Abstract: A clamp kit and method for removably connecting a vehicle to a load cell in a wind tunnel can include a clamp module, at least one extension and a third fastener. The clamp module can include first and second jaws, a drive member, and a clamp fastener. The clamp fastener can be connected to the second jaw. The at least one extension can include first and second fasteners. The clamp module can be connected to a post member to form a first configuration clamp when the third fastener is directly connected to both of the clamp fastener and a fastener of the post member, and the clamp module and the extension can be connected to the post member to form a second configuration clamp when the first fastener is directly connected to the clamp fastener and the second fastener is directly connected to the fastener of the post member.

Abstract: A metal hybrid additive manufacturing apparatus includes a melted metal drop ejecting device and at least one other tool that are operated to form metal objects on a platform. An object heater is configured to direct heat toward the metal object being formed on the platform. The object heater can be a radiation heater, a convection heater, an infrared heater, an induction heater, and a focused energy source. The focused energy source can be integrated with the melted metal drop ejecting device.

Abstract: A docking mechanism incorporates a melted metal drop ejecting device within a subtractive manufacturing system to form a metal hybrid manufacturing system. The docking mechanism includes connectors for coupling a supply of melted metal and electrical controls to the melted metal drop ejecting device for operation of the device.

Abstract: A metal hybrid manufacturing apparatus includes a melted metal drop ejecting device and a metal deposition device. The melted metal drop ejecting device is operated to form perimeters of layers in a metal object being formed by the system. The metal deposition device is operated to fill interior portions of the layers.

Abstract: The invention provides solid forms of 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl) propan-2-amine salt for example, Form 1 or Form 2; as well as pharmaceutical compositions, and the uses thereof in treating diseases, conditions or disorders modulated by GLP-1R in a mammal, such as a human.

Abstract: Adaptive clock mechanisms for serial links utilizing a delay-chain-based edge generation circuit to generate a clock that is a faster (higher-frequency) version of an incoming digital clock. The base frequency of the link clock utilized by the line transmitters is determined by the (slower) clock utilized by the digital circuitry supplying data to the line transmitters. An edge generator that may be composed of only non-synchronous circuit elements multiplies the edges of the slower clock to generate the link clock and also a clock forwarded to the receiver at a phase offset from the link clock.

Abstract: Vector-scaled hierarchical codebook quantization reduces precision (bitwidth) vectors of parameters and may enable energy-efficient acceleration of deep neural networks. A vector (block array) comprises one or more parameters within a single dimension of a multi-dimensional tensor (or kernel). For example, block array comprises 4 sub-vectors (blocks) and each sub-vector comprises 8 parameters. The parameters may be represented in integer, floating-point, or any other suitable format. A vector cluster quantization technique is used to quantize blocks of parameters in real-time. Hardware circuitry within a datapath identifies an optimal codebook of a plurality of codebooks for quantizing each block of parameters and the block is encoded using the identified codebook. During processing, the identified codebook is used to obtain the quantized parameter and perform computations at the reduced precision.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for machine learning. One of the methods includes receiving a message; parsing the message to identify individual sentences within the message; encoding each sentence into a vector that represents a semantic meaning of the sentence; applying one or more classification models to the message including: providing each vector to a machine learning model, wherein the machine learning model is trained to generate a prediction of one or more classifications for each sentence of the message; generating a predicted classification for the message as a whole; and determining a message routing based on the predicted classification.

Abstract: Solid forms of (S)-2-(5-((3-ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide, including crystalline forms and an amorphous form, in addition to pharmaceutical compositions, processes for preparing, and their use to treat diseases, conditions and disorders modulated by the activity of the diacylglycerol acyltransferase 2 (DGAT2) in a mammal such as a human are described herein.

Abstract: Techniques described herein include assessing factors that may affect the quality of software under development by a development team or that may be used to evaluate the health of software already deployed in a computing environment. In one example, this disclosure describes a method that includes collecting, by a computing system, historical information about a plurality of prior development projects; correlating, by the computing system, the historical information with each of a plurality of developers that participated in one or more of the plurality of prior development projects; collecting, by the computing system, information about an application developed by a subset of the plurality of developers; generating, by the computing system and based on the information about the application and the correlated historical information, a predicted outcome for the application; and taking an action, by the computing system and based on the predicted outcome, to prevent the predicted outcome.

Abstract: Provided are systems and methods for registration of location sensors. In one aspect, a system includes an instrument and a processor configured to provide a first set of commands to drive the instrument along a first branch of the luminal network, the first branch being outside a path to a target within a model. The processor is also configured to track a set of one or more registration parameters during the driving of the instrument along the first branch and determine that the set of registration parameters satisfy a registration criterion. The processor is further configured to determine a registration between a location sensor coordinate system and a model coordinate system based on location data received from a set of location sensors during the driving of the instrument along the first branch and a second branch.

Abstract: The invention provides synthetic methods for the preparation of cantharidin and analogs thereof. In one aspect, the invention provides an improved Diels-Alder cycloaddition to generate a key intermediate en route to cantharidin and analogs thereof. In certain embodiments, the new Diels-Alder reaction involves reacting Compound (2) in the presence of furan, and in the absence of acid or increased pressure, in an aprotic polar solvent with slight warming, to yield Compound (1) in favorable yield and exo-endo ratio. In another aspect, the invention also provides a new Diels-Alder reaction between compounds of Formula (III) and furan to yield compounds of Formula (IV), which can then be transformed into cantharidin or analogs thereof. In yet another aspect, the invention describes a new palladium-mediated carbonylation providing another key intermediate en route to cantharidin and analogs thereof. In addition to synthetic methods, present invention also provides compounds (i.e.

Abstract: An interface in accordance with present embodiments includes a base and a theme portion disposed on the base. A first layer is disposed on the base and includes a mixture with metallic powder suspended within a translucent medium. A second layer is disposed on the base over the first layer and over the theme portion, and includes the mixture. A third layer is disposed on the base and on the theme portion over only portions of the second layer. The third layer includes paint and paint thinner. A fourth layer is disposed on the theme portion over the third layer and exposed portions of the second layer. The fourth layer also includes the mixture.

Abstract: A vacuum pump comprises an inlet flange for connecting to a vacuum chamber, where the inlet flange comprises a plurality of apertures for receiving a plurality of protruding fixing elements extending from the vacuum chamber. The protruding fixing elements comprise an enlarged retaining portion at an end remote from the vacuum chamber and a fastener receiving portion having at least one radial dimension that is smaller than a corresponding dimension of the enlarged retaining portion. A fastening mechanism is provided that comprises a plurality of slots each extending from a same side of a plurality of apertures. The fastening mechanism is configured to be rotatable between a mounting position in which the apertures are aligned with the protruding fixing elements and a sealing position in which the slots are aligned with the protruding fixing elements.

Abstract: In order to reduce oscillations in process variables of an injection molding process, an injection molding machine may be operatively connected to a model database that stores models of injection molding machines and molds. A tuning controller may set initial gain values of a variable-gain proportional-integral-derivative (PID) controller. To set the initial gains, the tuning controller may be configured to obtain, from the model database, a model for a first and second injection molding machines and a model for a mold. The tuning controller may analyze the models to determine a correlation between injection molding machine parameters and mold cycle performance for the mold. Accordingly, the tuning controller may apply the correlation to determine an initial gain value for a least one of the first, second, and third gains of the PID controller. The tuning controller may then set the initial gain values for the PID controller.

Abstract: In order to improve the consistency of molded products as viscosity shifts throughout a run, a controller of an injection molding machine executes a calibration cycle in accordance with a mold cycle. The controller analyzes a plurality of sensed melt pressure values during the calibration cycle to determine one or more calibration metrics. The controller then uses the calibration metrics when executing each mold cycle of the run. More particularly, during each mold cycle of the run, the controller detects a plurality of sensed melt pressures prior to and during a fill phase of the mold cycle and compares the plurality of sensed melt pressures to the one or more calibration metrics to predict cavity pressure for a pack and hold phase of the mold cycle. The controller then adjusts a set point pressure for the pack and hold phase based on the predicted cavity pressure.

Abstract: Systems and methods describe supplementing a “native controller” of an injection molding with a remote controller, via a retrofitting of the remote controller the injection molding machine. The remote controller may thereby modify control of an injection molding process based upon a control strategy of the remote controller, e.g., by providing a modified feedback signal to be used by a control algorithm of the native controller in lieu of a feedback signal previously used by the native controller. The remote controller may generate the “modified feedback signal” based upon its own control algorithm and control strategy. Furthermore, the remote controller may be configured to robustly account for behavior of the native controller so as to provide stable control of a control variable of the process according to a setpoint defined by the remote controller.

Abstract: A system for evaluating the effectiveness of an anti-counterfeiting measure employed for an item is provided. The system trains a classifier to indicate whether the anti-counterfeiting measure of an evaluation item is genuine or counterfeit. For evaluation items that have been classified as genuine or counterfeit, the system applies the classifier to determine whether the anti-counterfeiting measure of that evaluation item is genuine or counterfeit. The system then generates an effectiveness metric that indicates whether the anti-counterfeiting measure is effective based on evaluation items that are assessed as being genuine whose anti-counterfeiting measures are classified as being counterfeit.

Abstract: The present invention discloses a novel p-toluenesulfonic acid salt and a crystalline polymorphic Form 1 of said salt of 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one, pharmaceutical composition containing the same, as well as preparations and uses thereof. The present invention also discloses a novel phosphoric acid salt of 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one, pharma-ceutical composition containing the same, as well as preparations and uses thereof.

Abstract: In order to reduce oscillations in process variables of an injection molding process, an injection molding machine may be operatively connected to a model database that stores models of injection molding machines and molds. A tuning controller may set initial gain values of a variable-gain proportional-integral-derivative (PID) controller. To set the initial gains, the tuning controller may be configured to obtain, from the model database, a model for a first and second injection molding machines and a model for a mold. The tuning controller may analyze the models to determine a correlation between injection molding machine parameters and mold cycle performance for the mold. Accordingly, the tuning controller may apply the correlation to determine an initial gain value for a least one of the first, second, and third gains of the PID controller. The tuning controller may then set the initial gain values for the PID controller.