Patents by Inventor Brian Wong

Brian Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-ROR1 CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20180147271
    Abstract: The invention provides improved compositions for adoptive cell therapies for cancers that express ROR1.
    Type: Application
    Filed: May 17, 2016
    Publication date: May 31, 2018
    Inventors: Richard MORGAN, Robert SIKORSKI, Brian WONG, Emma MASTELLER, Luis BORGES, Cheng LIU, Yiyang XU
  • ANTI-ROR1 ANTIBODIES
    Publication number: 20180142016
    Abstract: The invention relates to antibodies, and in particular, to antibodies exhibiting specificity for Receptor tyrosine kinase-like Orphan Receptors (ROR), and to uses thereof, for example in the treatment of cancer. The invention extends to polynucleotide and polypeptide sequences encoding the antibodies, and therapeutic uses thereof, and to diagnostic kits comprising these molecules. The invention also extends to antibody-drug conjugates and to uses thereof in therapy.
    Type: Application
    Filed: May 17, 2016
    Publication date: May 24, 2018
    Inventors: Brian WONG, Emma MASTELLER, Cheng LIU, Yiyang XU, Hong LIU, Su YAN, Jingyi XIANG, Pei WANG
  • Biocatalytic process for preparing eslicarbazepine and analogs thereof
    Patent number: 9963683
    Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: May 8, 2018
    Assignee: Codexis, Inc.
    Inventors: Anupam Gohel, Derek J. Smith, Brian Wong, Joly Sukumaran, Wan Lin Yeo, Steven J. Collier, Scott Novick
  • ANTI-CSF1R ANTIBODY AND ANTI PD-1 ANTIBODY COMBINATION THERAPY FOR CANCER
    Publication number: 20180094067
    Abstract: Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
    Type: Application
    Filed: August 18, 2017
    Publication date: April 5, 2018
    Applicants: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Brian Wong, Julie Hambleton, Robert Sikorski, Emma Masteller, Kevin Hestir, David Bellovin, Katherine E. Lewis
  • COMBINATION THERAPY FOR CANCER
    Publication number: 20180085472
    Abstract: Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with one or more immune stimulating agents are provided.
    Type: Application
    Filed: April 12, 2016
    Publication date: March 29, 2018
    Applicant: Five Prime Therapeutics, Inc.
    Inventors: Emma Masteller, Thomas Brennan, David Bellovin, Kevin Baker, Brian Wong
  • SLAMF1 ANTAGONISTS AND USES THEREOF
    Publication number: 20180016555
    Abstract: Methods of identifying and using SLAMF1 antagonists are provided.
    Type: Application
    Filed: October 21, 2015
    Publication date: January 18, 2018
    Applicant: Five Prime Therapeutics, Inc.
    Inventors: Luis Borges, Nathan Sallee, Charles Kaplan, Arthur Brace, W. Michael Kavanaugh, Brian Wong, David Bellovin, Thomas Brennan, Artur Karasyov
  • COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY
    Publication number: 20170298054
    Abstract: The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.
    Type: Application
    Filed: June 29, 2017
    Publication date: October 19, 2017
    Applicant: Rigel Pharmaceuticals, Inc.
    Inventors: Hui Li, Sambaiah Thota, David Carroll, Ankush Argade, Kin Tso, Arvinder Sran, Jeffrey Clough, Holger Keim, Somasekhar Bhamidipati, Vanessa Taylor, Robin Cooper, Rajinder Singh, Brian Wong
  • Anti-CSFR1 antibody and anti PD-1 antibody combination therapy for cancer
    Patent number: 9765147
    Abstract: Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: September 19, 2017
    Assignees: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Brian Wong, Julie Hambleton, Robert Sikorski, Emma Masteller, Kevin Hestir, David Bellovin, Katherine E. Lewis
  • Techniques For Protecting Security Features of Integrated Circuits
    Publication number: 20170257222
    Abstract: An integrated circuit includes a control circuit, a one-time programmable circuit, and a security feature. The control circuit determines if the one-time programmable circuit is programmed in response to a request by a user of the integrated circuit to access the security feature. The control circuit generates a signal to indicate to the user of the integrated circuit that the security feature has been previously accessed if the control circuit determines that the one-time programmable circuit has been programmed to indicate a previous access to the security feature. The control circuit causes the one-time programmable circuit to be programmed in response to the request if the control circuit determines that the one-time programmable circuit has not been programmed.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 7, 2017
    Applicant: Altera Corporation
    Inventors: Bruce Pedersen, Ting Lu, Brian Wong, Alok Doshi, Yun Sum Wong
  • Compositions and methods for inhibition of the JAK pathway
    Patent number: 9732073
    Abstract: The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: August 15, 2017
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Hui Li, Sambaiah Thota, David Carroll, Ankush Argade, Kin Tso, Arvinder Sran, Jeffrey Clough, Holger Keim, Somasekhar Bhamidipati, Vanessa Taylor, Robin Cooper, Rajinder Singh, Brian Wong
  • Sternal Retractor
    Publication number: 20170224322
    Abstract: Devices and methods for sternal retraction that reduces bleeding from the cut edges of a sternum and reduces fracturing of the sternum during retraction. The devices and methods involve the use of sternal retractor blades having a certain geometry and inserts placed inside the sternal retractor blades during retraction of the sternotomy incision. The blades and inserts act to tamponade the blood flow from the cut sternal edge and reduce fracturing of the sternum during retraction.
    Type: Application
    Filed: February 20, 2017
    Publication date: August 10, 2017
    Inventors: John D. Puskas, Kelly Kloster Hon, Erick Eladio Rio, Brian Wong-Shui, Mark Joseph Moneypenny
  • BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF
    Publication number: 20170159028
    Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Inventors: Anupam Gohel, Derek J. Smith, Brian Wong, Joly Sukumaran, Wan Lin Yeo, Steven J. Collier, Scott Novick
  • Biocatalytic process for preparing eslicarbazepine and analogs thereof
    Patent number: 9605290
    Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: March 28, 2017
    Assignee: Codexis, Inc.
    Inventors: Anupam Gohel, Derek J. Smith, Brian Wong, Joly Sukumaran, Wan Lin Yeo, Steven J. Collier, Scott Novick
  • Sternal retractor
    Patent number: 9572561
    Abstract: Devices and methods for sternal retraction that reduces bleeding from the cut edges of a sternum and reduces fracturing of the sternum during retraction. The devices and methods involve the use of sternal retractor blades having a certain geometry and inserts placed inside the sternal retractor blades during retraction of the sternotomy incision. The blades and inserts act to tamponade the blood flow from the cut sternal edge and reduce fracturing of the sternum during retraction.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: February 21, 2017
    Assignee: EMORY UNIVERSITY
    Inventors: John D. Puskas, Kelly Kloster Hon, Erick Eladio Rios, Brian Wong-Shui, Mark Joseph Moneypenny
  • Stepladder with Latch Stud and Method
    Publication number: 20170044827
    Abstract: A stepladder includes a front section having a first front leg and a second front leg. The stepladder includes a step attached to the first front leg and the second front leg. The stepladder includes a latch engaged with the step. The stepladder includes a rear section having a first rear leg and a second rear leg and a cross bar attached to the first rear leg and the second rear leg. The rear section is pivotably attached to the front section. The rear section has a first stud which extends from the first rear leg toward the second rear leg and separate and apart and not in contact with the second rear leg and not in contact with the cross bar.
    Type: Application
    Filed: November 2, 2016
    Publication date: February 16, 2017
    Applicant: Werner Co.
    Inventors: Thomas W. Parker, Brian Wong-Shui, Devin Lee Moore, Christian M. Otis, Erick E. Rios
  • METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R)
    Publication number: 20160326254
    Abstract: Methods of reducing cytokine levels and methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating inflammatory conditions, such as rheumatoid arthritis.
    Type: Application
    Filed: May 13, 2016
    Publication date: November 10, 2016
    Inventors: Brian Wong, Emma Masteller, Kris Reedquist
  • Stepladder with latch stud and method
    Patent number: 9488002
    Abstract: A stepladder includes a front section having a first front leg and a second front leg. The stepladder includes a step attached to the first front leg and the second front leg. The stepladder includes a latch engaged with the step. The stepladder includes a rear section having a first rear leg and a second rear leg and a cross bar attached to the first rear leg and the second rear leg. The rear section is pivotably attached to the front section. The rear section has a first stud which extends from the first rear leg toward the second rear leg and separate and apart and not in contact with the second rear leg and not in contact with the cross bar.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: November 8, 2016
    Assignee: Werner Co.
    Inventors: Thomas W. Parker, Brian A. Wong Shui, Devin Lee Moore, Christian M. Otis, Erick E. Rios
  • METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R)
    Publication number: 20160319028
    Abstract: Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating rheumatoid arthritis and associated conditions, methods of treating systemic lupus erythematosus and associated conditions, and methods of treating multiple sclerosis.
    Type: Application
    Filed: May 11, 2016
    Publication date: November 3, 2016
    Inventors: Brian Wong, Emma Masteller, Justin Wong, Haishan Lin
  • BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF
    Publication number: 20160244792
    Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.
    Type: Application
    Filed: May 10, 2016
    Publication date: August 25, 2016
    Inventors: Anupam Gohel, Derek J. Smith, Brian Wong, Joly Sukumaran, Wan Lin Yeo, Steven J. Collier, Scott Novick
  • Biocatalytic process for preparing eslicarbazepine and analogs thereof
    Patent number: 9365878
    Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: June 14, 2016
    Assignee: Codexis, Inc.
    Inventors: Anupam Gohel, Derek J. Smith, Brian Wong, Joly Sukumaran, Wan Lin Yeo, Steven J. Collier, Scott Novick