoplastic cells that express RCOR2.
    Type: Application
    Filed: June 12, 2020
    Publication date: September 1, 2022
    Applicant: Celgene Corporation
    Inventors: Ellen Filvaroff, Brian Fox, Ida Aronchik, Tracy Chow
  • Patent number: 11374801
    Abstract: A pair of ground planes arranged in parallel, a dielectric medium disposed in between the pair of ground planes, and a set of at least four signal conductors disposed in the dielectric medium, the set of at least four signal conductors having (i) a first pair of signal conductors arranged proximate to a first ground plane of the pair of ground planes and (ii) a second pair of signal conductors arranged proximate to a second ground plane of the pair of ground planes, each signal conductor of the set of at least four signal conductors configured to carry a respective signal corresponding to a symbol of a codeword of a vector signaling code.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: June 28, 2022
    Assignee: KANDOU LABS, S.A.
    Inventors: John Fox, Brian Holden, Ali Hormati, Peter Hunt, John D. Keay, Amin Shokrollahi, Richard Simpson, Anant Singh, Andrew Kevin John Stewart, Giuseppe Surace, Roger Ulrich
  • Publication number: 20220150553
    Abstract: According to examples, a system for generating and delivering enhanced content utilizing remote rendering and data streaming is described. The system may include a processor and a memory storing instructions. The processor, when executing the instructions, may cause the system to transmit a selected engagement content item for transmission to a user device and receive an indication of interest relating to the selected engagement content item. The processor, when executing the instructions, may then select, based on the received indication of interest, an enhanced content item, process the enhanced to content item to generate a stream of content data associated with the enhanced content item and transmit the stream of content data associated with the enhanced content item to the user device.
    Type: Application
    Filed: November 9, 2021
    Publication date: May 12, 2022
    Applicant: Facebook, Inc.
    Inventors: Rakesh RAVURU, Brian FOX, Keenan Christopher PRIDMORE, Miguel Angel PEREZ, Xin ZHOU, Adetunji Toritseju OLOJEDE, Kyle Scot SHANK, Robert Thomas MOAKLER, Nikhil Girish NAWATHE, Lara Jessamine ANDREWS, Tatiana Borrell PECK, Rotem DRUKER, Siqi HUANG, Siyi WANG, Hoang Viet NGUYEN
  • Publication number: 20220063045
    Abstract: An abrasive blast cabinet uses a space frame to support panels defining an enclosed volume. One of the panels defines a view port and access ports. Illumination devices positioned on the one panel adjacent to and/or surrounding the view port illuminate the enclosed volume without significant shadowing, glare or reflections. The illumination devices are captured between a frame and the one panel and are protected from the blast environment by channel members which are covered by a transparent plate overlying the view port.
    Type: Application
    Filed: June 30, 2021
    Publication date: March 3, 2022
    Inventors: Brandon Acker, Brian Fox
  • Publication number: 20220041620
    Abstract: The present disclosure relates generally to compounds and compositions, intermediates, processes for their preparation, and their use as kinase inhibitors.
    Type: Application
    Filed: October 26, 2021
    Publication date: February 10, 2022
    Applicant: Denali Therapeutics Inc.
    Inventors: Javier de Vicente Fidalgo, Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cinzia Maria Francini, Christopher R.H. Hale, Cheng Hu, Colin Philip Leslie, Maksim Osipov, Elena Serra, Zachary K. Sweeney, Arun Thottumkara
  • Publication number: 20220024938
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Application
    Filed: October 5, 2021
    Publication date: January 27, 2022
    Applicant: Denali Therapeutics Inc.
    Inventors: Giorgio Bonanomi, Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cinzia Maria Francini, Cheng Hu, Colin Philip Leslie, Maksim Osipov, Anantha Sudhakar, Zachary K. Sweeney, Javier De Vicente Fidalgo
  • Publication number: 20220002744
    Abstract: The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAHD acyltransferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.
    Type: Application
    Filed: November 8, 2019
    Publication date: January 6, 2022
    Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Steven D. Karlen, Rebecca Anne Smith, John Ralph, Emily Beebe, Craig Bingman, Brian Fox, Shawn Mansfield, Heather Mackay, Hoon Kim, Yaseen Mottiar, Faride Unda
  • Patent number: 11203600
    Abstract: The present disclosure relates generally to compounds and compositions, intermediates, processes for their preparation, and their use as kinase inhibitors.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: December 21, 2021
    Assignee: DENALI THERAPEUTICS INC.
    Inventors: Javier De Vicente Fidalgo, Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cinzia Maria Francini, Christopher R. H. Hale, Cheng Hu, Colin Philip Leslie, Maksim Osipov, Elena Serra, Zachary K. Sweeney, Arun Thottumkara
  • Patent number: 11174262
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 16, 2021
    Assignee: Denali Therapeutics Inc.
    Inventors: Giorgio Bonanomi, Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cinzia Maria Francini, Cheng Hu, Colin Philip Leslie, Maksim Osipov, Anantha Sudhakar, Zachary K. Sweeney, Javier De Vicente Fidalgo
  • Publication number: 20210332058
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Application
    Filed: June 17, 2021
    Publication date: October 28, 2021
    Applicant: Denali Therapeutics Inc.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cheng Hu, Maksim Osipov, Zachary K. Sweeney, Javier de Vicente Fidalgo, Arun Thottumkara
  • Patent number: 11072618
    Abstract: The present disclosure relates generally to methods and compositions for preventing or arresting cell death and/or inflammation.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: July 27, 2021
    Assignee: DENALI THERAPEUTICS INC.
    Inventors: Anthony A. Estrada, Jianwen A. Feng, Brian Fox, Cheng Hu, Maksim Osipov, Zachary K. Sweeney, Javier de Vicente Fidalgo, Arun Thottumkara
  • Publication number: 20210207104
    Abstract: The invention relates to feruloyl-CoA:monolignol transferase enzymes and nucleic acids encoding the feruloyl-CoA:monolignol transferase enzymes. The enzymes and/or the nucleic acids enable incorporation of monolignol ferulates into the lignin of plants. The monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate.
    Type: Application
    Filed: November 30, 2020
    Publication date: July 8, 2021
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
  • Publication number: 20210095263
    Abstract: The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of p-coumaroyl-CoA:monolignol transferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.
    Type: Application
    Filed: November 30, 2020
    Publication date: April 1, 2021
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
  • Publication number: 20210095265
    Abstract: Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, ?-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The ?-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.
    Type: Application
    Filed: September 30, 2020
    Publication date: April 1, 2021
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Timothy James Donohue, Daniel Leo Gall, Wayne S. Kontur, Hoon Kim, John Ralph, Daniel R. Noguera, Brian Fox, Craig Bingman
  • Publication number: 20210056209
    Abstract: A computer system for security of components includes at least one processor. For a new version of a component, the processor determines, based on a dataset of release events over time, a historical behavioral analysis of (i) a project that is released with prior versions of the component, and/or (ii) historical committer behavior of a committer that committed the new version of the component, and/or (iii) historical behavior of a publisher of the project. The dataset of release events includes event data collected over time regarding open source project, committers, and repository. The processor determines whether the new version of the component presents an unusual risk profile, based on the historical behavioral analysis. The processor facilitates delayed consumption of the new version of the component in response to determining that the new version of the component presents the unusual risk profile.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 25, 2021
    Inventors: Brian FOX, Bruce MAYHEW, Jason DILLON, Gazi MAHMUD