Abstract: The present invention provides various processes for the preparation of (R)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.

Abstract: Improved methods for purification, detection or characterization of molecules have been described in embodiments of the present invention. The improved methods rely on the ability to create a carrier reagent which is capable of (i) binding to a matrix either specifically or non-specifically; and (ii) forming a covalent linkage with any ligand having a nucleophilic group or a thioester as a result of a simple reaction which does not require a variety of chemical reagents or sophisticated chemistry. The covalent linkage between the carrier and the ligand relies on the chemical reaction between a thioester and a nucleophilic group. The carrier should either contain a reactive thioester which if it is a protein should be at the C-terminal end of the protein or a reactive nucleophilic group which if it is a protein should be at the N-terminal end and should preferably be a cysteine or selenocysteine.

Abstract: A multi-tier rotary grill for grilling and heating food items such as hot dogs, sausages, metts and similar food items. The rotary grill includes heated rollers that are arranged in vertically spaced apart roller tiers. The rollers in the multiple roller tiers lie in common respective planes that are substantially parallel to each other and may slope upwardly from a front to a back of the rotary grill.

Abstract: A medical bandaging product having a predetermined length suitable for a given medical use, including an enclosure formed of a moisture-impervious material sealable to prevent entry of moisture and a medical bandage material positioned therein and sealed against entry of moisture until use. The medical bandage material includes a substrate formed from a single integrated knitted fabric layer having a plurality of interconnected knitted fabric yarns forming a three-dimensional structure. A reactive system is impregnated into or coated onto the substrate. The system remains stable when maintained in substantially moisture-free conditions and hardens upon exposure to sufficient moisture to cooperate with the three-dimensional structure to form a rigid, self supporting structure. A soft, flexible protective wrapping encloses the substrate along its length for providing a cushioning barrier interposed between the substrate and a patient when the medical bandage material is in use.

Abstract: Methods and compositions are provided which relate to translocating an RNA corresponding to a gene or gene fragment into the chloroplast by means of a chloroplast localization sequence. Additionally plant cells are described in which the chloroplast contains a ribozyme fused at one end to an RNA encoding a fragment of the protein such that the ribozyme can trans-splice the translocated fusion RNA to the RNA encoding the gene fragment to form an intact mRNA encoding a functional protein.

Abstract: The present invention is a method for preparing micron-sized or submicron-sized drug particles comprising contacting a solution comprising a poorly water soluble drug substance and at least one freezable organic solvent with a cold surface so as to freeze the solution; and removing the organic solvent. The resulting particles are also disclosed, as are several embodiments of an apparatus that can be used in performing the method of the present invention.

Abstract: A thick middleware adapter is presented that handles data related services within the adapter itself using generally reusable components connected in series. On the sending side of a communication, these components first convert the data from the native format of the application into raw XML. Next, the raw XML is transformed into the canonical XML defined by the enterprise using an XSLT stylesheet. The data is then validated and compressed, and then combined with a middleware message header. Another component in the adapter is the responsible for chunking, grouping, and encryption of the message, while a last component submits the completed message to the middleware transport layer. The components in a receiving adapter perform the opposite functions to convert the message received from the middleware transport layer into a message that is understood by the receiving application.

Abstract: A new type of transgene system is disclosed which allows efficient protein expression in a target host such as a plant, but avoids the undesirable result of the migration of the transgene into related host systems and/or to the environment via the pollen. The methods described herein may also be applied to the expression of virtually any protein of interest (e.g. a toxic protein) in eukaryotic (yeast, insect, mammalian cells, etc.) and prokaryotic (E. coli, etc.) organisms.

Abstract: A quick-mount support includes a fixed retainer adapted to extend into a first retainer aperture and a movable retainer having an arcuate slot and adapted to extend into a second retainer aperture. The quick-mount support further includes a pivotable actuator, apparatus for mounting the pivotable actuator for pivoting movement about an actuator pivot axis, and a driver coupled to the pivotable actuator and arranged to move in the arcuate slot in the movable retainer. Movable retainer pivots about the retainer pivot axis toward and away from the fixed retainer in response to pivoting movement of the pivotable actuator about the actuator pivot axis. In one illustrative embodiment, the mounting apparatus comprises an elastic, deformable O-ring for pivotally mounting the pivotable actuator about an anchor mount so that the actuator pivot axis can shift as the driver moves in the arcuate slot.

Abstract: A telescoping slide assembly support system includes a stationary slide and a slide support coupled to the stationary slide and to a rack included in an equipment cabinet.

Abstract: In a system for providing media content to a communication device, a device capabilities determination is made by a rules engine that compares content attributes with constraints on those attributes for a device. Metadata describing the content is derived and entered into a database. As the specifications of different devices are entered into the system, corresponding constraints are associated with the devices that tell the engine the valid range of values for the content attributes. The engine creates an available content library for each class of devices by excluding all instances of content that have attributes outside the range of values prescribed in the constraints. A similar rule set determines whether the content can be distributed through a particular delivery channel, based on the distribution channel capacity to support a media type.

Abstract: The present invention provides various processes for the preparation of (R)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.

Abstract: A hinge mounting assembly for an associated door panel is used for mounting to a panel to a storage rack. The rack generally includes at least one post having a front face and a side face. The front face has slots therein and the door panel generally has at least one bore defined therein. The hinge mounting assembly has a post plate and a door clamping member. The post plate has a hinge portion with a first end and a second end. The first end has bearing surfaces and an intermediate helical bearing surface. A door clamping member is pivotally mounted to the post plate. The door clamping member has a hinge post with a bearing surfaces and a helical bearing surface. The helical bearing surfaces enable the hinge mounting assembly to be “self closing” as well as reversibly mounted to the post.

Abstract: A computer-implemented method and mechanism represents system management information for components of a system as instances of managed object classes. A plurality of tables are provided with at least one table including instance entries for instances of physical object classes representing physical entities. Attribute entries for attributes of the physical object classes are mapped to instance entries in the tables. The allocation of attributes to attribute entries can be effected so as to mirror a class inheritance hierarchy. Also, attributes of logical object classes representing logical entities are mapped to the tables to represent associations between the physical object classes and the logical object classes.

Abstract: A cast tape or medical bandaging product formed from a resin-coated or impregnated fabric material that includes a knitted substrate having a combination of non-fiberglass high and low tenacity yarns such as polypropylene, polyester and elastomer. The polypropylene and polyester yarns have a high number of filaments, typically 48 to 90 filaments. This significantly improves the surface area of the fabric, that helps help to hold the curable resin onto the fabric and avoids pooling. This in turn improves lamination layer-to-layer and gives the substrate high strength.

Abstract: A combination carpenter square and bevel/sliding bevel having three triangle-shaped adjoining legs, with an articulating joint between the hypotenuse leg and each adjoining leg. The other two non-hypotenuse legs are capable of forming a substantially 90 degree angle between the two non-hypotenuse legs to function as a carpenter's square. At least one of the articulating joints at the hypotenuse leg is capable of tightening and loosening. The hypotenuse leg also consists of a slot positioned longitudinally of the hypotenuse leg. The tightening and loosening articulated joint joins the hypotenuse leg with an adjacent non-hypotenuse leg through the slot, which allows the adjacent non-hypotenuse leg movement about the joint relative to the hypotenuse leg to function as a bevel. The articulated joints allow the combination square and bevel/sliding bevel to be folded into a compact shape.

Abstract: A module is formed in which semiconductor components are soldered to an electrically conductive heat sink. The electrically conductive heat sink is formed so that it will serve as an electrical bus in an electronic device. The chips of the semiconductor component are metallurgically bonded to the surface of the heat sink. The heat sink uses a heat transfer fluid that flows through an interior of the heat sink, the interior containing an internal element. In the preferred embodiment, the internal element is a plurality of silver plated copper balls. The copper balls are brazed to each other and to the walls of the heat sinks in an assembly process. The heat sink housing will typically be made from copper, with one surface made from molybdenum so that the expansion and contraction of the heat sink housing molybdenum surface will be similar to that of the silicon substrate of the chips, thereby avoiding the problem of the chip substrate cracking and breaking due to thermal flexing.

Abstract: An automatic popcorn popper which has selectable load capabilities for popping various differently sized loads of corn. A heat control system is provided having a selector switch for selecting one of multiple rates of heat to be delivered to the kettle. An oil delivery system is coupled to the selector switch for selecting one of varying amounts of oil to be delivered to the kettle in conjunction with selecting the rate or amount of heat to be delivered to the kettle.

Abstract: A system for communicating with a residential electrical load center, including a residential electrical wiring system and at least one electronic communicating circuit breaker. The electronic communicating circuit breaker includes a fuse protected communications and control module. The system provides power to the fuse protected communications and control module utilizing the residential electrical wiring system, and operates the electronic communicating circuit breaker utilizing the fuse protected communications and control module regardless of whether the electronic communicating circuit breaker is in an ‘Open’ or ‘Closed’ state.