Abstract: Methods for treating pruritis in humans and animals using topically administrable compositions containing olopatadine are disclosed. The compositions quickly relieve itchy skin.

Abstract: Systems and methods are provided for train operation control and enforcement. A train control system for controlling operations of a train may include a train-mounted control unit deployed in the train, and a plurality of fixed control nodes deployed on or in close proximity to a track traversed by the train. Each of the train-mounted control unit and fixed control nodes includes a corresponding communication subsystem that includes transponders and communication circuits, configured for communicating signals. The train-mounted control unit is configured to transmit signals to and receive signals from the plurality of fixed control nodes, with the signals including ultra-wideband (UWB) signals and with at least some of the signals carrying data pertinent to controlling operations of the train; and to determine control information relating to controlling operations of the train based on received UWB signals originating from one or more fixed control nodes.

Abstract: Methods and systems for depth-based foveated rendering in a display system are disclosed. The display system may be an augmented reality display system configured to provide virtual content on a plurality of depth planes using different wavefront divergence. Some embodiments include monitoring eye orientations of a user of the display system. A fixation point can be determined based on the eye orientations, the fixation point representing a three-dimensional location with respect to a field of view. Location information of virtual object(s) to present is obtained, with the location information including three-dimensional position(s) of the virtual object(s). A resolution of the virtual object(s) can be adjusted based on a proximity of the location(s) of the virtual object(s) to the fixation point. The virtual object(s) are presented by the display system according to the adjusted resolution(s).

Abstract: A vehicle storage system includes a base that is configured to be disposed on seating assemblies within a rear seating space. A first partition is coupled to the base, and the first partition extends along a first edge of the base. A second partition is spaced from the first partition. The second partition is coupled to the base and extends along a second opposing edge of the base. A cross member is coupled to a top edge of each of the first partition and the second partition. The cross member extends adjacent to a headliner.

Abstract: Systems and methods are provided for worker protection system with ultra-wideband (UWB) based anchors. A plurality of wayside units may be configured for placement on or near a track, with each wayside unit comprising one or more circuits. The wayside units may be configured to transmit and/or receive wireless signals, comprising ultra-wideband (UWB) signals. The plurality of wayside units may automatically form a work zone network comprising one or more activated wayside units from the plurality of wayside units. The one or more activated wayside units may be activated in response to at least one activation condition to a work zone in an area surrounding or in proximity to the plurality of wayside units. When the work zone network is formed, provide in the work zone network, based on communication of UWB signals, worker protection related functions within an area surrounding or in proximity to the plurality of wayside units.

Abstract: A lubrication system is provided for lubricating a plurality of picker units connected to an agricultural machine. Each of the plurality of picker units includes a cam track assembly, an idler gear assembly, a drum and drive gear assembly, and a drum assembly. The lubrication system includes a supply of lubricant and a pump fluidly coupled to the supply. A primary distributor is fluidly coupled to the pump and includes a plurality of outlets fluidly coupled to each of the plurality of picker units. A plurality of secondary distributors is each fluidly coupled to one of the plurality of outlets of the primary distributor. Each of the plurality of second distributors is fluidly coupled to one of the plurality of picker units. The primary distributor is configured to distribute an equal amount of lubricant in a given cycle to each of the plurality of secondary distributors.

Abstract: Methods and systems for depth-based foveated rendering in the display system are disclosed. The display system may be an augmented reality display system configured to provide virtual content on a plurality of depth planes using different wavefront divergence. Some embodiments include monitoring eye orientations of a user of a display system based on detected sensor information. A fixation point is determined based on the eye orientations, the fixation point representing a three-dimensional location with respect to a field of view. Location information of virtual objects to present is obtained, with the location information indicating three-dimensional positions of the virtual objects. Resolutions of at least one virtual object is adjusted based on a proximity of the at least one virtual object to the fixation point. The virtual objects are presented to a user by display system with the at least one virtual object being rendered according to the adjusted resolution.

Abstract: A method for redirecting a user equipment (UE) from a first network to a second network is described. The method includes determining, at a wireless access point of the first network, information for the UE about one or more mobile network operator (MNO) networks. The method also includes selecting the second network for redirection from among the one or more MNO networks based on the determined information. The method further includes sending the UE a redirection message that redirects the UE from the first network to the second network.

Abstract: A vehicle storage system includes a base that is configured to be disposed on seating assemblies within a rear seating space. A first partition is coupled to the base, and the first partition extends along a first edge of the base. A second partition is spaced from the first partition. The second partition is coupled to the base and extends along a second opposing edge of the base. A cross member is coupled to a top edge of each of the first partition and the second partition. The cross member extends adjacent to a headliner.

Abstract: A method for redirecting a user equipment (UE) from a first network to a second network is described. The method includes determining, at a wireless access point of the first network, information for the UE about one or more mobile network operator (MNO) networks. The method also includes selecting the second network for redirection from among the one or more MNO networks based on the determined information. The method further includes sending the UE a redirection message that redirects the UE from the first network to the second network.

Abstract: Systems and methods are provided for worker protection system with ultra-wideband (UWB) based anchors. One or more wayside units placed on or near a track may be configured to form a work zone network, based on ultra-wideband (UWB) communications, corresponding to a work zone in an area surrounding or in proximity to the one or more wayside units. When the work zone network is formed, at least one wayside unit of the one or more wayside units may be configured to obtain ranging information to a train traversing the track, based on communications of UWB signals with at least one train-mounted unit deployed on the train, and the one or more wayside units are configured to generate, based on the ranging information, notifications relating to the train and/or the work zone.

Abstract: A head mounted display system can include a camera, at least one waveguide, at least one coupling optical element that is configured such that light is coupled into the waveguide(s) and guided therein, and at least one out-coupling element. The at least one out-coupling element can be configured to couple light that is guided within the waveguide(s) out of the waveguide(s) and direct the light to the camera. The at least one coupling element may include a diffractive optical element having optical power. Additionally or alternatively, the at least one coupling optical element may have a coupling area, for coupling light into the waveguide(s), the coupling area having an average thickness in a range from 0.1 to 3 millimeters across and/or may have a pinhole sized and/or slit shaped coupling area.

Abstract: A head-mounted display system is configured to project light to an eye of a user wearing the head-mounted display system to display content in a vision field of said user. The head-mounted display system comprises at least one diffusive optical element, at least one out-coupling optical element, at least one mask comprising at least one mask opening, at least one illumination in-coupling optical element configured to in-couple light from at least one illumination source into a light-guiding component, an image projector configured to in-couple an image and an at least one illumination source is configured to in-couple light into at least one illumination in-coupling optical element, an eyepiece, a curved light-guiding component, a light-guiding component comprising a portion of a frame, and/or two light-guiding components disposed on opposite sides of at least one out-coupling optical element.

Abstract: Systems and methods for generating a trajectory model characterizing a disease state and using the trajectory model in determining a recommended treatment. In one aspect, a method includes obtaining patient data, in which the patient data includes clinical laboratory results of a patient with a disease state; processing the patient data such that the clinical laboratory results are normalized by patient-specific or cohort-specific baseline levels of the clinical laboratory results; and applying a trajectory model to the processed patient data to identify a likelihood of an adverse outcome of the patient, in which the trajectory model characterizes the disease state by a recovery trajectory in a phase-plane of one or more variables.

Abstract: A head mounted display system can include a camera, at least one waveguide, at least one coupling optical element that is configured such that light is coupled into said waveguide and guided therein, and at least one out-coupling element. The at least one out-coupling element can be configured to couple light that is guided within said waveguide out of said waveguide and direct said light to said camera. The at least one coupling element may comprise a diffractive optical element having optical power. Additionally or alternatively, the at least one coupling optical element may have a coupling area for coupling light into said waveguide having an average thickness in a range from 0.1 to 3 millimeters across and/or may have a slit shaped coupling area.

Abstract: Provided are recombinant adeno-associated virus (rAAV) virions, methods of treating an ocular condition, pharmaceutical compositions, and other compositions and methods, in which the rAAV virion comprises a poly nucleotide encoding a neurotrophic factor, such as Nerve Growth Factor (NGF) or Glial Derived Neurotrophic Factor (GDNF). Methods of treatment may include administration to the lacrimal gland.

Abstract: Systems and methods are provided for decentralized train control. A decentralized train system may include a plurality of wayside control units, configured for placement on or near tracks in a railway network, and one or more train-mounted units, each of which being configured for use in a particular train. Each wayside control unit may obtain information corresponding to each train that passes within its communication range, and provide obtained train-related information to each train-mounted unit passing within its communication range. Each train-mounted unit may configured to receive train-related information from each wayside control unit that comes within its communication range, process the received train-related information, assess based on the processing of the train-related information conditions relating to operation of train within the railway network, and when at least one condition meets one or more particular criteria, perform or cause performing one or more responsive actions.

Abstract: Methods that increase bioavailability and/or efficacy of a therapeutic agent for treatment of an ocular surface disorder, cornea disorder, or anterior chamber disorder are provided. In particular, tear production is increased by administration of an electrical stimulus, ultrasound stimulus, and/or a drug such as an nAChR?7 agonist (e.g., varenicline, (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, 5-{(E)-2-[(3R)-pyrrolidin-3-yl]vinyl}pyrimidine, or (R,E)-5-(2-pyrrolidine-3-yl)vinyl)pyrimidine). The primary therapeutic agents provided include recombinant adeno-associated virus (AAV) vectors expressing a therapeutic gene product (e.g., a biologic drug). Related compositions methods of use are also provided.

Abstract: Examples of wearable systems and methods can use multiple inputs (e.g., gesture, head pose, eye gaze, voice, and/or environmental factors (e.g., location)) to determine a command that should be executed and objects in the three-dimensional (3D) environment that should be operated on. The multiple inputs can also be used by the wearable system to permit a user to interact with text, such as, e.g., composing, selecting, or editing text.