Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

Abstract: Substituted bicyclic heteroaryls having the structures: and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110? activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemi

Abstract: Systems and methods are described for establishing a connection between a client and a server that are each communicating via a network. The methods and techniques may be used, for example, to establish a media streaming connection between a media player and a placeshifting device when a firewall or other impediment to direct network connections exists. A relay server receives connection requests from the client and from the server via the network. In response to receiving the requests, a first connection is established between the relay server and the client and a second connection between the relay server and the server. Data received by the relay server on each of the first and second connections is relayed to the other of the first and second connections to thereby establish the connection between the client and the server via the relay server.

Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

Abstract: A method of determining whether live media content or time-shifted media content is received at a communication device is presented. In the method, attribute information concerning media content received at a communication device at a specific time is received. Also received is schedule information including an identity of media content carried at the specific time over a channel identified in the attribute information. The media content identity from the attribute information is compared with the media content identity from the schedule information. The received media content is determined to be live media content if the media content identity from the attribute information agrees with the media content identity from the schedule information. The received media content is determined to be time-shifted media content if the media content identity from the attribute information does not agree with the media content identity from the schedule information.

Abstract: A claim pre-processing system employs trial adjudication to improve claim accuracy prior to claim submission to a healthcare payer institution or other entity. A system processes claim data related to provision of healthcare to a patient The system includes a claim data collator for collating data related to a claim for a particular patient for submission to a payer and a source of rules for use in processing collated claim data. A pre-processor submits the collated claim data for processing using the rules to validate the collated claim data is in condition for processing to initiate generation of payment. A claim processor submits the collated claim data to a payer, in response to successful validation by the pre-processor. A rules processor processes acquired claim data to identify a condition triggering application of a different set of rules for determining validity of an individual claim element.

Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity.

Abstract: A hinge assembly for a wireless communication device that pivotally connects a display housing member to a keypad housing member is described. The hinge assembly comprises an upper hinge arm, a lower hinge arm, and a rotating assembly. The upper hinge arm includes an upper hinge plate that is coupled to the display housing member. The lower hinge arm includes a lower hinge plate that is coupled to the keypad housing member. The rotating assembly comprises a first fastener, a second fastener and at least one conductive spring. The first fastener couples the upper hinge arm to one end of the rotating assembly. The second fastener couples the lower hinge arm to the other end of the rotating assembly. At least one conductive spring interfaces with at least one hinge end, and provides a ground path within the hinge assembly.

Abstract: Systems and methods are described for establishing a connection between a client and a server that are each communicating via a network. The methods and techniques may be used, for example, to establish a media streaming connection between a media player and a placeshifting device when a firewall or other impediment to direct network connections exists. A relay server receives connection requests from the client and from the server via the network. In response to receiving the requests, a first connection is established between the relay server and the client and a second connection between the relay server and the server. Data received by the relay server on each of the first and second connections is relayed to the other of the first and second connections to thereby establish the connection between the client and the server via the relay server.

Abstract: A patient claim data processing system responds to and initiates clinical events and attains early accurate claim data during a patient healthcare encounter cycle to support prompt claim data validation and editing both for individual claim elements and for a completed claim to improve claim accuracy prior to claim submission to a payer. The system submits accurate claims to payers and receives remittance advice from payers and applies rules to the advice. A system processes financial data related to provision of healthcare to a patient in response to clinical events. The system includes an interface processor for receiving a message identifying an event and a related change in healthcare data concerning a patient and also includes a source of rules for determining characteristics associated with reimbursement for provision of an individual service to a patient.

Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110? activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lympho

Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

Abstract: The opening area of the vagina contains most of its nerve endings; this area is generally much more sensitive to pressure than the inner two-thirds of the vagina. This portion of the vagina is also more constricted than the inner two-third of the vaginal area. When dilated, such as during a vaginal examination, pressure on and near the vaginal opening may increase pressure upon the adjacent urethral opening and the pubic bone, causing increased discomfort without providing additional expansion of the area. The middle area of the vagina is more dilatable, has fewer nerve endings, and more readily deforms when pressure is applied. The disclosed speculum is intended to place little pressure on the somewhat constricted vaginal opening and allow for increased expansion through the middle area, resulting in less discomfort to the patient during examination and maximized viewing area. A speculum and method of use are disclosed. Embodiments of speculum include upper and lower speculum blades.

Abstract: An automated banking machine that is activated responsive to data read from user cards which accepts checks and dispense cash to users. The automatic banking machine is operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the automatic banking machine in exchange for a deposited check. The automatic banking machine dispenses cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.