Patents by Inventor Brian M. Holmes

Brian M. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210361847
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: August 3, 2021
    Publication date: November 25, 2021
    Applicant: Terumo BCT, Inc.
    Inventors: Thomas J. FELT, Dennis J. HLAVINKA, Brian M. HOLMES
  • Publication number: 20210361849
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: August 3, 2021
    Publication date: November 25, 2021
    Applicant: Terumo BCT, Inc.
    Inventors: Taylor POLODNA, Brian M. HOLMES
  • Publication number: 20210361850
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: August 4, 2021
    Publication date: November 25, 2021
    Applicant: Terumo BCT, Inc.
    Inventors: Brian M. HOLMES, Thomas J. FELT, Taylor POLODNA
  • Publication number: 20210361848
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: August 3, 2021
    Publication date: November 25, 2021
    Applicant: Terumo BCT, Inc.
    Inventors: Peter O'BRIEN, Brian M. HOLMES
  • Patent number: 11110217
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: September 7, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Peter O'Brien, Brian M. Holmes
  • Patent number: 11103630
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 31, 2021
    Assignee: Terumo BCT, Inc
    Inventors: Brian M. Holmes, Thomas J. Felt, Taylor Polodna
  • Patent number: 11103629
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 31, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Taylor Polodna, Brian M. Holmes
  • Patent number: 11090425
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 17, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Thomas J. Felt, Dennis J. Hlavinka, Brian M. Holmes
  • Patent number: 11013851
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 25, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Brian M. Holmes, Thomas J. Felt, Peter O'Brien
  • Publication number: 20180304003
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Taylor POLODNA, Brian M. HOLMES
  • Publication number: 20180304001
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Thomas J. FELT, Dennis J. HLAVINKA, Brian M. HOLMES
  • Publication number: 20180304002
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Brian M. HOLMES, Thomas J. FELT, Taylor POLODNA
  • Publication number: 20180304004
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Brian M. Holmes, Thomas J. Felt, Peter O'Brien
  • Publication number: 20180304000
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicant: Terumo BCT, Inc.
    Inventors: Peter O'BRIEN, Brian M. HOLMES
  • Patent number: 9737898
    Abstract: A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: August 22, 2017
    Assignee: Terumo BCT, Inc.
    Inventors: Brian M. Holmes, James R. Ladtkow
  • Patent number: 9435736
    Abstract: A centrifugal blood separation system comprising a rotor, a light source, an optical sensor, a control system, a separation vessel, and an optical cell on the separation vessel. The optical cell has a first extraction port extending radially outwardly into the optical cell, a red blood cell extraction port downstream from the first extraction port and extending into the optical cell beyond the first extraction port; and a dam between said first extraction port and said red blood cell extraction port, having an upper edge and a lower edge, wherein the first extraction port and the red cell extraction port are radially between the upper edge and the lower edge of the dam. Also, a first extraction port having a bore having a first diameter, a lumen having a second diameter smaller than the first diameter, and a frustro-conical passageway coupling the bore to the lumen.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: September 6, 2016
    Assignee: Terumo BCT, Inc.
    Inventors: Jeremy P. Kolenbrander, Brian M. Holmes, Thomas J. Felt, James R. Ladtkow
  • Publication number: 20150375238
    Abstract: A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.
    Type: Application
    Filed: September 10, 2015
    Publication date: December 31, 2015
    Applicant: TERUMO BCT, INC.
    Inventors: Brian M. HOLMES, James R. LADTKOW
  • Patent number: 9156039
    Abstract: A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.
    Type: Grant
    Filed: June 12, 2012
    Date of Patent: October 13, 2015
    Assignee: Terumo BCT, Inc.
    Inventors: Brian M. Holmes, James R. Ladtkow
  • Patent number: 8992402
    Abstract: A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, and outlet and a side tap outlet adjacent the inlet. The inlet may protrude into the cell separation chamber forming a circumferential well surrounding the protruding inlet. The side tap outlet may connect to the well. The set and system comprise means for selectively drawing fluid from either the outlet or the side tap outlet.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: March 31, 2015
    Assignee: Terumo BCT, Inc.
    Inventor: Brian M. Holmes
  • Patent number: 8900112
    Abstract: A method for controlling a centrifuge blood component separation system for separating components of a blood product, the separation system comprising a centrifuge and a separation bag and at least one transfer bag. The method comprises selecting a nominal hematocrit value such that an actual hematocrit value is expected to be less than said nominal hematocrit; centrifuging a separation bag containing a volume of composite liquid so as to cause the sedimentation of at least a first component and a second component; transferring some of the first component to a first transfer bag; detecting time of passage of a red blood cell interface at a pre-selected location in the separation bag; and adjusting a predicted processing time based on the time of passage of the red blood cell interface.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: December 2, 2014
    Assignee: Terumo BCT, Inc.
    Inventors: Brian M. Holmes, Briden Ray Stanton, Geert Van Waeg, Mary Langley