Abstract: The invention includes a system and method for managing an operation of a locomotive as a function of a location of the locomotive. The system comprises a location unit for determining the location of the locomotive and a control unit for controlling an operation of the locomotive as a function of the determined location. In another embodiment, the invention includes a system and method for receiving a security authorization input from an operator of the locomotive, comparing the received operator security authorization input to a security authorization parameter, and restricting an operation of the locomotive when the received operator security authorization input does not match the security authorization parameter. In yet another embodiment, the invention includes a system and method of sending a control command from a remote system, receiving the control command at the locomotive, and controlling an operation of the locomotive responsive to the received control command.

Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.

Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.

Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.

Abstract: Methods, computer program products and systems are provided for detecting large genomic rearrangements based on unphased genotype data obtained using common genotyping techniques that do not differentiate different alleles. In the method, unphased genotypes at a plurality of nucleotide variant markers of a particular gene in a diploid subject are compared with a canonical haplotype collection of the gene for a heterogeneous subject population. If the unphased genotypes cannot be reduced to a pair of canonical haplotypes within the canonical haplotype collection, it would indicate an increased likelihood that an allele of the gene in the diploid subject harbors a genomic rearrangement.

Abstract: Techniques are described for valuing, insuring, and certifying a valuation of landscape architectures. According to exemplary embodiments, a method for valuing landscape architectures includes identifying a landscape architectural object, and determining a future value associated with the landscape architectural object. The determined future value is based on at least one of a material cost associated with the landscape architectural object and an installation cost associated with an installing of the landscape architectural object in a landscape architectural setting. A growth rate is associated with the landscape architectural object, and a size of the object is determined using the growth rate. The material and installation costs can be determined based on at least one of the determined size, aggregate pricing information, and environmental and economic trends.

Abstract: Methods and a system are disclosed for insuring landscape architectural objects. According to an exemplary embodiment, a value associated with a landscape architectural object is determined. A change in the value of the object is determined over a period of time. A risk-of-loss to the object is determined attributable to an eligible event that can occur over the time period. A cost of an indemnity against a loss to the object is determined from the eligible event over the time period based on the change in value and the risk-of-loss.

Abstract: The invention includes a system and method for managing an operation of a locomotive as a function of a location of the locomotive. The system comprises a location unit for determining the location of the locomotive and a control unit for controlling an operation of the locomotive as a function of the determined location. In another embodiment, the invention includes a system and method for receiving a security authorization input from an operator of the locomotive, comparing the received operator security authorization input to a security authorization parameter, and restricting an operation of the locomotive when the received operator security authorization input does not match the security authorization parameter. In yet another embodiment, the invention includes a system and method of sending a control command from a remote system, receiving the control command at the locomotive, and controlling an operation of the locomotive responsive to the received control command.

Abstract: Large deletions have been identified in the BRCA1 gene in patients. The large deletions predispose the patients to breast cancer and ovarian cancer. Thus, methods for detecting the genetic variants are provided which can be used in detecting a predisposition to cancer.

Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.

Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.

Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.

Abstract: Compounds and methods for the diagnosis and treatment of tuberculosis are disclosed. Compounds include the M. tuberculosis antigens Mtb-81 and Mtb-67.2, immunogenic portions thereof and polynucleotides that encode such portions. Such compositions may be used, for example, for the immunotherapy and serodiagnosis of M. tuberculosis infection.

Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.

Abstract: In a wireless security system having a plurality of RF sensor/transmitters and a system controller, jamming signals are detected by comparing a near-term noise value with the expected signal strength of transmissions from the RF sensor/transmitters minus a detection threshold, and with the sum of a long-term noise value and a jamming threshold. In addition, the trend of the long-term noise value is analyzed to determine whether a jamming signal is being intentionally and gradually introduced into the security system environment. The system controller may include a plurality of antennas. Jamming may be detected for each antenna or for all of the antennas, collectively.

Abstract: An aqueous liquid detergent composition is provided for cleaning a hard surface and for repelling insects therefrom comprising a detersive proportion of a surface active detergent compound, an effective amount of an insect repellent material which is sufficient to repel insect from the hard surface after application of the detergent composition thereto, the liquid detergent composition being substantially free of a liquid hydrocarbon.

Abstract: An aqueous liquid detergent composition is provided for cleaning a hard surface and for repelling insects therefrom comprising a detersive proportion of a surface active detergent compound, an effective amount of at least one of certain defined insect repellent materials which is sufficient to repel insect from the hard surface after application of the detergent composition thereto, the liquid detergent composition being substantially free of a liquid hydrocarbon.

Abstract: A technique for providing volume adjustment capabilities in a digital telecommunication system. A composite two-part address is applied to a memory which stores amplitude adjusted digital voice words. The first part of the address comprises the digital voice word carried by the TDM time slot. The second part of the address comprises a parameter which defines the extent of amplitude adjustment. The readout of the memory thereby defines a different digital voice word having a desired amplitude level. The second address part of the composite address is generated by an amplitude parameter memory in synchronism with each time slot so that the amplitude of the digital voice words in corresponding time slots can be adjusted independently and dynamically with respect to the others.

Abstract: A communication system having full call processing capabilities in the user ports, each port being connected to a TDM collection bus and a TDM distribution bus. A bus controller terminates the collection bus on which voice words are deposited in time slots by the respective user ports, the voice words being realigned and transmitted by the bus controller on the TDM distribution bus. Each user port is assigned a time slot and can thus communicated simultaneously with one or more other user ports, such as during a two-way telephone conversation or a multiple party conference call. A memory in each user port combines plural voice words obtained from respective TDM time slots of conference participants, and combines such voice words into a composite signal representative of all the other conferees. The conference circuit of each user port combines the voice words of all the other participating ports over a frame period, except its own voice word, and thus the composite voice word of each user port is different.