Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.

Abstract: Provided is a Michael addition product prepared from a multifunctional acryl monomer having multiple hydroxyl groups allowing introduction of acryl functional groups, as a Michael acceptor, and a Michael donor. The Michael addition product is a novel multifunctional compound having an oligomer and a photoinitiator moiety in the molecule. Since it can be cured under a standard UV curing condition without having to add a photoinitiator, it is reduced to air pollution or health problem. Therefore the superior physical properties were obtained by cured coatings without surface tackiness. In addition, its hydroxyl groups allow, through isocyanate bonding or introduction of acryl groups, 3-dimensional crosslinking and molecular and compositional design for improving expandability, friction, and reactivity and hydrophilicity for self-adhesion, hardness of cured film, or the like. Consequently, a very useful, multifunctional or water-dispersible coating composition may be prepared.

Abstract: Disclosed herein is a ring shaped rubber magnet for a spindle motor formed by coupling one surface and the other surface of a sheet shaped rubber magnet to each other, wherein one surface of the sheet shaped rubber magnet has an obtuse angle of 90 degrees or more at an edge of one end portion thereof and an acute angle of 90 degrees or less at an edge of the other end portion thereof, and the other surface of the sheet shaped rubber magnet has an acute angle of 90 degrees or less at an edge of one end portion thereof and an obtuse angle of 90 degrees or more at an edge of the other end portion thereof.

Abstract: The present invention is related to a composition comprising a serine as an active ingredient for treating or preventing fatty liver diseases. The inventive compound significantly inhibits the SREBP-1 transcription activity involved in lipid synthesis and reduced the fatty liver formation through various in vitro test and in vivo test therefore it can be useful in the prevention and treatment of the fatty liver diseases as a medicament or health functional food.

Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp 14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.

Abstract: The present invention relates to a blood manometer displaying the examined person's heart condition, showing the name of a cardiac disease identified, comprising a cuff pressure control portion for adjusting the air pressure of a cuff; a blood pressure measuring portion having a pressure sensor for measuring blood pressure; a pulse measuring portion having a pulse wave sensor for measuring pulse waves; and a central process-and-control portion which processes by computing the data inputted by the blood pressure measuring portion and the pulse measuring portion, and displays in words the results of the blood pressure that has been measured, such as normal blood pressure, hypertension or hypotension, as well as the result of the pulse that has been measured, such as normal pulse, arrhythmia, tachycardia or bradycardia. The central process-and-control portion is also capable of storing and transmitting the data.

Abstract: Disclosed herein is a mobile phone with a stethoscopic function. The mobile phone with a stethoscopic function, of which the mobile phone has communication data processing functions, comprises a stethoscopic microphone which is arranged in a body of the mobile phone; and a stethoscopic system which is embedded in the body of the mobile phone. The auscultated sound data obtained from the medical examination made on the part of a human body where the stethoscopic microphone is contacted are converted into digital auscultated sound data. The digital auscultated sound data identifies corresponding sound data in the pre-stored standardized digital auscultating sound data through search and comparison within allowable errors of data. With the identified data, a diagnostic data is made available. The diagnostic data may be stored and transmitted to a physician using the communication function of the mobile phone.

Abstract: There is provided a motor having an improved coupling structure between a circuit board and a base plate, and an optical disc drive using the same. The motor includes: a base plate; and a circuit board coupled to a surface of the base plate and having insulating layers formed on both surfaces thereof, wherein the insulating layers formed on both surfaces of the circuit board have different thicknesses. In particular, an insulating layer formed on one surface of the circuit board attached to the base plate may be thicker than an insulating layer formed on the other surface thereof.

Abstract: Provided is a Michael addition product prepared from a multifunctional acryl monomer having multiple hydroxyl groups allowing introduction of acryl functional groups, as a Michael acceptor, and a Michael donor. The Michael addition product is a novel multifunctional compound having an oligomer and a photoinitiator moiety in the molecule. Since it can be cured under a standard UV curing condition without having to add a photoinitiator, it is reduced to air pollution or health problem. Therefore the superior physical properties were obtained by cured coatings without surface tackiness. In addition, its hydroxyl groups allow, through isocyanate bonding or introduction of acryl groups, 3-dimensional crosslinking and molecular and compositional design for improving expandability, friction, and reactivity and hydrophilicity for self-adhesion, hardness of cured film, or the like. Consequently, a very useful, multifunctional or water-dispersible coating composition may be prepared.

Abstract: Disclosed is a motor including a rotor body mounted on a shaft and a chucking mechanism body mounted on a rotor hub, which are coupled with an increased coupling force by changing a coupling structure of the rotor hub of the rotor body and the chucking mechanism body mounted on the rotor hub. The motor includes: a sleeve rotatably supporting a shaft; a rotor body having a rotor hub mounted on the shaft; and a chucking mechanism body having a boss with a through hole in which the rotor hub is insertedly coupled and a space part formed within the boss and providing an elastic force when the rotor hub is coupled.

Abstract: The present invention provides a spindle motor assembly with an encoder. The spindle motor includes a circuit board, a spindle motor and an encoder. A connector is mounted on the upper surface of the circuit board. The spindle motor is provided on the circuit board. The spindle motor functions to rotate a disk placed thereon. The encoder is provided on the connector and senses a detection mark of the disk and thereby detects a rotating speed of the disk. As such, because the encoder is installed on the connector, the number of components is reduced, and the production cost can be thus reduced.

Abstract: Disclosed herein is a mobile phone with a stethoscopic function. The mobile phone with a stethoscopic function, of which the mobile phone has communication data processing functions, comprises a stethoscopic microphone which is arranged in a body of the mobile phone; and a stethoscopic system which is embedded in the body of the mobile phone. The auscultated sound data obtained from the medical examination made on the part of a human body where the stethoscopic microphone is contacted are converted into digital auscultated sound data. The digital auscultated sound data identifies corresponding sound data in the pre-stored standardized digital auscultating sound data through search and comparison within allowable errors of data. With the identified data, a diagnostic data is made available. The diagnostic data may be stored and transmitted to a physician using the communication function of the mobile phone.

Abstract: An automatic diagnostic apparatus with a stethoscope is disclosed in which the name of a disease is automatically determined and recorded based on auscultated sounds. Standard data of auscultated sounds for cardiovascular diseases, respiratory diseases and gastrointestinal diseases are inputted into a computer beforehand. Then the waveforms of the auscultated sounds from stethoscoping a patient are converted into digital data and inputted into a computer, and the digital data signals are compared, with searches, with the standard data which have been inputted into the computer in advance. By this process the names of diseases are determined, and the names of diseases thus determined are automatically recorded in a recording device and displayed on monitors so that treatment can initiate swiftly with enhanced credibility of the objective diagnostic process through consensus between the physician and the patient.

Abstract: A single health room is disclosed. A single room 1 has sound-proof walls 1a, a door 2 and a window 3. At a side of the rear wall, there are an oxygen supplier, an audio set 5 and an air conditioner 4 for automatically controlling temperature and humidity and for purifying the air. A bed 6 is installed within the single room 1, and a small table 7 is disposed beside the bed 6. A telephone 8 and a table light 9 are mounted on the small table 7. On the ceiling of the single room 1, there are installed a TV set 10, illuminating bulbs 11 and a cooling fan 12, the TV set 10 being watchable at a lying posture. The small table 7 has a plurality of switches 7s so as to make it possible to arbitrarily and selectively turn on the above apparatuses and devices. Therefore, the occupying person of the single health room can enjoy the quiet pleasant atmosphere of the room, and therefore, the stress of the person can be quickly relieved.

Abstract: An automatic diagnostic apparatus with a stethoscope is disclosed in which the name of a disease is automatically determined and recorded based on auscultated sounds. Standard data of auscultated sounds for cardiovascular diseases, respiratory diseases and gastrointestinal diseases are inputted into a computer beforehand. Then the waveforms of the auscultated sounds from stethoscoping a patient are converted into digital data and inputted into a computer, and the digital data signals are compared, with searches, with the standard data which have been inputted into the computer in advance. By this process the names of diseases are determined, and the names of diseases thus determined are automatically recorded in a recording device and displayed on monitors so that treatment can initiate swiftly with enhanced credibility of the objective diagnostic process through consensus between the physician and the patient.

Abstract: A health watch is disclosed which has various functions such as atmospheric air thermometer, body thermometer, cardiac beat meter, displaying of beating sound waves, display of cardiac beating sounds, blood pressure meter and the like. An IC counting element is provided for each of the functions, and a plurality of display windows are provided to display the respective measured data. For this purpose, sensors are installed on the watch in contact with the wrist. Thus the various functions are combined in one wrist watch, so that a convenience would be ensured by eliminating the troubles of carrying and storing the various conventional separate health checking devices. Therefore, one's own health state can be checked at any place, thereby making it possible to prevent assault of any disease.

Abstract: A piezo ceramic transformer working at a full wave length mode, &lgr;-mode, in accordance with the present invention has a driving region divided into two sections in the center and two generating regions at the end regions of a thin rectangular bar. Two input sections are built into multi-layered structure with multiple internal-electrodes and poled along the thickness direction with polarization in the neighboring layers opposite to each other. Alternating internal electrodes are connected in parallel through two external electrodes in each input section. Polarization in the same layer of two input sections are disposed in the same direction, and two external electrodes of two input sections in the same side of driving region are connected 180 degree out of phase to each other to a driving circuit. Two CCFLs are connected directly to two output electrodes at the end of the piezo ceramic transformer, respectively.

Abstract: A portable viewable and audible stethoscope for visually and audibly monitoring the vital life signs (e.g. heart beat, lung respiration, artery pulse, intestinal sounds) of a patient. The stethoscope includes a large diameter sound absorbing cup and a small diameter sound absorbing connected to opposite ends of a tubular connector and an output device enclosed within a hand held case that is connected to a middle region of the tubular connector by a supporting tube. The tubular connector is provided with an internally installed microphone which converts the absorbed sounds to electrical signals. The output device includes an electronic circuit assembly for amplifying the signals from the microphone, an oscilloscope for displaying the signals, and a speaker for converting the signals into audible sounds. The outside of the case of the output device is provided with control switches for the oscilloscope display, speaker volume adjustment and power on/off.