Abstract: An injection device for injecting medicament in a patient includes a syringe coupled to a housing and radially retained by a retaining rib. A needle guard is slideably coupled to the housing and spring biased in a distal direction by a return spring. A ram is slideably coupled to the housing and spring biased in the distal direction by a main spring. An initial position is defined by a retaining arm being disposed in the longitudinal path of the ram preventing firing. A released position is defined by the retaining arm being clear from the longitudinal path of the ram allowing the ram to extend distally. A locked position is defined by the retaining arm being disposed in the longitudinal path of the ram and a lock arm of the ram being disposed in the longitudinal path of the needle guard preventing the needle guard from being retracted.

Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: An intelligent imaging device determines an occlusion of a shutter mechanism. The shutter mechanism opens to expose light to an image sensor, and the shutter mechanism closes to block the light from entering the image sensor. However, as the shutter mechanism transitions between full open and full close, the shutter mechanism is partially open and exposing the light to the image sensor. The image sensor continues generating images during these transitions, thus possibly revealing personal/sensitive data. The intelligent imaging device determines the shutter mechanism is partially open by conducting a real time, frame-by-frame content analysis. The intelligent imaging device may then disable an interface to the image sensor to avoid sharing personal/sensitive data. Even if the shutter mechanism is manually operated, the intelligent imaging device implements a visual/audible warning to warn a user that the shutter mechanism is not completely open or closed.

Abstract: A dilution refrigerator is provided. The dilution refrigerator includes a plurality of thermalization plates configured to be cooled to a plurality of temperatures, and a first thermalization plate of the plurality of thermalization plates includes an integrated heat exchanger. The integrated heat exchanger includes channels formed in the first thermalization plate, and the channels are configured to allow helium to flow through the first thermalization plate during operation of the dilution refrigerator to improve heat exchange and cooling power of the dilution refrigerator.

Abstract: A head unit system for a head of a user, including a headpiece including a support structure shaped to be worn over the head. A shield mount attached to the support structure is arranged for supporting a face shield adjacent to the head. A headpiece connector is attached to the support structure and has a headpiece contact configured for electrical connection. A peripheral device provided for being secured to the headpiece for concurrent movement, the peripheral device having a device connector with a device contact configured for electrical connection. The device connector and the headpiece connector cooperate to releasably attach the peripheral device to the headpiece in a secured configuration with the respective headpiece contact and the device contact abutting in the secured configuration so as to facilitate electrical connection between the headpiece and the peripheral device.

Abstract: An interface module configured to control a motor in an HVAC system is provided. The interface module includes a processor coupled in communication with a memory. The processor is configured to wirelessly receive configuration data from a wireless device, store the wirelessly received configuration data in the memory, determine a first operating parameter at which to operate the motor based on the configuration data and at least one signal received from a first device, and control the motor in accordance with the first operating parameter.

Abstract: An electronic key may include a partial capacitor comprising a capacitive metal plate in communication with a processor. The capacitive metal plate of the partial capacitor is configured to form a capacitor with a corresponding capacitive metal plate of a lock when brought into proximity with the metal plate of the lock. Data may be transferred from the key to the lock using a capacitor formed by combining the two metal plates, wherein a common ground is established between the metal plate of the key and the metal plate of the lock through a parasitic capacitance present between the key and lock circuitry. Audit trail data may be recorded based on usage of the key.

Abstract: A connection device for fastening two expanded cellular confinement structures includes: an insertion member; an integral shank extending perpendicular from the insertion member; and an integral handle member extending perpendicular from the shank at an end of the shank remote from the insertion member. One or more barbs may project from the insertion member. The device can have a washer section between the handle member and insertion member. The handle can be curved, or it can be in the shape of a polygon.

Abstract: A method for controlling brake pressure during a shift of a vehicle out of park may include determining that a first status condition is met when the vehicle is in park with an electric parking brake applied, determining that a second status condition is met when the vehicle is not moving, responsive to detecting a shift of the vehicle out of park when the first and second status conditions are both met, directing a build-up of brake pressure until a brake pressure target is reached, and holding the brake pressure at the brake pressure target until a release condition is met.

Abstract: Red rust staining of Al/Zn coated steel strip in “acid rain” or “polluted” environments can be minimised by forming the coating as an Al—Zn—Si—Mg alloy coating with an OT:SDAS ratio greater than a value of 0.5:1, where OT is the overlay thickness on a surface of the strip and SDAS is the measure of the secondary dendrite arm spacing for the Al-rich alpha phase dendrites in the coating. Red rust staining in “acid rain” or “polluted” environments and corrosion at cut edges in marine environments can be minimised in Al—Zn—Si—Mg alloy coatings on steel strip by selection of the composition (principally Mg and Si) and solidification control (principally by cooling rate) and forming Mg2Si phase particles of a particular morphology in interdendritic channels.

Abstract: A model validation system is described that is configured to automatically validate model artifacts corresponding to models. For a model artifact being validated, the model validation system is configured to dynamically determine the validation checks to be performed for the model artifact, where the validation checks include various validation checks to be performed at the model artifact level and also for individual components included in the model artifact. The checks to be performed are dynamically determined based upon the attributes of the model artifact and of the components within the model artifact. The system is configured to generate a validation report that comprises information regarding the checks performed and the results generated from performing the various validation checks. The validation report may also include information suggesting actions for passing checks that result in a failed check, or for improving the scores of certain validation checks.

Abstract: A waste disposal system for receiving pharmaceutical waste material including at least one of a solid phase pharmaceutical waste material and a liquid phase pharmaceutical waste material is provided. The waste receiver includes a receiver body defining an opening. The waster receiver further includes an inner surface defining a container volume in fluid communication with the opening, and an outer surface opposite the inner surface. The outer surface defines a lock passageway separate from the opening. The system further includes a bracket adapted to be secured to a fixed surface and a locking assembly coupled to the bracket and adapted to releasably secure the waste receiver to the fixed surface. The locking assembly includes a lock housing sized to be removably positioned at least partially within the lock passageway.

Abstract: The present disclosure provides systems and techniques for an attachment that can be fastened to a gun. The attachment may include a top surface having a longitudinal axis and an aiming sight that is parallel with the longitudinal axis, a front surface having a latitudinal axis that is perpendicular to the longitudinal axis, the front surface including a muzzle aperture, a left surface, a right surface, and a fastening system. The fastening system may include a first mounting aperture of the left surface, a second mounting aperture of the right surface, and a locking pin capable of being positioned in the first mounting aperture and in the second mounting aperture such that the locking pin fastens the attachment to the gun. The attachment may be fastened to the gun such that the longitudinal axis is parallel with a longitudinal bore axis of the gun.

Abstract: Visualization within a spherical space is provided. The method comprises capturing a number of images from a common three-point coordinate capture location and creating a sphere of projected coordinates based on the capture location. Three-point coordinates of reference locations corresponding to the images are translated into spherical coordinates on the sphere. The spherical coordinates of the reference locations are translated into tour scene coordinates. The tour scene coordinates of the reference locations are then translated into equirectangular Cartesian coordinates. The images are displayed in a user interface according to the reference locations from the perspective of the capture location.

Abstract: A Representational State Transfer (REST)-Simple Message Transfer Protocol (SMTP) protocol gateway (RSPG) is disclosed that includes capabilities for accessing and processing REST Application Programming Interfaces (APIs) using SMTP. The RSPG receives a first email message, extracts information from the received first email message and constructs a REST API call based on the extracted information. The RSPG invokes the REST API call against a REST endpoint and receives a response generated from execution of the REST API call. The RSPG generates a second email message based on the response and causes the second email message to be communicated to an intended recipient of the response of the REST API call.

Abstract: A method and apparatus for performing an integrated search is provided. An interface is provided that allows users to search and select any data related to a searchable term. Searchable terms may comprise titles of content, actors, and tags. Upon receiving results from the initial search, the user progresses through the initial search by selecting a result from the initial search and conducting a further search of that selection. The search may progress through many layers of searching in order to find information useful to the user and the user may perform actions based upon results of the search. The search implements a display with two columns, the first column displaying selectable data, and the second column displaying results to the selected data. The search is further customizable based upon a privacy level selected by the user.

Abstract: An exercise device includes an actuator that provides resistance to a user. It further includes a sensor that senses the state of the actuator over time. It further includes an emergency event handler that receives a stream of information from the sensor and determines, based at least in part on the stream of information, a potential occurrence of an emergency condition.

Abstract: This invention relates to bacterial strains, compositions comprising bacterial strains as well as methods and uses of said strains and compositions for preventing or treating illness and/or symptoms associated with a coronavirus in a subject in need thereof.

Abstract: An injection device for injecting medicament in a patient includes a syringe coupled to a housing and radially retained by a retaining rib. A needle guard is slideably coupled to the housing and spring biased in a distal direction by a return spring. A ram is slideably coupled to the housing and spring biased in the distal direction by a main spring. An initial position is defined by a retaining arm being disposed in the longitudinal path of the ram preventing firing. A released position is defined by the retaining arm being clear from the longitudinal path of the ram allowing the ram to extend distally. A locked position is defined by the retaining arm being disposed in the longitudinal path of the ram and a lock arm of the ram being disposed in the longitudinal path of the needle guard preventing the needle guard from being retracted.

Abstract: Systems and methods are disclosed herein for training a control system based on prior audio inputs. The disclosed systems and methods receive a non-lexical or interjectional audio input. State change indications are also received and stored by the system within a predefined period of time starting from the time the system received the audio input. The system then receives a subsequent audio input. If the audio inputs of both the audio input and the subsequent audio input match, and contextual information for the audio input and the subsequent audio input match, the system stores a match association, comprising a confidence factor, for the subsequent audio input to the audio input in the associative data structure. If the confidence factor is greater than a preconfigured confidence level, the system executes one or more functions based on stored state change indications.