Patents by Inventor Brian (Xi-Yu) Guo

Brian (Xi-Yu) Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TISSUE MAPPING AND TREATMENT
    Publication number: 20250099169
    Abstract: Methods, systems, and devices are described for mapping and treating tissue during a medical procedure. In some cases, a device includes a mesh of wires with sensors coupled thereto. The device can be coupled to an expandable treatment element. The expandable treatment element can include multiple segments. The sensors can be used to map a tissue area and monitor the tissue during a medical procedure.
    Type: Application
    Filed: May 1, 2024
    Publication date: March 27, 2025
    Inventors: Brian Schuler, David Bernstein, David G. Matsuura, Phillip J. Simpson
  • Patient Support Systems And Methods For Assisting Caregivers With Patient Care
    Publication number: 20250099312
    Abstract: A patient support system comprises a patient support apparatus for patients. The patient support apparatus comprises a base and a patient support surface supported by the base. The patient support apparatus also comprises powered devices that perform one or more predetermined functions on the patient support apparatus. Multiple input devices are employed to control the powered devices. The input devices are designed to enable caregivers to cause operation of the powered devices, as needed, while freeing the caregivers to perform other tasks.
    Type: Application
    Filed: December 10, 2024
    Publication date: March 27, 2025
    Applicant: Stryker Corporation
    Inventors: William D. Childs, Connor F. St. John, Brian J. Tessmer, Krishna S. Bhimavarapu
  • OPHTHALMIC FORMULATIONS AND METHODS OF USE
    Publication number: 20250099524
    Abstract: Feline herpesvirus (FHV-1) is a highly contagious virus affecting domestic and wild felines and is the leading cause of corneal disease and conjunctivitis in cats. Thus, provided herein is topical ophthalmic formulation for treating FHV-1, comprising L-lysine and a second therapeutic agent, such as osha root (e.g., ligustilide). The formulation enables direct and concentrated delivery to the ocular surface, which is believed to enhance efficacy in treating herpesvirus infections. This innovative approach improves treatment outcomes by targeting the virus more effectively at the site of infection.
    Type: Application
    Filed: September 26, 2024
    Publication date: March 27, 2025
    Inventor: Brian A. Hunter
  • METHODS FOR SYNTHESIZING ALEUTIANAMINE AND ANALOGS THEREOF
    Publication number: 20250099443
    Abstract: Disclosed herein are analogs and derivatives of aleutianamine and methods of making the same. Also disclosed herein are methods of treating pancreatic cancer comprising administration of aleutianamine or its analogs.
    Type: Application
    Filed: September 13, 2024
    Publication date: March 27, 2025
    Inventors: Hao Yu, Zachary P. Sercel, Samir P. Rezgui, Jonathan Farhi, Brian M. Stoltz, Scott C. Virgil
  • Method For Repairing Defects In Metal Structures
    Publication number: 20250100091
    Abstract: A method for repairing a crack in ships or other structures that includes adhesively applying fiber reinforced metal matrix composite tape across the crack of the structure to reduce propagation of the crack and provide additional structural stability until the crack can be permanently repaired.
    Type: Application
    Filed: March 5, 2024
    Publication date: March 27, 2025
    Inventors: Brian L. Gordon, Brandon J. Coates
  • BICYCLE WHEEL HUB, BICYCLE DRIVE TRAIN AND METHODS FOR THE USE THEREOF
    Publication number: 20250100648
    Abstract: A bicycle wheel hub includes a driver rotatable about an axis at a first rotational speed, wherein the driver includes a mating feature configured to engage a cassette. A shell is rotatable about the axis at a second rotational speed. A non-adjustable gear train is coupled between the driver and the shell, wherein the gear train defines a single fixed gear ratio greater than 1:1 between the driver and the shell. A bicycle drive train includes a drive unit having a user input component rotatable about a first axis at a first rotational speed, a chain ring rotatable about a second axis at a second rotational speed, and a gear train coupled between the user input component and the chain ring. The gear train defines a gear ratio less than 1:1 between the user input component and the chain ring. A method of propelling a bicycle is also provided.
    Type: Application
    Filed: September 27, 2023
    Publication date: March 27, 2025
    Applicant: SRAM, LLC
    Inventors: CHRISTOPHER SHIPMAN, BRIAN JORDAN, ANTHONY MEDAGLIA
  • OLIGO-MEDIATED DEPOSITION OF FUNCTIONAL MOLECULES FOR SPATIALLY RESOLVED GENOMICS, TRANSCRIPTOMICS, AND PROTEOMICS
    Publication number: 20250101511
    Abstract: Disclosed are methods and kits for detecting and visualizing biomolecules of interest, RNA molecules, and/or genomic loci, as well as the proteins, RNAs, or chromatin loci associated with the biomolecules of interest, RNA molecules, or genomic loci. The methods and kits can be used for elucidating molecular interactions in situ.
    Type: Application
    Filed: January 13, 2023
    Publication date: March 27, 2025
    Inventors: David SHECHNER, Brian BELIVEAU, Shreeram AKILESH, Sahar ATTAR, Conor CAMPLISSON, Evan KANIA, Ashley TSUE
  • SYSTEMS AND METHODS RELATING TO OBJECT PROTECTION
    Publication number: 20250104086
    Abstract: A method for object protection identification is provided. The method may: monitor, using a processor, at least one of audio data or history data associated with a user; detect an object replacement triggering event, based on a result of the monitoring; receive user data for a user associated with the at least one of audio data or history data; identify an object corresponding to the object replacement triggering event based on the user data; identify object-related information, the object-related information including at least one of an object protection information or an object replacement information; and transmit the at least one of the object protection information or the object replacement information based on identifying the object-related information.
    Type: Application
    Filed: September 25, 2023
    Publication date: March 27, 2025
    Applicant: Capital One Services, LLC
    Inventors: Jeremy GOODSITT, Galen RAFFERTY, Samuel SHARPE, Anh TRUONG, Brian BARR, Grant EDEN, Austin WALTERS
  • METHODS AND COMPOSITIONS FOR MODULATING SPLICING
    Publication number: 20250101016
    Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.
    Type: Application
    Filed: February 27, 2024
    Publication date: March 27, 2025
    Inventors: Michael LUZZIO, Brian LUCAS, Tiansheng WANG, Jun FENG
  • SYSTEMS AND METHODS FOR BUILDING AND USING A FALSE ALARM PREDICTING MODEL TO DETERMINE WHETHER TO ALERT A USER AND/OR RELEVANT AUTHORITIES ABOUT AN ALARM SIGNAL FROM A SECURITY SYSTEM
    Publication number: 20250104552
    Abstract: Systems and methods for building and using a false alarm predicting model to determine whether to alert a user and/or relevant authorities about an alarm signal from a security system are provided. Such systems and methods can include a learning module receiving the alarm signal and additional information associated with the alarm signal, using the false alarm predicting model to process a combination of the alarm signal and the additional information to determine whether the combination represents a false alarm or a valid alarm, and transmitting a status signal indicative of whether the combination represents the false alarm or the valid alarm to an automated dispatcher module, and the automated dispatcher module using the status signal to automatically determine whether to alert the user and/or the relevant authorities about the alarm signal.
    Type: Application
    Filed: December 6, 2024
    Publication date: March 27, 2025
    Applicant: Ademco Inc.
    Inventors: Brian Beale, Sharath Venkatesha, Soumitri Kolavennu, Nathaniel Kraft
  • COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF
    Publication number: 20250101031
    Abstract: The invention features compounds (e.g., macrocyclic compounds) capable of modulating biological processes, for example through binding to a presenter protein (e.g., a member of the FKBP family, a member of the cyclophilin family, or PIN1) and a target protein such as CEP250. These compounds bind endogenous intracellular presenter proteins, such as the FKBPs or cyclophilins, and the resulting binary complexes selectively bind and modulate the activity of the target protein. Formation of a tripartite complex among the presenter protein, the compound, and the target protein is driven by both protein-compound and protein-protein interactions, and both are required for modulation of target protein activity.
    Type: Application
    Filed: April 18, 2024
    Publication date: March 27, 2025
    Inventors: Gregory Lawrence VERDINE, Brian Roger Bowman, Mathew Edward Sowa, Joshua Alan Van Dyke Blodgett, Keith Earl Robison, Dylan Talbot Stiles, Jay Paul Morgenstern, Sharon Ann Townson, Uddhav Kumar Shigdel
  • Fan Casing with Defined Belt Pocket
    Publication number: 20250101992
    Abstract: A fan assembly has a propeller with a plurality of fan blades and a fan power system including a driven sheave on a fan shaft connected to a drive sheave with a drive belt. The propeller is mounted within a fan shroud having an inner surface facing the propeller such that a tip clearance is formed between outer tips of the fan blades and the inner surface. The fan shroud has a belt pocket located on a circumferential path of the propeller, the belt pocket extending away from the inner surface and having a pocket floor that is offset from the inner surface and sized to allow the drive belt to fit between the outer tip of one of the plurality of fan blades and the pocket floor.
    Type: Application
    Filed: September 23, 2024
    Publication date: March 27, 2025
    Inventors: Joshua Sander, Laszlo Talaber, Brian Daniel Duke
  • METHODS AND SYSTEMS FOR CONTROLLING AN ION MOBILITY SEPARATOR BASED ON A HADAMARD ALGORITHM
    Publication number: 20250102464
    Abstract: A pulse control system may obtain, for each ion pulse included in a plurality of ion pulses, a signal acquired by a mass analyzer for ions ejected from a distinct set of channels of an ion mobility separator having a plurality of channels and determine, based on the signals for the plurality of ion pulses and a Hadamard algorithm, a signal associated with the ions ejected from a channel of the ion mobility separator.
    Type: Application
    Filed: September 25, 2023
    Publication date: March 27, 2025
    Inventor: Brian D. Adamson
  • WELL FRACTURE SYSTEMS AND METHODS
    Publication number: 20250101844
    Abstract: A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.
    Type: Application
    Filed: November 25, 2024
    Publication date: March 27, 2025
    Applicant: FMC Technologies, Inc.
    Inventors: Tep Ungchusri, Philippe Espinasse, Jean-Luc Streiff, Gary Bernard, Brian Swagerty, Johann Rongau, Sunil Dutt, Dan Fink, Justin Taylor, James Cook
  • DELIVERY SYSTEMS FOR CARDIAC VALVE REPAIR DEVICES, AND ASSOCIATED METHODS OF OPERATION
    Publication number: 20250099241
    Abstract: Delivery systems for implanting cardiac valve repair devices are disclosed herein. In some embodiments, a delivery system for implanting a valve repair device includes a delivery catheter, an implant shaft, a drive shaft, a clip cable, and a cinching line. The delivery catheter can hold the device in a compressed configuration. The implant shaft can have a hub assembly releasably coupled to a portion of the device, and the drive shaft can be actuated to release the portion of the device from the hub assembly. The clip cable can be releasably coupled to a clip of the device for opening and closing the clip to capture and secure a portion of a native leaflet. The cinching line can extend around a portion of the device for cinching the device to a compressed position when deployed from within the delivery catheter.
    Type: Application
    Filed: September 26, 2024
    Publication date: March 27, 2025
    Inventors: Neil Zimmerman, Brian Y. Tachibana, Matthew McLean, III, Robert O’Grady, Jose Gonzalez, Erik Thai
  • ALLOY COMPOSITIONS AND ARTICLES FORMED OF SUCH COMPOSITIONS
    Publication number: 20250101546
    Abstract: Described herein are compositions, and more particularly to alloy compositions, methods of using the alloy compositions, and articles formed from with the alloy compositions. The alloy compositions are broadly applicable in applications requiring superalloys, including welding processes, additive manufacturing processes, metal casting processes, coating processes, repairing processes, powder metallurgy, and/or combinations thereof.
    Type: Application
    Filed: September 26, 2023
    Publication date: March 27, 2025
    Inventors: Yan Cui, Matthew Joseph Laylock, Michael Douglas Arnett, Jon C. Schaeffer, Brian Lee Tollison
  • ORDER CANCELLATION
    Publication number: 20250104130
    Abstract: A trading platform and trading method that allows access to additional pools of liquidity is described. Other embodiments are also described.
    Type: Application
    Filed: December 10, 2024
    Publication date: March 27, 2025
    Inventors: Howard W. Lutnick, Dean P. Alderucci, Andrew Fishkind, Brian L. Gay, Kevin Foley, Mark Miller, Charles Plott
  • FLEXIBLE INTERPOSER
    Publication number: 20250105131
    Abstract: The present invention provides for an interposer subassembly that is suitable for an electronic system having at least one integrated circuit (1C) component. The interposer subassembly comprises a flexible base layer, having a first surface and an opposing second surface, at least one active electronic circuit component, operatively integrated within said flexible base layer, and at least one first patterned contact layer, provided on any one of said first surface and said second surface of said flexible base layer and which is configured to operably interface with said at least one active electronic circuit component and the at least one 1C component.
    Type: Application
    Filed: December 6, 2024
    Publication date: March 27, 2025
    Inventors: Brian COBB, Scott WHITE, Ken WILLIAMSON, Anthony SOU, Catherine RAMSDALE, Rob MANN, Neil DAVIES, Joao de OLIVEIRA, Gillian EWERS, Pascaline BOULANGER, Richard PRICE
  • MEDICAL DEVICE SYSTEM AND METHOD FOR PREPARING A DOSE
    Publication number: 20250099331
    Abstract: A medical device system including a first container and a second container, the first container including a first container outer body defining a first interior space connected to a first opening of the first container; and a first container-side valve configured to be activated, upon connection of the second container to the first container, from a normally closed position into the first interior space to an activated position, and the second container including a second container outer body defining a second container interior space and a stem fluidly connected to the second container interior space, wherein, upon connection of the second container to the first container, the first container-side valve is configured to be brought into contact with the stem and the stem is configured to activate the first container-side valve from the normally closed position to the activated position.
    Type: Application
    Filed: December 27, 2022
    Publication date: March 27, 2025
    Applicant: BLUEROCK THERAPEUTICS LP
    Inventors: Peter ALDRIDGE, Philippe MARCHAND, Ibrahim DOMIAN, Anna M GALEA, Gregory POLLIERI, Angel Leonardo GUERRERO PALACIO, Brian MAC GIOLLA RI, Jonathan RUBIANTO, Matthew Gardner MAHER, Michael SCOTT
  • SYSTEMS, DEVICES, AND METHODS FOR EXTRACORPOREAL REMOVAL OF CARBON DIOXIDE
    Publication number: 20250099657
    Abstract: Systems, devices, and methods are provided for removing carbon dioxide from a target fluid, such as, for example, blood, to treat hypercarbic respiratory failure or another condition. A device is provided including first and second membrane components for removing dissolved gaseous carbon dioxide and bicarbonate from the fluid, which can be done simultaneously. The device can be in the form of a cartridge configured for use in a dialysis system. A method of treatment is also provided, involving drawing blood from a patient and bringing the patient's blood in contact with a first membrane component having a sweep gas passing therethrough, and a second membrane component having a dialysate passing therethrough. The dialysate's composition can be selected such that charge neutrality is maintained.
    Type: Application
    Filed: December 10, 2024
    Publication date: March 27, 2025
    Inventors: Steven Paul KELLER, Brian Yale CHANG, Jayon WANG