Abstract: The present invention relates to novel cyclic peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders. The inhibitor of an interleukin-23 receptor is cyclized by a disulfide bond between penicillamine, cysteine, homocysteine, or alpha methylcysteine residues at positions X4 and X9.

Abstract: Aspects of this technical solution can determine, based on power applied to a vehicle from a source of power and power consumed by the vehicle, an emission metric corresponding to the vehicle, and send a request to a second system, the request to link with an asset based on the emission metric.

Abstract: The present invention relates to novel bicyclic peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.

Abstract: Described is a recombinant expression vector that enables a cell transformed to contain and express the vector to use levulinic acid as a carbon source, thereby converting levulnic acid into 2-butanne. Also described are genetically modified cells transformed to contain and express the vector and methods of using the cells to produce 2-butanone from a medium containing levulinic acid.

Abstract: A novel soybean variety, designated 5PEUR38 is provided. Also provided are the seeds of soybean variety 5PEUR38, cells from soybean variety 5PEUR38, plants of soybean 5PEUR38, and plant parts of soybean variety 5PEUR38. Methods provided include producing a soybean plant by crossing soybean variety 5PEUR38 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PEUR38, methods for producing other soybean varieties or plant parts derived from soybean variety 5PEUR38, and methods of characterizing soybean variety 5PEUR38. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PEUR38 are further provided.

Abstract: The present invention relates to novel lipidated peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof, corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders.

Abstract: A novel soybean variety, designated 5PVZL16 is provided. Also provided are the seeds of soybean variety 5PVZL16, cells from soybean variety 5PVZL16, plants of soybean 5PVZL16, and plant parts of soybean variety 5PVZL16. Methods provided include producing a soybean plant by crossing soybean variety 5PVZL16 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PVZL16, methods for producing other soybean varieties or plant parts derived from soybean variety 5PVZL16, and methods of characterizing soybean variety 5PVZL16. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PVZL16 are further provided.

Abstract: A novel soybean variety, designated 5PMHT38 is provided. Also provided are the seeds of soybean variety 5PMHT38, cells from soybean variety 5PMHT38, plants of soybean 5PMHT38, and plant parts of soybean variety 5PMHT38. Methods provided include producing a soybean plant by crossing soybean variety 5PMHT38 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PMHT38, methods for producing other soybean varieties or plant parts derived from soybean variety 5PMHT38, and methods of characterizing soybean variety 5PMHT38. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PMHT38 are further provided.

Abstract: A liner hanger system enables installation of a liner hanger by means of a full bore casing to surface and provides pressure integrity between the casing's inner and outer sides. The liner hanger system comprises a liner hanger, along with an associated liner, coupled to a tieback casing string. The liner hanger and liner are deployed downhole connected to a tieback casing string. Once the liner has been lowered to the position of interest, first the liner hanger is anchored and cemented in position, and then, a packer is set to seal the lower annulus of the liner. The liner hanger system enables operations that used to require a plurality of trips, to be performed in a single trip. It does so without introducing any unwanted limitation to the inner diameter at any point between the wellhead and the end of the liner, and while also allowing for potential decoupling and removal of the tieback casing string from the liner hanger if desired.

Abstract: This document describes methods, systems and computer program products related to cloud-based rendering. The subject matter of this document is embodied in a method that includes receiving, at a server, information associated with a job of rendering one or more frames at the server, and using, at the server, an application to perform at least a portion of the rendering. The use of the application to perform the rendering bears a charge according to a usage license associated with the application. The method also includes measuring, at the server, an amount of use of the application in performing the rendering for use in determining the charge.

Abstract: A novel soybean variety, designated 5PVZL16 is provided. Also provided are the seeds of soybean variety 5PVZL16, cells from soybean variety 5PVZL16, plants of soybean 5PVZL16, and plant parts of soybean variety 5PVZL16. Methods provided include producing a soybean plant by crossing soybean variety 5PVZL16 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PVZL16, methods for producing other soybean varieties or plant parts derived from soybean variety 5PVZL16, and methods of characterizing soybean variety 5PVZL16. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PVZL16 are further provided.

Abstract: A novel soybean variety, designated 5PEUR38 is provided. Also provided are the seeds of soybean variety 5PEUR38, cells from soybean variety 5PEUR38, plants of soybean 5PEUR38, and plant parts of soybean variety 5PEUR38. Methods provided include producing a soybean plant by crossing soybean variety 5PEUR38 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PEUR38, methods for producing other soybean varieties or plant parts derived from soybean variety 5PEUR38, and methods of characterizing soybean variety 5PEUR38. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PEUR38 are further provided.

Abstract: The present disclosure pertains to cryogenic devices and related methods. A ferrule coupling according to at least some aspects of the present disclosure may include a male fitting including a bore; a female fitting including a bore, the female fitting sized to receive the male fitting; a conduit sized to fit within the bores of the male fitting and the female fitting, wherein a circumferential gap exists between an exterior of the conduit and an interior surface of the female fitting demarcating the bore; a first ferrule including dual conical surfaces and a cylindrical bore, the cylindrical bore sized to receive the conduit; a second ferrule including dual conical surfaces and a cylindrical bore, the cylindrical bore sized to receive the conduit; and/or a washer including dual conical surfaces and a cylindrical bore, the cylindrical bore sized to receive the conduit.

Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable xylanase that is resistance to inhibition by metal ions in the liquefying starch-containing material is present and/or added during liquefaction.

Abstract: This document describes methods, systems and computer program products related to cloud-based rendering. The subject matter of this document is embodied in a method that includes receiving, at a server, information associated with a job of rendering one or more frames at the server, and using, at the server, an application to perform at least a portion of the rendering. The use of the application to perform the rendering bears a charge according to a usage license associated with the application. The method also includes measuring, at the server, an amount of use of the application in performing the rendering for use in determining the charge.

Abstract: A novel soybean variety, designated 5PTSD37 is provided. Also provided are the seeds of soybean variety 5PTSD37, cells from soybean variety 5PTSD37, plants of soybean 5PTSD37, and plant parts of soybean variety 5PTSD37. Methods provided include producing a soybean plant by crossing soybean variety 5PTSD37 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PTSD37, methods for producing other soybean varieties or plant parts derived from soybean variety 5PTSD37, and methods of characterizing soybean variety 5PTSD37. Soybean seed, cells, plants, germ plasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PTSD37 are further provided.

Abstract: A liner hanger system enables installation of a liner hanger by means of a full bore casing to surface and provides pressure integrity between the casing's inner and outer sides. The liner hanger system comprises a liner hanger, along with an associated liner, coupled to a tieback casing string. The liner hanger and liner are deployed downhole connected to a tieback casing string. Once the liner has been lowered to the position of interest, first the liner hanger is anchored and cemented in position, and then, a packer is set to seal the lower annulus of the liner. The liner hanger system enables operations that used to require a plurality of trips, to be performed in a single trip. It does so without introducing any unwanted limitation to the inner diameter at any point between the wellhead and the end of the liner, and while also allowing for potential decoupling and removal of the tieback casing string from the liner hanger if desired.

Abstract: A method, computer system, and a computer program product for object notifications is provided. The present invention may include receiving a requestor's operation. The present invention may then include determining that a notification describing the requestor's operation should be sent. The present invention may then include determining whether the requestor's operation is successful or unsuccessful, and the present invention may lastly include deleting an in-memory object.

Abstract: Described is a recombinant expression vector that enables a cell transformed to contain and express the vector to use levulinic acid as a carbon source, thereby converting levulnic acid into 2-butanne. Also described are genetically modified cells transformed to contain and express the vector and methods of using the cells to produce 2-butanone from a medium containing levulinic acid.

Abstract: Cells and methods for producing polyhydroxyalkanoates. The cells comprise one or more recombinant genes selected from an R-specific enoyl-CoA hydratase gene, a PHA polymerase gene, a thioesterase gene, and an acyl-CoA-synthetase gene. The cells further have one or more genes functionally deleted. The functionally deleted genes include such genes as an enoyl-CoA hydratase gene, a 3-hydroxyacyl-CoA dehydrogenase, and a 3-ketoacyl-CoA thiolase gene. The recombinant cells are capable of using producing polyhydroxyalkanoates with a high proportion of monomers having the same carbon length from non-lipid substrates, such as carbohydrates.