Abstract: The present invention relates to isolated Porphorymonas gingivalis polypeptides and nucleotides. The polypeptides include; an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; or an amino acid sequence at least 85%, preferably at least 95%, identical to an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; or at least 40 amino acids having a contiguous sequence of at least 40 amino acids identical to a contiguous amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532.

Abstract: A scalable process for purification of phosphorodiamidite includes steps of solubilizing a crude phosphorodiamidite in an apolar organic solvent, contacting the non-polar organic solvent with a polar phase comprising a polar organic solvent to remove impurities from the solubilized phosphorodiamidite, and removing the non-polar organic solvent from the phosphorodiamidite.

Abstract: A process of purifying phosphoramidite precursors useful in inter alia synthesis of oligonucleotides comprises dissolving a crude phosphoramidite in a polar phase, adding a basic compound to the polar phase, adding a portion of water to the polar phase, contacting the polar phase with a first apolar phase to extract impurity into the apolar phase, separating the first apolar phase from the polar phase, adding a second aliquot of water to the polar phase, and contacting the polar phase with a second apolar phase, whereby the phosphoramidite partitions into the second apolar phase.

Abstract: A set of tools for the process generally known as “paintless dent repair” for removing a class of dents in automobile body panels is modified to have interchangeable handles with a range of positions relative to the working end of the tool. Thus, permitting the modified set of tools to be comprised of many fewer individual tools than is the current practice in the art.

Abstract: A small form factor smart card has a card body with a first end having structure for attachment to a keychain or other tether, and a second end carrying an embedded chip. Locking structure is on the card body for cooperation with locking structure associated with a card reader/writer for holding the card in place in the reader/writer during an operation. In a preferred embodiment, the locking structure associated with the card reader/writer is carried by an adaptor that is inserted into a slot of the reader/writer, and the card is inserted into a slot of the adaptor.

Abstract: Oligonucleotide analogs are disclosed having pyrimidine monomeric sub-units therein that are modified at eh 2? and 5? positions. Monomeric sub-units having these modifications may be further modified at the 2? position. Improved processes for the synthesis of 2?-O-substituted pyrimidine nucleosides are also provided. The processes feature alkylation of a 2,2?-anhydropyrimidine nucleoside or a 2S,2?-anhydropyrimidine nucleoside with a weak nucleophile in the presence of a Lewis acid.

Abstract: A relational processor having multiple inputs for receiving and processing parallel words. The relational processor comprises one or more input subsections for converting parallel input data to serial output data. Each of the one or more subsections has a parallel input for receiving the parallel input data and a respective subsection output for outputting the serial output data. A plurality of Boolean processors process the serial output data into processed output data, which plurality of Boolean processors are each operatively connected to the subsection outputs of the one or more input subsections to receive the serial output data. The processed output data is routed with a data routing system which is connected to a processor output of each of the plurality of Boolean processors to route data therefrom to one or more destination Circuits. The relational processor processes the input data in a single pass.

Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting therefrom.

Abstract: A process of purifying phosphoramidite precursors useful in inter alia synthesis of oligonucleotides comprises dissolving a crude phosphoramidite in a polar phase, adding a basic compound to the polar phase, adding a portion of water to the polar phase, contacting the polar phase with a first apolar phase to extract impurity into the apolar phase, separating the first apolar phase from the polar phase, adding a second aliquot of water to the polar phase, and contacting the polar phase with a second apolar phase, whereby the phosphoramidite partitions into the second apolar phase.

Abstract: A scalable process for purification of phosphorodiamidite includes steps of solubilizing a crude phosphorodiamidite in an apolar organic solvent, contacting the non-polar organic solvent with a polar phase comprising a polar organic solvent to remove impurities from the solubilized phosphorodiamidite, and removing the non-polar organic solvent from the phosphorodiamidite.

Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting therefrom.

Abstract: A method and apparatus of run-length compression is disclosed where a contiguous stream of bits is input to a compression circuit. The contiguous stream of bits is analyzed in sets of a fixed number of bits, the sets of bits analyzed successively using one or more comma codes each having a respective bit code and a variable length compression operator. Select ones of the one or more comma codes are applied to each set of bits based upon the length of the run of similar bits of the contiguous stream of bits. An encoded stream of bits is output in a single pass with the compression circuit using the one or more comma codes, the encoded stream having fewer bits than the contiguous stream of bits and comprising one or more of the bit codes and respective variable length operators.

Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting therefrom.

Abstract: A single contiguous memory buffer is disclosed having at least first and second memory spaces in the memory buffer each functioning as a FIFO. When operating the memory buffer in a first mode, the first memory space functions as an input structure for loading of the one or more words, and the second memory space functions as an output structure for unloading of the one or more words. When operating the memory buffer in a second mode, the first memory space functions as the output structure for unloading of the one or more words, and the second memory space functions as the input structure for loading of the one or more words. A flip signal is used to toggle between the first and second modes to operate the first and second memory spaces. The respective sizes of the memory spaces vary dynamically according to whether the buffer memory is operating in the first mode or the second mode.

Abstract: A transaction system includes the use of a fixed data structure that allows multiple point-of-sale systems to recognize and access a transaction card regardless of upper level user interfaces. More specifically, a smart card includes a memory with a defined data file structure, wherein the data file structure includes at least one read only field, at least one encrypted read/write field, and at least one non-encrypted read/write field. The read only field preferably includes at least one of a manufacturer identification field, a card identification field and a theater identification field. The encrypted read/write field preferably includes at least one of a transaction log field, an issue date field, a first dollar value field, a second dollar value field, a first point value field, a second point value field and a ticket storage field.

Abstract: A method of relational processing is disclosed where a query of one or more databases of records returns the query result in the form of one or more threads of parallel words. A collection generator generates one or more intermediate vectors of serial bit streams from the one or more threads, and processes the one or more intermediate vectors with a relational processor. The relational processor is operable to perform one or more logical operations thereon in a single pass, and outputs a contiguous serial bit stream.

Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting there-from.

Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting therefrom.

Abstract: For large scale preparation of pyrimidine ribonucleosides, the intermediate 2-O-methyl-(or ethyl)-1,3,5-tri-O-benzoyl-.alpha.-D-ribose can be prepared using a diazomethane (or diazoethane) reaction that is controlled via an inert solvent transferring system. This transfer system allows for large scale preparations of the pyrimidine ribonucleosides.