Patents by Inventor Brian Hess
Brian Hess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10604715Abstract: The present application relates to compositions comprising at least one polyalkyl(meth)acrylate polymer, a graft copolymer comprising a copolymer based on ethylene as graft base and one or more polyalkyl(meth)acrylate polymer(s) grafted thereon, and at least one non-grafted ethylene-based copolymer, as well as to the use of such compositions to improve the performance, especially the cold flow properties and injector nozzle coking tendency of middle distillates, especially diesel fuels, biodiesel and blends thereof.Type: GrantFiled: February 3, 2014Date of Patent: March 31, 2020Assignee: EVONIK OPERATIONS GmbHInventors: Frank-Olaf Maehling, Ronny Sondjaja, Brian Hess, Julien Couet, Dennis Thong
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Patent number: 10131786Abstract: A method of synthesizing copolymers is provided. The method can include coupling a degradable polymer to a poly(amino acid) and then deprotecting the copolymer if the poly(amino acid) contains protected side chains. Copolymer compositions are provided. These compositions include PLGA-PLL copolymers, PLGA-PLL-cbz copolymers, and copolymers of a polyester with a carboxylic acid end group coupled to a poly(amino acid) with an amine group. The compositions may include therapeutic blends and formulations of copolymers.Type: GrantFiled: July 13, 2012Date of Patent: November 20, 2018Assignees: INVIVO THERAPEUTICS CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: John Harvey, Daniel Siegwart, Heng Lian Huang, Brian Hess, Alex Aimetti
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Patent number: 9957342Abstract: The present invention relates to a process for preparing grafted polyalkyl(meth)acrylates (PAMAs) containing dispersant repeating units in the polymer backbone as well as in the grafted layer, which polymers are characterized by a low sulfur content, the products available by this process and their use as an additive to fuels, especially to middle distillates and blends thereof. The present invention further relates to a composition comprising the grafted polyalkyl(meth)acrylates prepared by the process according to the present invention and the use of said composition as an additive component to fuels, especially to middle distillates and blends thereof, and for improving the cold flow properties of fuel oil and fuel oil compositions, especially to middle distillate fuels and blends thereof.Type: GrantFiled: October 8, 2013Date of Patent: May 1, 2018Assignee: Evonik Oil Additives GmbHInventors: Justin August Langston, Barbara Voltz, Frank-Olaf Maehling, Michael G Duckworth, Brian Hess, Rhishikesh Gokhale
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Publication number: 20160279281Abstract: Certain small molecule amino acid phosphate compounds such as phosphoserine and certain multivalent metal compounds such as calcium phosphate containing cements have been found to have improved properties and form an interpenetrating network in the presence of a polymer that contains either an electronegative carbonyl oxygen atom of the ester group or an electronegative nitrogen atom of the amine group as the bonding sites of the polymer surfaces to the available multivalent metal ions.Type: ApplicationFiled: December 28, 2015Publication date: September 29, 2016Inventors: Venkat R. Garigapati, Brian Hess, Cassandra L. Kimsey, Matthew E. Murphy
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Publication number: 20150344801Abstract: The present application relates to compositions comprising at least one polyalkyl(meth)acrylate polymer, a graft copolymer comprising a copolymer based on ethylene as graft base and one or more polyalkyl(meth)acrylate polymer(s) grafted thereon, and at least one non-grafted ethylene-based copolymer, as well as to the use of such compositions to improve the performance, especially the cold flow properties and injector nozzle coking tendency of middle distillates, especially diesel fuels, biodiesel and blends thereof.Type: ApplicationFiled: February 3, 2014Publication date: December 3, 2015Applicant: EVONIK OIL ADDITIVES GMBHInventors: Frank-Olaf MÄHLING, Ronny SONDJAJA, Brian HESS, Julien COUET, Dennis THONG
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Publication number: 20150274875Abstract: The present invention relates to a process for preparing grafted polyalkyl(meth)acrylates (PAMAs) containing dispersant repeating units in the polymer backbone as well as in the grafted layer, which polymers are characterized by a low sulfur content, the products available by this process and their use as an additive to fuels, especially to middle distillates and blends thereof. The present invention further relates to a composition comprising the grafted polyalkyl(meth)acrylates prepared by the process according to the present invention and the use of said composition as an additive component to fuels, especially to middle distillates and blends thereof, and for improving the cold flow properties of fuel oil and fuel oil compositions, especially to middle distillate fuels and blends thereof.Type: ApplicationFiled: October 8, 2013Publication date: October 1, 2015Applicant: EVONIK INDUSTRIES AGInventors: Justin August Langston, Barbara Voltz, Frank-Olaf Maehling, Michael G Duckworth, Brian Hess, Rhishikesh Gokhale
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Publication number: 20150166786Abstract: A method of synthesizing copolymers is provided. The method can include coupling a degradable polymer to a poly(amino acid) and then deprotecting the copolymer if the poly(amino acid) contains protected side chains. Copolymer compositions are provided. These compositions include PLGA-PLL copolymers, PLGA-PLL-cbz copolymers, and copolymers of a polyester with a carboxylic acid end group coupled to a poly(amino acid) with an amine group. The compositions may include therapeutic blends and formulations of copolymers.Type: ApplicationFiled: July 13, 2012Publication date: June 18, 2015Applicant: InVivo Therapeutics Corp.Inventors: John Harvey, Daniel Siegwart, Heng Huang, Brian Hess, Alex Aimetti
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Patent number: 8945134Abstract: A stand for use with a syringe is disclosed. The stand includes a base and a clip affixed to the base. The clip engages a portion of the syringe so as to removably secure the syringe to the stand in a position such that the distal end of the syringe is spaced vertically away from the base. Preferably, the syringe includes a handle extending outwardly from a barrel of the syringe, and the feature which the clip engages includes the handle of the syringe.Type: GrantFiled: March 11, 2013Date of Patent: February 3, 2015Assignee: Stryker Leibinger GmbH & Co. KGInventors: Brian Hess, Matthew E. Murphy
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Patent number: 8722073Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.Type: GrantFiled: June 6, 2013Date of Patent: May 13, 2014Assignee: Howmedica Osteonics Corp.Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
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Publication number: 20140012314Abstract: Cupped forceps are provided. Methods of using a cupped forceps are provided.Type: ApplicationFiled: June 28, 2013Publication date: January 9, 2014Applicant: InVivo Therapeutics CorporationInventors: Haining William Dai, Brian Hess, Francis M. Reynolds, David Kosh, Fioleda Prifti
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Publication number: 20130264244Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.Type: ApplicationFiled: June 6, 2013Publication date: October 10, 2013Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
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Publication number: 20130233736Abstract: A protective packaging with one or more product preparation features is provided.Type: ApplicationFiled: March 11, 2013Publication date: September 12, 2013Applicant: INVIVO THERAPEUTICS CORPORATIONInventors: Brian Hess, Francis M. Reynolds, Edward Wirth, III, John M. Harvey, Celina Chang, Haining Dai, Fioleda Prifti
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Publication number: 20130219868Abstract: The present invention describes a motor designed for biodiesel compatibility comprising a particulate filter, a motor control unit being able to inject fuel to the engine in order to increase the exhaust temperature, and a lubricant composition, characterized in that the lubricant composition comprises at least one ester group containing polymer.Type: ApplicationFiled: October 28, 2011Publication date: August 29, 2013Applicant: Evonik Oil Additives GmbHInventors: Michael Alibert, Thorsten Bartels, Julien Couet, Alexander Dardin, Daniel H. Deneen, Brian Hess, Michael Mueller, Christian Daniel Georges Neveu, Gerhard Renner, Torsten Stoehr, Christoph Wincierz
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Patent number: 8481065Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.Type: GrantFiled: December 16, 2010Date of Patent: July 9, 2013Assignee: Howmedica Osteonics Corp.Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
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Patent number: 8303599Abstract: A stand for use with a syringe is structured to engage a portion of the syringe in order to maintain the syringe in an upright position. The stand may include an aperture structured to engage the nozzle or the plunger of the syringe. Another embodiment of the stand may include a protrusion structured to engage the proximal end of the syringe, or a clip structured to engage a handle of the syringe. The stand may include a package portion having compartments for holding various components, such as components of a bone cement preparation kit. The proximal and distal portions of the barrel of the syringe may be separable to provide an opening into the barrel through which an injectable material may be inserted. The plunger of the syringe may also include a plunger rod removably affixed to the plunger tip.Type: GrantFiled: September 22, 2010Date of Patent: November 6, 2012Assignee: Stryker Leibinger GmbH & Co. KGInventors: Brian Hess, Matthew E. Murphy
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Publication number: 20110296743Abstract: The present invention relates to a fuel composition comprising at least one biodiesel fuel and comprising 0.05 to 5% by weight of at least one polymer comprising ester groups, which comprises repeat units derived from ester monomers having 16 to 40 carbon atoms in the alcohol radical, and repeat units derived from ester monomers having 7 to 15 carbon atoms in the alcohol radical, and the polymer comprising ester groups has a weight-average molecular weight in the range from 5000 to 100 000 g/mol. The present invention further describes the use of polymers comprising ester groups as flow improvers in fuel compositions which comprise at least one biodiesel fuel. Surprising advantages can be achieved especially with regard to the improvement of the cloud point and the low-temperature storability.Type: ApplicationFiled: December 29, 2009Publication date: December 8, 2011Applicant: EVONIK ROHMAX ADDITIVES GMBHInventors: Rene Koschabek, Yann D'Herve, Phil Hutchinson, Brian Hess, Sandra Kuenzel
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Publication number: 20110192076Abstract: The present invention describes a fuel oil composition comprising at least one biodiesel oil and at least one additive for improving the filterability.Type: ApplicationFiled: February 5, 2010Publication date: August 11, 2011Applicant: EVONIK ROHMAX ADDITIVES GMBHInventors: Brian HESS, Robert Cybert, Marie Malitsky, Frank-Olaf Maehling, Rene Koschabek, Ronny Sondjaja
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Publication number: 20110152195Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.Type: ApplicationFiled: December 16, 2010Publication date: June 23, 2011Applicant: Howmedica Osteonics Corp.Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
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Patent number: 7892347Abstract: The invention is related to a premixed putty calcium phosphate composition comprising at least two calcium phosphate minerals, at least one reaction retarding agent, at least one binding agent, at least one sodium phosphate, and at least one nonaqueous extender, wherein one of said at least two calcium phosphate minerals contains a stabilizing agent.Type: GrantFiled: December 17, 2009Date of Patent: February 22, 2011Assignee: Howmedica Osteonics Corp.Inventors: Gerard M. Insley, Adrian Sun Wai, Donal O'Mahony, Paul Higham, Joseph P. Zitelli, Sandra M. Murray, Brian Hess
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Publication number: 20100095870Abstract: The invention is related to a premixed putty calcium phosphate composition comprising at least two calcium phosphate minerals, at least one reaction retarding agent, at least one binding agent, at least one sodium phosphate, and at least one nonaqueous extender, wherein one of said at least two calcium phosphate minerals contains a stabilizing agent.Type: ApplicationFiled: December 17, 2009Publication date: April 22, 2010Inventors: Gerard M. Insley, Adrian Sun Wai, Donal O'Mahony, Paul Higham, Joseph P. Zitelli, Sandra M. Murray, Brian Hess