Patents by Inventor Bruno Domon

Bruno Domon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
    Publication number: 20100061977
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Application
    Filed: July 17, 2009
    Publication date: March 11, 2010
    Applicant: CELERA CORPORATION
    Inventors: Steve RUBEN, Karen VAN ORDEN, Candy N. LEE, Tao HE, Mehdi MESRI, Elizabeth G. JOSELOFF, Paul MOORE, Katherine MCKINNON, Bruno DOMON
  • Cripto mutant and uses thereof
    Patent number: 7604931
    Abstract: The present invention is based on the discovery that CRIPTO mutants each comprising at least one amino acid substitution from a CRIPTO polypeptide demonstrate tumor blocking activity.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: October 20, 2009
    Assignee: Biogen Idec MA Inc.
    Inventors: Kevin P. Williams, Susan Foley, Susan Schiffer, Bruno Domon, Michele Sanicola-Nadel
  • Methods and compositions for treating and diagnosing disease
    Patent number: 7582441
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: September 1, 2009
    Assignee: Celera Corporation
    Inventors: Steve Ruben, Candy N. Lee, Bruno Domon
  • Methods and compositions for treating diseases targeting CDCP1
    Publication number: 20090196873
    Abstract: Methods and compositions for detecting and treating a disease, particularly cancer, associated with differential expression of CDCP1 in disease cells compared to healthy cells. Also provided are antagonists or agonists of CDCP1, and methods for screening agents that modulate the CDCP1 level or activity in vivo or in vitro.
    Type: Application
    Filed: June 6, 2008
    Publication date: August 6, 2009
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Charles E. Birse, Candy Lee, Steve Ruben
  • Pancreatic cancer targets and uses thereof
    Publication number: 20090138977
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
    Type: Application
    Filed: October 3, 2008
    Publication date: May 28, 2009
    Applicant: CELERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Pancreatic cancer targets and uses thereof
    Patent number: 7473531
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: January 6, 2009
    Assignee: Colora Corporation
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Pancreatic cancer secreted targets and uses thereof
    Publication number: 20080219992
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAST) and antibodies binds to PCAST. The present invention provides that PCAST is used as targets for screening agents that modulates the PCAST activities. Further the present invention provides methods for treating diseases associated with pancreas.
    Type: Application
    Filed: February 13, 2008
    Publication date: September 11, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Kim Alving, Steve Ruben, Ian McCaffery, Bruno Domon
  • Pancreatic cancer secreted targets and uses thereof
    Patent number: 7358231
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAST) and antibodies binds to PCAST. The present invention provides that PCAST is used as targets for screening agents that modulates the PCAST activities. Further the present invention provides methods for treating diseases associated with pancreas.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: April 15, 2008
    Assignee: Applera Corporation
    Inventors: Ian McCaffey, Kim Alving, Bruno Domon, Steven Ruben
  • Selective capture and enrichment of proteins expressed on the cell surface
    Publication number: 20080076907
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Application
    Filed: September 28, 2007
    Publication date: March 27, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Selective capture and enrichment of proteins expressed on the cell surface
    Patent number: 7348416
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: March 25, 2008
    Assignee: Applera Corporation
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Method and compositions for the treating diseases targeting E-cadherin
    Publication number: 20070059757
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
    Type: Application
    Filed: November 13, 2006
    Publication date: March 15, 2007
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Methods and compositions for treating diseases targeting CDCP1
    Publication number: 20070031419
    Abstract: Methods and compositions for detecting and treating a disease, particularly cancer, associated with differential expression of CDCP1 in disease cells compared to healthy cells. Also provided are antagonists or agonists of CDCP1, and methods for screening agents that modulate the CDCP1 level or activity in vivo or in vitro.
    Type: Application
    Filed: June 28, 2006
    Publication date: February 8, 2007
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Charles Birse, Candy Lee, Steve Ruben
  • Selective capture and enrichment of proteins expressed on the cell surface
    Publication number: 20060154332
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Application
    Filed: November 19, 2004
    Publication date: July 13, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Method and compositions for treating diseases targeting CD71
    Publication number: 20060039907
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD71 in comparison to healthy cells. Also provided are antagonists or agonists of CD71, and methods for screening agents that modulate the CD71 level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 23, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Method and compositions for treating diseases targeting CD51
    Publication number: 20060035239
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD51 in comparison to healthy cells. Also provided are antagonists or agonists of CD51, and methods for screening agents that modulate the CD51 level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 16, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Method and compositions for treating diseases targeting E-cadherin
    Publication number: 20060029988
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 9, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Diagnosis of pancreatic cancer by using pancreatic targets
    Publication number: 20060029987
    Abstract: Methods and compositions for diagnosing, detecting a pancreatic disease associated with differential expression of PCATs (e.g., CD49b, CD51, CD71 and E-Cadherin) in comparison to healthy cells.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 9, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Cripto mutant and uses thereof
    Publication number: 20030232755
    Abstract: The present invention is based on the discovery that CRIPTO mutants each comprising at least one amino acid substitution from a CRIPTO polypeptide demonstrate tumor blocking activity.
    Type: Application
    Filed: March 17, 2003
    Publication date: December 18, 2003
    Applicant: BIOGEN, INC.
    Inventors: Kevin P. Williams, Susan Foley, Susan Schiffer, Bruno Domon, Michele Sanicola-Nadel