Abstract: An apparatus for conveying a web using an engagement cover comprising resilient looped pile engagement surface.

Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

Abstract: A method of fabricating a nozzle that includes casting and curing a first material using a patterned nip roller to form a first microstructured pattern of discrete microstructures, deforming at least one of the discrete microstructures; replicating the first microstructured pattern, including the at least one deformed discrete microstructure, in a second material different than the first material to make a replicated structure comprising a plurality of blind holes formed in the second material, removing second material of the replicated structure to expose tops of microstructures in the first microstructured pattern, and removing the first material from the replicated structure, resulting in a nozzle having a plurality of through-holes in the second material and corresponding to the first microstructured pattern.

Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.

Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

Abstract: There is provided a thermoformable article comprising at least a first surface having a binder resin layer comprising a fluorine-containing polymer, where the binder resin layer has a first major surface opposite a second major surface; and a plurality of microspheres partially and adhered to the first major surface of the binder resin layer; where the fluorine-containing polymer is a partially fluorinated polymer derived from at least one fluorine containing monomer and two or more non-fluorinated monomers having at least one active hydrogen functional group, and further wherein at least one but not all of the active hydrogen functional groups are reacted with at least one curing agent having latent functionality. In some instances the curing agent comprises polyisocyanate. There is also provided a thermoset article derived from such thermoformable articles.

Abstract: There is provided an article a binder resin layer comprising an aliphatic polyurethane polymer comprising a plurality of soft segments, and a plurality of hard segments, where the soft segments comprise poly(alkoxy) polyol, and where the poly(alkoxy) polyol is essentially free of crosslinker; and a plurality of microspheres partially embedded and adhered to a first major surface of the binder resin layer, wherein the specific chemical identities and relative amounts of the segments and moieties of the aliphatic polyurethane polymer are sufficient to impart a glass transition temperature of 10° C. or less in the article and a storage modulus in the article that changes less than 15 MPa from 25° C. to 175° C.

Abstract: Systems and methods are described for control and/or asset performance management of a system, in-situ, at an asset. A system application model can be deployed to at least a first network node fixed, in-situ, at the asset using a short-range, low-power communication network. The first network node can execute a master avatar using the deployed system application model and generate, at a second network node, a master-slave avatar using the master avatar executed at the first network node. The master avatar and/or master-slave avatar can be configured to perform control of the system, in-situ, at the first network node and the second network node.

Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

Abstract: Disclosed herein is a floor contact sensor system having a data acquisition terminal and a sensor sheet assembly having at least one sensor sheet. Each sensor sheet has a base sheet and selected spaced conductive portions extending upwardly therefrom that are in communication with the data acquisition terminal. The conductive portions are a composite material formed of a polymer and a conductive filler such that the conductive portions can have physical characteristics essentially identical to the polymer, while being electrically conductive with the electrical resistance proportional to the load on the sensor. The floor contact sensor system can be configured to provide real time dynamic contact information for overlying flooring materials during use.

Abstract: A system and method of executing secure communications between first and second domains includes a first logical unit and a second logical unit. The first logical unit periodically calculates timestamps and hashes. The first logical unit also transmits a web form to a node of a first domain responsive to a request and the web form is displayed to a user. The first logical unit receives data input to said web form by the user and enhances the data by adding one or more security services. The first logical unit translates the received data from a first network application level protocol to a target network application level protocol while preserving said data security enhancements and transmits the translated data across a public network. A second logical unit de-enhances the translated data and filters the translated data data. The second logical unit further authorizes the filtered data and transmits the filtered data to a node of the second domain for use in an application.

Abstract: Described herein is decorative article having a coefficient of friction less than 0.3 wherein the decorative articles comprises: (i) a microsphere layer comprising a plurality of microspheres, wherein the microsphere layer comprises a monolayer of microspheres and wherein the plurality of microspheres are in a microscopic periodic pattern; and (ii) a bead bonding layer disposed on the microsphere layer, wherein the plurality of microspheres are partially embedded in the bead bonding layer. Also disclosed herein are transfer articles and methods of making the decorative articles and transfer articles.

Abstract: Systems and methods of a Hierarchical Smart Asset Control Application development and Integrated Smart Asset Control System optimization are disclosed. In various embodiments, the system may develop a Hierarchical Asset Control Application and corresponding control hardware requirements. This can be used to create an Integrated Smart Asset Control System in order execute various processes for a set of equipment elements. The smart assets associated with the system may utilize intelligent agents to balance operational constraints and operational objects in order to determine real-time optimized operational parameters for a process and implement the appropriate controls to facilitate achieving the improved operational objectives.

Abstract: Techniques are provided for executing a software product that includes a plurality of machine instructions and that is associated with a measured usage pricing model. The executing of the software product includes tracking the usage of one or more computing resources for executing the software product in accordance with the associated measured pricing model. The executing also includes, for each of multiple sets of machine instructions, determining whether the set is associated with a token indicating that the set is a set of diagnostic machine instructions related to the executing of the software product. For each of those multiple sets of machine instructions, the executing of the software product further includes, responsive to a determination that the set of machine instructions is associated with the token, not tracking the usage of the one or more computing resources during execution of that set of diagnostic machine instructions.

Abstract: Systems and methods of a Hierarchical Smart Asset Control Application development and Integrated Smart Asset Control System optimization are disclosed. In various embodiments, the system may develop a Hierarchical Asset Control Application and corresponding control hardware requirements. This can be used to create an Integrated Smart Asset Control System in order execute various processes for a set of equipment elements. The smart assets associated with the system may utilize intelligent agents to balance operational constraints and operational objects in order to determine real-time optimized operational parameters for a process and implement the appropriate controls to facilitate achieving the improved operational objectives.

Abstract: A confectionery product comprises a first side and a second side generally opposite to the first side; the second side comprising an abrasive surface that is suitable for scrubbing the top surface of a tongue within the oral cavity. In preferred embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) by including abrasive inclusions in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive inclusions. The confectionery product is preferably a hard confectionery, but may also be a chewing gum product. A preferred confectionery product comprises a second side with a width and a length, the smallest of which is at least 1.6 times the product thickness.

Abstract: Techniques are provided for executing a software product that includes a plurality of machine instructions and that is associated with a measured usage pricing model. The executing of the software product includes tracking the usage of one or more computing resources for executing the software product in accordance with the associated measured pricing model. The executing also includes, for each of multiple sets of machine instructions, determining whether the set is associated with a token indicating that the set is a set of diagnostic machine instructions related to the executing of the software product. For each of those multiple sets of machine instructions, the executing of the software product further includes, responsive to a determination that the set of machine instructions is associated with the token, not tracking the usage of the one or more computing resources during execution of that set of diagnostic machine instructions.

Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.