Abstract: This document provides methods and materials for treating SYNGAP1-associated neurodevelopmental disorders (NDDs; e.g., SYNGAP1-related intellectual disability (SRID)). For example, viral vectors (e.g., adeno-associated viral (AAV) vectors) that include (e.g., are designed to include) nucleic acid encoding a truncated Syngap1 polypeptide (e.g., Syngap1-B:?1 polypeptide) are provided. In some cases, one or more viral vectors provided herein (e.g., AAV vectors that include nucleic acid encoding a truncated Syngap1 polypeptide such as a Syngap1-B:?1 polypeptide) can be administered to a mammal (e.g., a human) having, or at risk for developing, a SYNGAP1-associated NDD (e.g., SRID) to treat the mammal.

Abstract: A coated cathode material for lithium-ion batteries is disclosed. Methods and systems are further provided for applying a coating to an active cathode material for use in a lithium-ion battery. In one example, the coated cathode material may include a high-nickel content active cathode material, such as lithium nickel manganese cobalt oxide or lithium nickel aluminum cobalt oxide, coated with a coating including one or more high energy density active materials, such as lithium vanadium fluorophosphate and/or a lithium iron manganese phosphate compound. In some examples, the high-nickel content active cathode material may include greater than or equal to 60% nickel content.

Abstract: Beak opening apparatus and methods of using the same are described herein. The beak opening apparatus includes a beak splitter and beak opening actuator along with a control unit used to operate the beak opening actuator to move the beak splitter between a home position and an opening position to open the beak of a bird.

Abstract: System and methods related to wagering, such as slot machines and/or other electronic games. Some wagering may relate to market indicators, market lines, and/or stop commands.

Abstract: Implantable ports used for intravenous administration and methods of using the same.

Abstract: The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.

Abstract: In some embodiments, a method for encrypting a file includes receiving a file comprising file data and file metadata; retrieving a genomic differentiation object and genomic regulation instructions that define a set of operations that modify the genomic differentiation object; modifying the genomic differentiation object into a modified genomic differentiation object based on the genomic regulation instructions; extracting a sequence of bits from a predetermined set of bit locations of the file metadata; generating a genomic engagement factor based on the modified genomic differentiation object and the extracted sequence; and encrypting at least one portion of the file data using the genomic engagement factor.

Abstract: A system includes a content provider serving a first user webpage that displays an external posting link associated with a computer store and a second user webpage of a social networking service. The computer store contains posts each associated with a post select control. A computer server at the content provider is coupled to the computer store and for each of the posts is programmed to receive from a web browser of a computer user a signal indicating activation of the post select control of a selected one of the posts displayed by the first user webpage, automatically link the selected one of the posts to the external posting link, receive from the web browser of the computer user a signal indicating activation of the external posting link, and automatically issue the selected one of the posts to the second user webpage for posting thereon.

Abstract: A semiconductor structure including first shallow trench isolation regions and second shallow trench isolation regions, where the second shallow trench isolation regions are deeper than the first shallow trench isolation regions, and backside contact structures in direct contact with and physically separated by at least one of the second shallow trench isolation regions.

Abstract: The present technology relates to vascular access devices, systems, and methods configured to monitor a patient's health. In some embodiments, the vascular access device may include a sensing element, and the system of the present technology may be configured to obtain physiological measurements of the patient via the sensing element, determine at least one physiological parameter based on the physiological measurement, compare the at least one physiological parameter to a predetermined threshold, and, based on the comparison, provide an indication of the patient's health.

Abstract: A system and method and system for providing preoperative patient intraoral scanning for diagnosis and preparation of a treatment plan utilizing the proposed system in advance of the crown surgery and intraoperative patient intraoral scanning for system assessment and verification for the method of treatment. More specifically, the proposed invention proposes a method and system of patient intraoral scanning to identify the best predesigned crown for use for the patient and develop a plan for intraoral surface treatment for the identified predesigned crown and automated crown inventory management.

Abstract: Methods of fabricating solar cells using UV-curing of light-receiving surfaces of the solar cells, and the resulting solar cells, are described herein. In an example, a method of fabricating a solar cell includes forming a passivating dielectric layer on a light-receiving surface of a silicon substrate. The method also includes forming an anti-reflective coating (ARC) layer below the passivating dielectric layer. The method also includes exposing the ARC layer to ultra-violet (UV) radiation. The method also includes, subsequent to exposing the ARC layer to ultra-violet (UV) radiation, thermally annealing the ARC layer.

Abstract: A binder for an electrode is provided herein. In one example, the electrode may include a current collector, and an electrode coating layer, the electrode coating layer including an electrode active material and a binder, where the binder may comprise an aromatic polyamide-based compound, and the binder may be present at greater than 0 wt % and less than or equal to 30 wt % of the electrode coating layer. In one example, the binder provides stronger cohesion between particles of the electrode active material. Methods and systems are further provided for fabricating the electrode including the binder.

Abstract: In an approach, a processor receives device identification information corresponding to at least one device local to a location of a transaction. A processor receives notification of an infected user. A processor determines that the infected user is associated with the transaction. A processor identifies a second user from the device identification information. A processor sends a notification to the second user.

Abstract: A system includes a content provider serving a first user webpage that displays an external posting link associated with a computer store and a second user webpage of a social networking service. The computer store contains posts each associated with a post select control. A computer server at the content provider is coupled to the computer store and for each of the posts is programmed to receive from a web browser of a computer user a signal indicating activation of the post select control of a selected one of the posts displayed by the first user webpage, automatically link the selected one of the posts to the external posting link, receive from the web browser of the computer user a signal indicating activation of the external posting link, and automatically issue the selected one of the posts to the second user webpage for posting thereon.

Abstract: Devices, systems, and techniques are disclosed for managing electrical stimulation therapy and/or sensing of physiological signals such as brain signals. For example, a system may assist a clinician in identifying one or more electrode combinations for sensing a brain signal. In another example, a user interface may display brain signal information and values of a stimulation parameter at least partially defining electrical stimulation delivered to a patient when the brain signal information was sensed.

Abstract: An implantable vascular access device includes a fluid, a self-sealing cover disposed over the reservoir, and an outlet port configured to mate with a catheter, the outlet port fluidically coupled to the fluid reservoir. One or more sensors coupled to the device are configured to capture physiological data while the device is implanted within a patient. The device also includes a data communications unit configured to receive physiological data from the one or more sensors, obfuscate the physiological data, and transmit the obfuscated physiological data to one or more remote computing devices. The device may also be inductively powered and/or can emit a localization signal in response to wireless interrogation.

Abstract: A doped cathode material for lithium-ion batteries is disclosed. Methods and systems are further provided for doping a cathode material for use in a lithium-ion battery. In one example, the doping may be a dry surface doping process. In some examples, dopants may stabilize a crystal structure of the cathode material and may result in fewer side reactions with an electrolyte as compared to an undoped cathode material. As such, cycling performance and capacity retention may be improved relative to the undoped cathode material. Further, in some examples, the doped cathode material produced with the dry surface doping process may have improved cycling performance and capacity retention relative to a comparable doped cathode material produced with a wet surface doping process.

Abstract: The present technology relates to vascular access devices, systems, and methods configured to monitor a patient's health. In some embodiments, the vascular access device may include a sensing element, and the system of the present technology may be configured to obtain physiological measurements of the patient via the sensing element, determine at least one physiological parameter based on the physiological measurement, compare the at least one physiological parameter to a predetermined threshold, and, based on the comparison, provide an indication of the patient's health.

Abstract: A system for processing trading orders comprises an optimizer module operable to receive a first trading order and a second trading order. The optimizer module is further operable to receive market data associated with at least one market center. The optimizer module is further operable to determine whether to transmit the second trading order to the at least one market center prior to transmitting the first trading order to the at least one market center, the determination based at least in part on the market data.