Patents by Inventor Bruno Domon

Bruno Domon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CTNB1 AS A MARKER FOR ENDOMETRIAL CANCER
    Publication number: 20240011994
    Abstract: Present invention provides a method for diagnosing and prognosing endometrial cancer in easy-to-access isolated samples by detecting the level of expression of one or more proteins. In particular from uterine fluid samples. The invention also provides kits comprising means for detecting said proteins for use in the diagnosis and prognosis of the disease.
    Type: Application
    Filed: June 15, 2023
    Publication date: January 11, 2024
    Inventors: Elena MARTINEZ GARCÍA, Eva COLÁS ORTEGA, Antonio GIL MORENO, Jaume REVENTÓS PUIGJANER, Bruno DOMON, Antoine LESUR, Irene CAMPOY MONCAYO
  • MARKERS OF ENDOMETRIAL CANCER
    Publication number: 20230221323
    Abstract: The present invention provides a method of diagnosis or prognosis endometrial carcinoma, the method comprising determining the level of expression of MMP9 in a uterine aspirate fluid sample from the female genital tract. The present invention further provides kits for the diagnosis of the disease.
    Type: Application
    Filed: November 9, 2022
    Publication date: July 13, 2023
    Inventors: Elena MARTINEZ GARCÍA, Eva COLÁS ORTEGA, Antonio GIL MORENO, Jaume REVENTÓS PUIGJANER, Bruno DOMON, Antoine LESUR
  • Bladder cancer biomarker proteins
    Patent number: 11536724
    Abstract: The invention relates to a collection of signature peptides representing at least 10 proteins for use in cancer diagnosis and/or prognosis, to an artificial protein comprising signature peptides representing at least 10 proteins and to a nucleic acid construct encoding for such an artificial protein. The invention further relates to a collection of at least 10 proteins for use in cancer diagnosis and/or prognosis. Additionally, the invention relates to a method for cancer diagnosis and/or prognosis comprising the step of analyzing at least 10 proteins in a urine sample of a subject. Finally, the invention relates to an immunoassay product comprising antibodies for detecting at least 10 proteins.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: December 27, 2022
    Assignees: POLYQUANT GMBH, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS, LUXEMBOURG INSTITUTE OF HEALTH, INSTITUT CURIE, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III, CNIO
    Inventors: Jerome Garin, Christophe Masselon, Antonia Vlahou, Manousos Makrydakis, Ieronimos Zoidakis, Bruno Domon, Elodie Duriez, Aurelie Kamoun, Francois Radvanyi, Yves Allory, Nuria Malats Riera, Mirari Marquez Cid, Magali Court
  • COLON DISEASE TARGETS AND USES THEREOF
    Publication number: 20200325189
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.
    Type: Application
    Filed: January 16, 2020
    Publication date: October 15, 2020
    Inventors: Bruno DOMON, Aiqun LI, Tao HE, Ian MCCAFFREY
  • METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
    Publication number: 20200276329
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Application
    Filed: January 8, 2020
    Publication date: September 3, 2020
    Inventors: Steve RUBEN, Karen VAN ORDEN, Bruno DOMON, Candy LEE, Tao HE, Mehdi MESRI, Elizabeth JOSELOFF, Katherine MCKINNON, Paul MOORE, Charles BIRSE
  • CTNB1 AS A MARKER FOR ENDOMETRIAL CANCER
    Publication number: 20200264183
    Abstract: Present invention provides a method for diagnosing and prognosing endometrial cancer in easy-to-access isolated samples by detecting the level of expression of one or more proteins. In particular from uterine fluid samples. The invention also provides kits comprising means for detecting said proteins for use in the diagnosis and prognosis of the disease.
    Type: Application
    Filed: July 20, 2018
    Publication date: August 20, 2020
    Inventors: Elena MARTINEZ GARCÍA, Eva COLÁS ORTEGA, Antonio GIL MORENO, Jaume REVENTÓS PUIGJANER, Bruno DOMON, Antoine LESUR, Irene CAMPOY MONCAYO
  • PANCREATIC CANCER TARGETS AND USES THEREOF
    Publication number: 20200116726
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
    Type: Application
    Filed: July 24, 2019
    Publication date: April 16, 2020
    Inventors: Bruno Domon, Ian McCaffrey, Vaibhav Narayan, Scott Patterson
  • Markers of Endometrial Cancer
    Publication number: 20190137499
    Abstract: The present invention provides a method of diagnosis or prognosis endometrial carcinoma, the method comprising determining the level of expression of MMP9 in a uterine aspirate fluid sample from the female genital tract. The present invention further provides kits for the diagnosis of the disease.
    Type: Application
    Filed: March 30, 2017
    Publication date: May 9, 2019
    Applicants: FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'H'EBRON-INSTITUT DE RECERCA, LUXEMBOURG INSTITUTE OF HEALTH (LIH), INSTITUT DE RECERCA BIOMÈDICA DE LLEIDA FUNDACIÓ DR. PIFARRÉ
    Inventors: Elena MARTINEZ GARCÍA, Eva COLÁS ORTEGA, Antonio GIL MORENO, Jaume REVENTÓS PUIGJANER, Bruno DOMON, Antoine LESUR
  • BLADDER CANCER BIOMARKER PROTEINS
    Publication number: 20180372754
    Abstract: The invention relates to a collection of signature peptides representing at least 10 proteins for use in cancer diagnosis and/or prognosis, to an artificial protein comprising signature peptides representing at least 10 proteins and to a nucleic acid construct encoding for such an artificial protein. The invention further relates to a collection of at least 10 proteins for use in cancer diagnosis and/or prognosis. Additionally, the invention relates to a method for cancer diagnosis and/or prognosis comprising the step of analyzing at least 10 proteins in a urine sample of a subject. Finally, the invention relates to an immunoassay product comprising antibodies for detecting at least 10 proteins.
    Type: Application
    Filed: December 23, 2016
    Publication date: December 27, 2018
    Inventors: Jerome GARIN, Christophe MASSELON, Antonia VLAHOU, Manousos MAKRYDAKIS, Ieronimos ZOIDAKIS, Bruno DOMON, Elodie DURIEZ, Aurelie KAMOUN, Francois RADVANYI, Yves ALLORY, Nuria MALATS RIERA, Mirari MARQUEZ CID, Magali COURT
  • COLON DISEASE TARGETS AND USES THEREOF
    Publication number: 20180251502
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.
    Type: Application
    Filed: September 5, 2017
    Publication date: September 6, 2018
    Inventors: Bruno DOMON, Aiqun LI, Tao HE, Ian MCCAFFREY
  • Analyte mass spectrometry quantitation using a universal reporter
    Patent number: 9945867
    Abstract: Quantitation of analytes, including but not limited to peptides, polypeptides, and proteins, in mass spectrometry using a labeled peptide coupled to a reporter, and a universal reporter.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: April 17, 2018
    Assignee: Thermo Fisher Scientific GmbH
    Inventors: Joel Louette, John Charles Rogers, Scott M. Peterman, Bruno Domon, Elodie Duriez
  • METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
    Publication number: 20170350897
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Application
    Filed: April 12, 2017
    Publication date: December 7, 2017
    Inventors: Steve RUBEN, Karen VAN ORDEN, Bruno DOMON, Candy LEE, Tao HE, Mehdi MESRI, Elizabeth JOSELOFF, Katherine MCKINNON, Paul MOORE, Charles BIRSE
  • PANCREATIC CANCER TARGETS AND USES THEREOF
    Publication number: 20170219591
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
    Type: Application
    Filed: December 13, 2016
    Publication date: August 3, 2017
    Inventors: Bruno DOMON, Ian MCCAFFREY, Vaibhav NARAYAN, Scott PATTERSON
  • Methods and compositions for treating and diagnosing diseases
    Patent number: 9658232
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: May 23, 2017
    Assignee: Celera Corporation
    Inventors: Steve Ruben, Bruno Domon, Candy Lee
  • Analyte mass spectrometry quantitation using a universal reporter
    Patent number: 9377469
    Abstract: Quantitation of analytes, including but not limited to peptides, polypeptides, and proteins, in mass spectrometry using a labeled peptide coupled to a reporter, and a universal reporter.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: June 28, 2016
    Assignee: Thermo Fisher Scientific GmbH
    Inventors: Joel Louette, John Charles Rogers, Scott M. Peterman, Bruno Domon, Elodie Duriez
  • METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
    Publication number: 20160161494
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Application
    Filed: June 19, 2015
    Publication date: June 9, 2016
    Inventors: Steve RUBEN, Karen VAN ORDEN, Bruno DOMON, Candy LEE, Tao HE, Mehdi MESRI, Elizabeth JOSELOFF, Katherine MCKINNON, Paul MOORE, Charles BIRSE
  • COLON DISEASE TARGETS AND USES THEREOF
    Publication number: 20160137705
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.
    Type: Application
    Filed: September 22, 2015
    Publication date: May 19, 2016
    Inventors: Bruno DOMON, Aiqun LI, Tao HE, Ian MCCAFFREY
  • ANALYTE MASS SPECTROMETRY QUANTITATION USING A UNIVERSAL REPORTER
    Publication number: 20160097749
    Abstract: Quantitation of analytes, including but not limited to peptides, polypeptides, and proteins, in mass spectrometry using a labeled peptide coupled to a reporter, and a universal reporter.
    Type: Application
    Filed: October 30, 2015
    Publication date: April 7, 2016
    Inventors: Joel Louette, John Charles Rogers, Scott M. Peterman, Bruno Domon, Elodie Duriez
  • Methods and compositions for treating and diagnosing diseases
    Patent number: 9090682
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: July 28, 2015
    Assignee: Celera Corporation
    Inventors: Steve Ruben, Bruno Domon, Candy Lee
  • ANALYTE MASS SPECTROMETRY QUANTITATION USING A UNIVERSAL REPORTER
    Publication number: 20150148260
    Abstract: Quantitation of analytes, including but not limited to peptides, polypeptides, and proteins, in mass spectrometry using a labeled peptide coupled to a reporter, and a universal reporter.
    Type: Application
    Filed: December 22, 2014
    Publication date: May 28, 2015
    Inventors: Joel Louette, John Charles Rogers, Scott M. Peterman, Bruno Domon, Elodie Duriez