Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: Nitro oleic acid and related metabolites are agonists of PPAR-?. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-?, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-?.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.

Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Abstract: Disclosed is a method for alleviating the oxidative impairment of vascular function by inhibiting the activity of xanthine oxidase, or active forms thereof. Xanthine oxidase levels have been shown to be increased by a variety of conditions, including sickle cell disease. In the present disclosure, allopurinol is used to inhibit xanthine oxidase activity. As a result of the inhibition of xanthine oxidase, .NO levels in a subject can be maintained. In addition to sickle cell disease, allopurinol inhibition of xanthine oxidase may be used to treat other conditions, including, but not limited to, respiratory distress, kidney disease, liver disease, ischemia-reperfusion injury, organ transplant, sepsis, burns, viral infections and hemorrhagic shock.

Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Abstract: The present invention relates to a method of delivering antioxidants to cells and tissues and to compositions suitable for use therein. The invention also relates to methods of disease treatment involving the use of such compositions.

Abstract: An apparatus is disclosed for measuring the diffusion of hydrogen atoms from a second surface to a first surface of a ferrous metal body as a means of measuring the magnitude of corrosion occurring at the second surface. The apparatus comprises a chamber-defining member which can be sealed to the first surface of the body so as to define with the first surface a sealed chamber. The chamber-defining member is constructed of material sufficiently flexible that upon evacuation of the sealed chamber the chamber-defining member deflects toward the first surface to reduce the chamber volume. The apparatus provides a connecting means for attaching an evacuating pump which is used to evacuate substantially all of the contents of the chamber.

Abstract: An apparatus for measuring the diffusion of hydrogen atoms from a second surface to a first surface of a ferrous metal body in order to monitor the magnitude of corrosion occurring at the second surface. The apparatus comprises a chamber-defining member which can be sealed to the first surface of the body so as to define with the first surface a sealed chamber. The chamber-defining member is constructed of material sufficiently flexible that upon evacuation of the sealed chamber the chamber-defining member deflects toward the first surface to reduce the chamber volume. The apparatus provides a connection for attaching an evacuating pump which is used to evacuate substantially all of the contents of the chamber. A valve is provided to isolate the evacuated chamber from the evacuation pump so that hydrogen atoms, generated as a result of corrosion of the second surface, migrate through the body and exit the first surface within the chamber and combine to form hydrogen molecules which collect in the chamber.

Abstract: An apparatus and process for applying thermoplastic adhesive in a dot pattern to flexible die-cut parts, such as shoe parts. The apparatus includes a tank with a removable bottom and heating elements within the removable bottom of the tank, a mixing roll, an applicator roll having a pattern of indentations over the entire surface, a primary wiper, a secondary wiper, a pressure roll and a number of stripping fingers which ride in grooves in the applicator roll.

Abstract: An apparatus and process for applying thermoplastic adhesive in a dot pattern to flexible die-cut parts, such as shoe parts. The apparatus includes a tank with a removable bottom and heating elements within the removable bottom of the tank, a mixing roll, an applicator roll having a pattern of indentations over the entire surface, a primary wiper, a secondary wiper, a pressure roll and a number of stripping fingers which ride in grooves in the applicator roll.

Abstract: This invention relates to a beverage dispensing system which includes a base container, an elongated discharge neck detachably connectable to the base container and a pouring spout or nozzle which is provided for snap engaging the open outer end of the neck. The nozzle or spout includes a liquid discharge channel and an air vent channel positioned in close proximity to the liquid discharge channel and extending substantially parallel thereto.