Patents by Inventor Burkhard Metzger
Burkhard Metzger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9168342Abstract: The present invention relates to medicament blisters for powder inhalers. The blisters according to the invention contain an inhalable powder comprising a medicament. The blisters are characterized by a reduced permeability for water vapor, which is achieved by decreasing the height of the sealing lacquer layer.Type: GrantFiled: July 24, 2006Date of Patent: October 27, 2015Assignee: Boehringer Ingelheim International GmbHInventors: Burkhard Metzger, Johannes Geser, Hubert Hoelz
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Patent number: 8662076Abstract: The present invention relates to capsules for housing pharmaceutical preparations for powder inhalers with increased medicinal product safety and capsules for pharmaceutical preparations for powder inhalers with improved adaption to use in powder inhalers. The capsules consist of non-water-soluble, hydrophobic plastics, which themselves do not substantially influence the pharmaceutical quality of the contents, but improve the usability of the filled capsules in respect of their operation, the period of use and/or the geographical location of their use and are advantageous in various steps from manufacture to use.Type: GrantFiled: January 6, 2006Date of Patent: March 4, 2014Assignee: Boehringer Ingelheim Pharma GmbH & Co. KGInventors: Torsten Kuehn, Rolf Kuhn, Burkhard Metzger, Hubert Hoelz, Stefan Lustenberger, Herbert Wachtel
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Patent number: 8602024Abstract: The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed as depicted in exemplary FIG. 1. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.Type: GrantFiled: April 13, 2007Date of Patent: December 10, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Herbert Kunze, Achim Moser, Elmar Mock, Antonino Lanci, Andre Klopfenstein
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Patent number: 8563101Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.Type: GrantFiled: March 26, 2010Date of Patent: October 22, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Michael Spallek, Burkhard Metzger
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Patent number: 8561610Abstract: A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5?) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.Type: GrantFiled: May 29, 2012Date of Patent: October 22, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Hubert Kunze, Achim Moser, Elmar Mock, Antonino Lanci, Andre Klopfenstein
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Publication number: 20130248410Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.Type: ApplicationFiled: March 26, 2010Publication date: September 26, 2013Applicant: Boehringer Ingelheim Internation GmbHInventors: Michael SPALLEK, Burkhard METZGER
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Patent number: 8397717Abstract: The present invention relates to an inhaler with a novel mouthpiece having a microbiological protective function. The inhalers are used for administration of a pharmaceutical substance, substance formulation or substance mixture.Type: GrantFiled: October 20, 2006Date of Patent: March 19, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Johannes Geser, Burkhard Metzger
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Publication number: 20120247465Abstract: A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5?) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.Type: ApplicationFiled: May 29, 2012Publication date: October 4, 2012Applicant: Boehringer Ingelheim International GmbHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Hubert Kunze, Achim Moser, Elmar Mock, Antonino Lanci, Andre Klopfenstein
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Patent number: 8267082Abstract: The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips as depicted in exemplary FIGS. 1a and 1b. The medicament chambers have an internal structure (3) which comprises in its interior a space for receiving a powdered medicament and stabilizes this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilizing function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.Type: GrantFiled: April 13, 2007Date of Patent: September 18, 2012Assignee: Boehringer Ingelheim International GmbHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Hubert Kunze, Achim Moser, Elmar Mock, Antonino Lanci, Andre Klopfenstein
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Patent number: 8087286Abstract: In a method for checking the permeability rate of a closed container (3) with respect to a medium, in particular for checking the permeability rate of a film-type container for accommodating a film container for accommodating a pharmaceutical active constituent formulation, the container (3) is filled with a medium, charged with a gas, and the increase in the amount of medium in the gas is then analysed.Type: GrantFiled: July 24, 2006Date of Patent: January 3, 2012Assignee: Boehringer Ingelheim International, GmbHInventors: Daniela Bothe, Hubert Hoelz, Christoph Kreher, Burkhard Metzger, Christian Scheffler
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Patent number: 8001965Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: GrantFiled: February 4, 2009Date of Patent: August 23, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
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Publication number: 20110061652Abstract: The invention relates to a blister for charging an inhaler with a pharmaceutical preparation, characterised in that the blister is at least partially manufactured from a dehydrating plastics material. The invention also relates to blisters according to the invention which are filled with a pharmaceutical preparation.Type: ApplicationFiled: November 18, 2010Publication date: March 17, 2011Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Michael KRUEGER, Burkhard METZGER, Michael TRUNK, Joerg SCHIEWE
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Patent number: 7878193Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: GrantFiled: January 14, 2004Date of Patent: February 1, 2011Assignee: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
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Publication number: 20100327476Abstract: The invention relates to a method for filling a capsule with a pharmaceutical active-substance formulation, wherein the capsule consists of two capsule parts (a capsule body and a capsule cap) and the two capsule parts, without being previously interlocked when empty, are only fitted together in a telescopic manner once one capsule part has been filled with a pharmaceutical active-substance formulation, as well as a device for this purpose.Type: ApplicationFiled: February 7, 2009Publication date: December 30, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Michael Spallek, Burkhard Metzger, Rolf Kuhn, Stefan Lustenberger, Hubert Hoelz, Torsten Kuehn
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Publication number: 20100181225Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.Type: ApplicationFiled: March 26, 2010Publication date: July 22, 2010Applicant: Boehringer Ingelheim Internation GmbHInventors: Michael SPALLEK, Burkhard METZGER
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Patent number: 7758936Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.Type: GrantFiled: September 14, 2004Date of Patent: July 20, 2010Assignee: Boehringer Ingelheim GmbHInventors: Michael Spallek, Burkhard Metzger
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Publication number: 20090250057Abstract: The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips. The medicament chambers have an internal structure (3) which comprises in its interior a space for receiving a powdered medicament and stabilises this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilising function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.Type: ApplicationFiled: April 13, 2007Publication date: October 8, 2009Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Hubert Kunze, Achim Moser, Elmar Mock, Antonino Lanci, Andre Kloppenstein
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Publication number: 20090181191Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: ApplicationFiled: February 4, 2009Publication date: July 16, 2009Applicant: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
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Publication number: 20090101145Abstract: The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.Type: ApplicationFiled: April 13, 2007Publication date: April 23, 2009Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Herbert Wachtel, Johannes Geser, Burkhard Metzger, Michael Spallek, Michael Krueger, Herbert Kunze, Achim Moser, Elmar Mock, Antonio Lanci, Andre Klopfenstein
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Publication number: 20080295578Abstract: In a method for checking the permeability rate of a closed container (3) with respect to a medium, in particular for checking the permeability rate of a film-type container for accommodating a film container for accommodating a pharmaceutical active constituent formulation, the container (3) is filled with a medium, charged with a gas, and the increase in the amount of medium in the gas is then analysed.Type: ApplicationFiled: July 24, 2006Publication date: December 4, 2008Inventors: Daniela Bothe, Hubert Hoelz, Christoph Kreher, Burkhard Metzger, Christian Scheffler