Abstract: Aspects of this disclosure concern controllers and control methods for applying a drive voltage to bus bars of optically switchable devices such as electrochromic devices. Such devices are often provided on windows such as architectural glass. In certain embodiments, the applied drive voltage is controlled in a manner that efficiently drives an optical transition over the entire surface of the electrochromic device. The drive voltage is controlled to account for differences in effective voltage experienced in regions between the bus bars and regions proximate the bus bars. Regions near the bus bars experience the highest effective voltage.

Abstract: Disclosed herein are low density particles comprising polymerized fibrin that are micrometer or nanometer sized in diameter. The particles can further include at least one therapeutic agent. The particles may be used to treat wounds, by administration directly or systemically to the site of the wound. Exemplary wounds that may be treated with the fibrin particles include a trauma wound, a surgical wound, a burn wound, or an ulcer wound. Also disclosed herein are methods for preparing the particles using a shearing process.

Abstract: Onboard EC window controllers are described. The controllers are configured in close proximity to the EC window, for example, within the IGU. The controller may be part of a window assembly, which includes an IGU having one or more EC panes, and thus does not have to be matched with the EC window, and installed, in the field. The window controllers described herein have a number of advantages because they are matched to the IGU containing one or more EC devices and their proximity to the EC panes of the window overcomes a number of problems associated with conventional controller configurations. Also described are self-meshing networks for electrochromic windows.

Abstract: Onboard EC window controllers are described. The controllers are configured in close proximity to the EC window, for example, within the IGU. The controller may be part of a window assembly, which includes an IGU having one or more EC panes, and thus does not have to be matched with the EC window, and installed, in the field. The window controllers described herein have a number of advantages because they are matched to the IGU containing one or more EC devices and their proximity to the EC panes of the window overcomes a number of problems associated with conventional controller configurations. Also described are self-meshing networks for electrochromic windows.

Abstract: Various embodiments herein relate to networks of electrochromic windows. The networks may be configured in particular ways to minimize the likelihood that the windows on the network draw more power than can be provided. The network may include particular hardware components that provide additional power to windows as needed. The network may also be configured to adjust how the windows therein transition to prevent overloading the network. The techniques described herein can be used to design networks of electrochromic windows that are undersized when considering the amount of power that would be needed to simultaneously transition all the windows on the network using normal transition parameters, while still allowing simultaneous transitions to occur.

Abstract: Disclosed herein are recombinant viral vectors comprising a liver specific promotor in operable combination with a heterologous nucleic acid sequence encoding a protein, such as a clotting factor. Methods of treating a subject with a clotting disorder, such as hemophilia A or hemophilia B, are also provided.

Abstract: A multiple pass, parallel flow downcomer tray for a mass transfer column and method for liquid-vapor contacting in a mass transfer column is provided. The multiple pass, parallel flow downcomer tray has at least four mass transfer decks configured to provide contact between an ascending vapor passing upward through apertures on the tray surface and a traversing liquid on the tray surface. The tray further includes a central downcomers disposed near a central axis of the tray and two or more peripheral downcomers disposed near the edge of the tray and spaced apart from the central axis, wherein at least two of the four mass transfer decks are configured to discharge the traversing liquid into the peripheral downcomers and two of the four mass transfer decks are configured to discharge the traversing liquid into the central downcomer.

Abstract: Certain aspects pertain to a combination sensor comprising a set of physical sensors facing different directions proximate a structure, and configured to measure solar radiation in different directions. The combination sensor also comprises a virtual facade-aligned sensor configured to determine a combi-sensor value at a facade of the structure based on solar radiation readings from the set of physical sensors.

Abstract: The present disclosure relates to a protective enclosure to secure occupants against external threats, such as ballistic projectiles, blasts, or natural phenomena.

Abstract: A method and system for managing payment transactions for a merchant using a computing device coupled to a memory device is described. Each transaction is initiated by a consumer using a payment card. The method includes receiving a registration request from a candidate merchant for enrollment within a manager module wherein the registration request includes registration data associated with the candidate merchant, executing a primary approval process using at least some of the registration data, and transmitting an account request message requesting an opening of a merchant account for the candidate merchant with an acquiring bank upon approval. The method further includes receiving, in real-time, merchant account data associated with the candidate merchant from the acquiring bank upon approval by a secondary approval process wherein the candidate merchant becomes a registered merchant upon the secondary approval.

Abstract: A modular approach is provided for sensing and responding to detected activity or an event in a region that can be implemented quickly and easily using existing city infrastructure to establish a grid of sensors and detectors to provide localized or wide area coverage. The approach provides a turnkey solution or smart city in a box that can be adapted to different situations and needs to provide communications functionality and/or a desired or customized functionality for a wide range of different applications.

Abstract: Methods and apparatuses (including systems and devices), including computer-implemented methods for segmenting, correcting and/or modifying a three-dimensional (3D) model of a subject's oral cavity to determine individual components such as teeth, gingiva, tongue, palate, etc., that may be selective and/or collectively digitally manipulated. In some implementations, artificial intelligence uses libraries of labeled 2D images and 3D dental models to learn how to segment a 3D dental model of a subject's oral cavity using 2D images, height map and/or other data and projection values that relate the 2D images to the 3D model. As noted herein, the dental classes can include a variety of intra-oral and extra-oral objects and can be represented as binary values, discrete values, a continuum of height map data, etc. In some implementations, several dental classes are predicted concurrently.

Abstract: Methods and apparatuses (including systems and devices) for modifying a three-dimensional (3D) model of a subject's oral cavity to determine individual components such as teeth, gingiva, tongue, palate, etc. In some implementations one or more automated machine learning agents may modify one or more subsets of 3D models of the subject's oral cavity using height map data to identify, segment and/or modify to mesh regions of a 3D model constructed from a plurality of 2D images of the subject's dental cavity.

Abstract: Various embodiments herein relate to networks of electrochromic windows. The networks may be configured in particular ways to minimize the likelihood that the windows on the network draw more power than can be provided. The network may include particular hardware components that provide additional power to windows as needed. The network may also be configured to adjust how the windows therein transition to prevent overloading the network. The techniques described herein can be used to design networks of electrochromic windows that are undersized when considering the amount of power that would be needed to simultaneously transition all the windows on the network using normal transition parameters, while still allowing simultaneous transitions to occur.

Abstract: At least one elongated photobioreactor, at a small angle relative to horizontal and mixed substantially or entirely by large bubble flow, is used for contained cell culture, e.g., microalgae cultivation. Elongated, flexible, transparent, polymeric photobioreactor tubes, in near-grade and near-horizontal (e.g. sloped 1 degree to 3 degrees) orientation, and use of low-pressure air mixing, allow very inexpensive construction and operation. Multiple elongated tubes may be used for an independent operation of the multiple photobioreactor tubes for the same or different cells, e.g., microalgae and different applications. Low-pressure air is delivered near the low end of the bioreactor at less than 10 psig and without sparging, to produce large air bubbles that travel from the low end to the high end of the bioreactor, for turbulent mixing and gas exchange.

Abstract: An annular divided wall column for the cryogenic rectification of air or constituents of air is provided. The annular divided wall column includes a first annular column wall and a second annular column wall disposed within the first annular column wall to define an annulus column region and an interior core column region. The present annular divided wall column further includes structured packing elements disposed within at least the annulus column region as well as a ring-shaped cantilevered collector; and a ring-shaped distributor disposed in the annulus column region above or below the plurality of structured packing elements. The thermal expansion and contraction of the second annular column wall in a radial direction and in an axial direction is independent of the thermal expansion and contraction of the first annular column wall in the radial and axial directions.

Abstract: A minimal antigen delivery system consists essentially of PEGylated stealth liposomes loaded with an immunogenic human leukocyte antigen (HLA) class restricted peptide and surface modified with a cell targeting peptide which mediates binding and internalization of the liposomes into a target cell.

Abstract: “Smart” controllers for windows having controllable optical transitions are described. Controllers with multiple features can sense and adapt to local environmental conditions. Controllers described herein can be integrated with a building management system (BMS) to greatly enhance the BMS's effectiveness at managing local environments in a building. The controllers may have one, two, three or more functions such as powering a smart window, determining the percent transmittance, size, and/or temperature of a smart window, providing wireless communication between the controller and a separate communication node, etc.

Abstract: This disclosure describes insulated glass units (IGUs) that incorporate electrochromic devices. More specifically, this disclosure focuses on different configurations available for providing an electrical connection to the interior region of an IGU. In many cases, an IGU includes two panes separated by a spacer. The spacer defines an interior region of the IGU and an exterior region of the IGU. Often, the electrochromic device positioned on the pane does not extend past the spacer, and some electrical connection must be provided to supply power from the exterior of the IGU to the electrochromic device on the interior of the IGU. In some embodiments, the spacer includes one or more holes (e.g, channels, mouse holes, other holes, etc.) through which an electrical connection (e.g., wires, busbar leads, etc.) may pass to provide power to the electrochromic device.

Abstract: Disclosed herein are recombinant viral vectors comprising a liver specific promotor in operable combination with a heterologous nucleic acid sequence encoding a protein, such as a clotting factor. Methods of treating a subject with a clotting disorder, such as hemophilia A or hemophilia B, are also provided.