Abstract: The disclosure is directed to an all glass method that frustrates the internal reflection on the outside diameter of an optical fiber's glass cladding thus allowing the light to be directed to a light absorbing material/ medium and allowing the desired light in the core of the fiber to be preserved with no loss. The frustration is achieved by having at least one glass frustrater in glass-to-glass contact with the outermost cladding layer of the optical fiber. The glass frustrater is made of a glass that has a glass transition point lower that both the core and cladding glasses of the fiber. Chalcogenide and phosphate glasses are among the glasses suitable for this application.

Abstract: The present invention is directed to pharmaceutical compositions containing active compounds, which inhibit the activity of the chemokines, MIP-1? and RANTES. It also is directed to methods of treating inflammatory and immunoregulatory disorders and diseases using these pharmaceutical compositions.

Abstract: A scoreboard clock having a front face including a plurality of display areas arranged to represent a scoreboard, indicia disposed adjacent each of the display areas, and a time means for generating chronological information elements and displaying the elements in the display areas. Each indicia indicates a selected information element related to a selected sporting event that is not related to the chronological information elements being displayed in the display areas.

Abstract: Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Abstract: The subject invention provides a unique system and method that facilitates mitigating the number of versions of a coded application needed to accommodate different spoken languages. The invention involves generating resource tables including resource identifier-resource type pairs. Examples of resource types include strings, bitmaps, icons, menus, and the like. For instance, instead of coding the application with strings, the application is coded with resource identifiers. The strings corresponding to the resource identifiers can be extracted from a resource table and in particular, from a resource file. Before searching through resource files and subdirectories, a cache can be searched to determine whether the resource identifier-string was previously requested. Resource identifiers can be parsed and the relevant information taken therefrom to locate the corresponding strings. If not already in the cache, the resource identifier-string pairs can be cached in a hash table or other database.

Abstract: The subject invention provides a unique system and method that facilitates classifying UI components abstracted from a computer based application in a strongly-typed manner based at least in part from a strongly-typed class framework. Methods included in the strongly-typed classes within the framework can correspond to one or more UI components found in the application. The UI components can be abstracted out and then the closest match between a UI component and a strongly-typed class in the framework can be found. Classes in the framework can be modified to create new strongly-typed classes. Once the UI components are classified in a strongly-typed manner, code can be created, albeit a lesser amount of code than otherwise would be required since the new strongly-typed classes can be derived from the framework.

Abstract: Compounds and compositions are provided that bind to the CXCR3 chemokine receptor and which are useful for treating diseases associated with CXCR3 activity, such as multiple sclerosis.

Abstract: Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Abstract: The invention is directed to the use of energetic ion bombardment, in vacuum, to a surface of a metal fluoride crystal or optical element to remove contaminants on the surface and/or in micro-fractures. After cleaning, a suitable inert dielectric or metallic material is deposited onto the cleaned surface. A sealing agent is then applied to the inert material and a holder is placed about the entire assembly to hold and seal the metal fluoride element within the assembly. The method of the invention, and adhesion layer materials used in conjunction with the method, can be applied to glass elements as well as to metal fluoride single crystals and optical elements made from such crystals.

Abstract: The present invention is directed to pharmaceutical compositions containing active compounds, which inhibit the activity of the chemokines, MIP-1&agr; and RANTES. It also is directed to methods of treating inflammatory and immunoregulatory disorders and diseases using these pharmaceutical compositions.

Abstract: The present invention is directed to pharmaceutical compositions containing active compounds, which inhibit the activity of the chemokines, MIP-1 &agr; and RANTES. It also is directed to methods of treating inflammatory and immunoregulatory disorders and diseases using these pharmaceutical compositions.

Abstract: A scanning system and method of data reading in which the scanning system is provided with a mounting mechanism having the ability to flex and/or rotate when subjected to external mechanical shock for reducing shock experienced by the more delicate scanning components.