Patents by Inventor Bruce Branchaud

Bruce Branchaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9422384
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: August 23, 2016
    Assignees: Life Technologies Corporation, Life Technologies AS
    Inventors: Nini Hofslokken Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven M. Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
  • Publication number: 20160151391
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: February 10, 2016
    Publication date: June 2, 2016
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Patent number: 9295678
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: March 29, 2016
    Assignees: The UAB Research Foundation, The State of Oregon Acting By And Through The State Board Of Higher Education On Behalf of The University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Publication number: 20150284496
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Application
    Filed: June 22, 2015
    Publication date: October 8, 2015
    Inventors: Nini Hofslokken KJUS, Geir FONNUM, Bruce BRANCHAUD, Lai-Qiang YING, Steven M. MENCHEN, Dmitriy GREMYACHINSKIY, Hee Chol KANG
  • Publication number: 20150246059
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: March 4, 2015
    Publication date: September 3, 2015
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Publication number: 20150183754
    Abstract: Fatty acid inhibitors, pharmaceutical compositions including fatty acid inhibitors, methods for using fatty acid inhibitors to treat a variety of diseases, and methods for preparing fatty acid inhibitors are provided herein.
    Type: Application
    Filed: March 12, 2015
    Publication date: July 2, 2015
    Inventor: Bruce BRANCHAUD
  • Patent number: 9067954
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: June 30, 2015
    Assignees: Life Technologies Corporation, Life Technologies AS
    Inventors: Nini H. Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven M. Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
  • Patent number: 9062079
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: June 23, 2015
    Assignee: Life Technologies Corporation
    Inventors: Nini Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
  • Patent number: 9061903
    Abstract: A nanoparticle having one or more phosphonates or phosphinate ligands on their surface can be converted into nanoparticles with sulfonate ligands on their surface, by contacting the phosphonate-containing nanoparticles with a silylsulfonate reagent. Such nanoparticles are activated toward reactions with nucleophilic groups; thus the method provides activated nanoparticles, and methods of making and using them to produce modified nanoparticles.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: June 23, 2015
    Assignee: Life Technologies Corporation
    Inventors: Eric Tulsky, Eric Welch, Bruce Branchaud, John Mauro, Imad Naasani
  • Patent number: 9062080
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: June 23, 2015
    Assignees: Life Technologies Corporation, Life Technologies AS
    Inventors: Nini H. Kjus, Geir Fonnum, Bruce Branchaud, Lai-Qiang Ying, Steven M. Menchen, Dmitriy Gremyachinskiy, Hee Chol Kang
  • Patent number: 9006473
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: April 14, 2015
    Assignees: The UAB Research Foundation, The State of Oregon Acting By and Through the State Board of Higher Education on Behalf of The University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Patent number: 8901333
    Abstract: Coated fluorescent semiconductor nanoparticles having an organic surface layer of multi-functional surface ligands that include a nanocrystal binding center and one or more covalently attached functional groups or reactive functional groups are described as well as water-dispersible nanoparticles having an organic surface layer or multi-functional surface ligands and methods for the preparation and use of such coated nanoparticles.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: December 2, 2014
    Assignee: Life Technologies Corporation
    Inventors: Eric Tulsky, Eric Welch, Bruce Branchaud, Roman Rozhkov
  • Publication number: 20140080966
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 20, 2014
    Applicants: LIFE TECHNOLOGIES AS, LIFE TECHNOLOGIES CORPORATION
    Inventors: Nini H. KJUS, Geir FONNUM, Bruce BRANCHAUD, Lai-Qiang Ying, Steven M. MENCHEN, Dmitriy GREMYACHINSKIY, Hee Chol KANG
  • Publication number: 20140073756
    Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 13, 2014
    Applicants: LIFE TECHNOLOGIES AS, LIFE TECHNOLOGIES CORPORATION
    Inventors: Nini H. KJUS, Geir FONNUM, Bruce BRANCHAUD, Lai-Qiang Ying, Steven M. MENCHEN, Dmitriy GREMYACHINSKIY, Hee Chol KANG
  • Publication number: 20130316004
    Abstract: Methods for increasing the stability of, or protecting, labile components such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium. Stability of the labile compound is increased either, by derivatization of the labile compound with chemicals, or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule, or by the use of sequestering agents. Encapsulation includes the encapsulation of dendrimers complexes of susceptible compounds within the microcapsule, thereby providing the controlled release of the susceptible compound that was protected. These methods may improve and extend storage conditions of compositions comprising the labile compounds, improve shipping and handling of compositions comprising the labile compounds, such as dry media formulations, at room temperature rather than at lower temperatures thereby decreasing shipping costs.
    Type: Application
    Filed: February 7, 2012
    Publication date: November 28, 2013
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Richard Fike, Bruce Branchaud, Shawn Barrett
  • Publication number: 20130287689
    Abstract: The present invention is directed to compounds, compositions, methods, and kits for detecting reactive oxygen species (ROS) by conventional fluorescence microscopy, fluorescence spectroscopy, flow cytometry, and/or high content imaging. The compounds disclosed herein are novel reduced dyes, including Cy-based hydrocyanine dyes and Cy-based deuterocyanine dyes, which dyes are probes for detecting ROS and measuring oxidative stress in cells either in vitro and/or in vivo. Also described herein are processes for preparing novel reduced dyes, i.e., ROS probes, for use in the disclosed compositions, methods and kits.
    Type: Application
    Filed: November 1, 2011
    Publication date: October 31, 2013
    Applicant: Life Technologies Corporation
    Inventors: Hee Chol Kang, Kyle Gee, Bhaskar Mandavilli, Lai-Qiang Ying, Bruce Branchaud
  • Publication number: 20130261099
    Abstract: Fatty acid inhibitors, pharmaceutical compositions including fatty acid inhibitors, methods for using fatty acid inhibitors to treat a variety of diseases, and methods for preparing fatty acid inhibitors are provided herein.
    Type: Application
    Filed: May 24, 2013
    Publication date: October 3, 2013
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventor: Bruce BRANCHAUD
  • Publication number: 20130210917
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Application
    Filed: October 8, 2012
    Publication date: August 15, 2013
    Applicants: THE UAB RESEARCH FOUNDATION, Morehouse School of Medicine, Inc., University College Cardiff Consultants Limited, State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Patent number: 8470879
    Abstract: Fatty acid inhibitors, pharmaceutical compositions including fatty acid inhibitors, methods for using fatty acid inhibitors to treat a variety of diseases, and methods for preparing fatty acid inhibitors are provided herein.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: June 25, 2013
    Assignee: Life Technologies Corporation
    Inventor: Bruce Branchaud
  • Publication number: 20130012583
    Abstract: Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 10, 2013
    Applicants: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, COMPLEXA, INC.
    Inventors: Bruce A. FREEMAN, Bruce BRANCHAUD