Patents by Inventor Bruce Branchaud

Bruce Branchaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240010657
    Abstract: Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
    Type: Application
    Filed: July 10, 2023
    Publication date: January 11, 2024
    Inventors: Lai-Qiang YING, Stephen YUE, Bruce BRANCHAUD, Yu-Zhong ZHANG
  • Patent number: 11731982
    Abstract: Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: August 22, 2023
    Inventors: Lai-Qiang Ying, Bruce Branchaud, Yu-Zhong Zhang, Stephen Yue
  • Publication number: 20210395184
    Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Applicants: Complexa, Inc., University of Pittsburgh - of the Commonwealth System of Higher Education, Life Technologies Corporation
    Inventors: Bruce A. Freeman, Bruce Branchaud
  • Publication number: 20210269767
    Abstract: Methods for increasing the stability of, or protecting, labile components, such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium, are described. Stability of the labile compound is increased either, by derivatization or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule or by the use of sequestering agents. Encapsulation can provide controlled release of the susceptible compound being protected. These methods may improve or extend the storage conditions, the shipping and handling of media compositions comprising the labile compounds at room temperature rather than at lower temperatures, thereby decreasing shipping costs.
    Type: Application
    Filed: May 4, 2021
    Publication date: September 2, 2021
    Inventors: Richard FIKE, Bruce BRANCHAUD, Shawn BARRETT
  • Patent number: 11028361
    Abstract: Methods for increasing the stability of, or protecting, labile components such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium. Stability of the labile compound is increased either, by derivatization of the labile compound with chemicals, or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule, or by the use of sequestering agents. Encapsulation includes the encapsulation of dendrimers complexes of susceptible compounds within the microcapsule, thereby providing the controlled release of the susceptible compound that was protected. These methods may improve and extend storage conditions of compositions comprising the labile compounds, improve shipping and handling of compositions comprising the labile compounds, such as dry media formulations, at room temperature rather than at lower temperatures thereby decreasing shipping costs.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: June 8, 2021
    Assignee: Life Technologies Corporation
    Inventors: Richard Fike, Bruce Branchaud, Shawn Barrett
  • Publication number: 20200308096
    Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
    Type: Application
    Filed: October 31, 2019
    Publication date: October 1, 2020
    Applicants: COMPLEXA, INC., UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, LIFE TECHNOLOGIES CORPORATION
    Inventors: Bruce A. FREEMAN, Bruce BRANCHAUD
  • Publication number: 20200190465
    Abstract: Methods for increasing the stability of, or protecting, labile components such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium. Stability of the labile compound is increased either, by derivatization of the labile compound with chemicals, or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule, or by the use of sequestering agents. Encapsulation includes the encapsulation of dendrimers complexes of susceptible compounds within the microcapsule, thereby providing the controlled release of the susceptible compound that was protected. These methods may improve and extend storage conditions of compositions comprising the labile compounds, improve shipping and handling of compositions comprising the labile compounds, such as dry media formulations, at room temperature rather than at lower temperatures thereby decreasing shipping costs.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Inventors: Richard FIKE, Bruce BRANCHAUD, Shawn BARRETT
  • Patent number: 10669522
    Abstract: Methods for increasing the stability of, or protecting, labile components, such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium, are described. Stability of the labile compound is increased either, by derivatization or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule or by the use of sequestering agents. Encapsulation can provide controlled release of the susceptible compound being protected. These methods may improve or extend the storage conditions, the shipping and handling of media compositions comprising the labile compounds at room temperature rather than at lower temperatures, thereby decreasing shipping costs.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: June 2, 2020
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Richard Fike, Bruce Branchaud, Shawn Barrett
  • Publication number: 20190322681
    Abstract: Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
    Type: Application
    Filed: March 27, 2019
    Publication date: October 24, 2019
    Inventors: Lai-Qiang YING, Bruce BRANCHAUD, Yu-Zhong ZHANG, Stephen YUE
  • Publication number: 20190041332
    Abstract: Methods, systems and reagents are provided for detecting and quantifying carbonyl containing moieties in a variety of sample types.
    Type: Application
    Filed: July 31, 2018
    Publication date: February 7, 2019
    Inventors: Gerald Thomas, Charles Noll, Juven Lara, Brian Young, Craig Carlsen, Bruce Branchaud, James Ingle
  • Publication number: 20180202936
    Abstract: The present invention is directed to compounds, compositions, methods, and kits for detecting reactive oxygen species (ROS) by conventional fluorescence microscopy, fluorescence spectroscopy, flow cytometry, and/or high content imaging. The compounds disclosed herein are novel reduced dyes, including Cy-based hydrocyanine dyes and Cy-based deuterocyanine dyes, which dyes are probes for detecting ROS and measuring oxidative stress in cells either in vitro and/or in vivo. Also described herein are processes for preparing novel reduced dyes, i.e., ROS probes, for use in the disclosed compositions, methods and kits.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 19, 2018
    Inventors: Hee Chol Kang, Kyle Gee, Bhaskar Mandavilli, Lai-Qiang Ying, Bruce Branchaud
  • Patent number: 9867795
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: January 16, 2018
    Assignees: The UAB Research Foundation, The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Publication number: 20170369419
    Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
    Type: Application
    Filed: September 7, 2017
    Publication date: December 28, 2017
    Applicants: Complexa, Inc., University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Bruce A. FREEMAN, Bruce BRANCHAUD
  • Patent number: 9828453
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: November 28, 2017
    Assignees: Life Technologies Corporation, Life Technologies AS
    Inventors: Nini Hofslokken Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven M. Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
  • Patent number: 9790167
    Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: October 17, 2017
    Assignees: COMPLEXA, INC., UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Bruce A. Freeman, Bruce Branchaud
  • Publication number: 20170174700
    Abstract: Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
    Type: Application
    Filed: December 27, 2016
    Publication date: June 22, 2017
    Inventors: Lai-Qiang YING, Bruce BRANCHAUD, Yu-Zhong ZHANG, Stephen YUE
  • Publication number: 20170119717
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: November 21, 2016
    Publication date: May 4, 2017
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Patent number: 9567346
    Abstract: Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: February 14, 2017
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Lai-Qiang Ying, Bruce Branchaud, Yu-Zhong Zhang, Stephen Yue
  • Patent number: 9522156
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: December 20, 2016
    Assignees: The UAB Research Foundation, The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Publication number: 20160326291
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Application
    Filed: July 18, 2016
    Publication date: November 10, 2016
    Inventors: Nini Hofslokken KJUS, Geir FONNUM, Bruce BRANCHAUD, Lai-Qiang YING, Steven M. MENCHEN, Dmitriy GREMYACHINSKIY, Hee Chol KANG