Patents by Inventor C. Lai

C. Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240096721
    Abstract: An electronic package of which the manufacturing method is to dispose an electronic element on a circuit portion, encapsulate the electronic element with an Ajinomoto build-up film (ABF) used as an encapsulating layer, form a wiring layer on the encapsulating layer, and form a conductive via in the encapsulating layer. Therefore, the wiring layer can be well bonded onto the encapsulating layer as the ABF material is used as the encapsulating layer.
    Type: Application
    Filed: August 28, 2023
    Publication date: March 21, 2024
    Inventors: Chien-Kuang LAI, Andrew C. CHANG, Min-Yao CHEN
  • Patent number: 11912396
    Abstract: An assembly and a method for manufacturing an assembly for transmitting torque to an aircraft actuator. The assembly and method include a torque tube having a longitudinal axis and an end fitting. The ending fitting includes a connector portion and an engagement portion that is inserted into the torque tube. The engagement portion includes a first end adjacent the connector portion, a second end opposite the first end, and a coupling region between the first and second end that includes an outer coupling surface having an outer diameter and a continuous groove formed thereon. The continuous groove includes two axial grooves that extend along the outer coupling surface along the longitudinal axis and a first parallel groove that extends circumferentially about the longitudinal axis along the outer coupling surface that joins the two axial grooves.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: February 27, 2024
    Assignee: HAMILTON SUNDSTRAND CORPORATION
    Inventors: Victor Barger, Joseph M. Bielefeldt, Jude C. Lai, Eric W. Karlen
  • Publication number: 20230228009
    Abstract: A multi-ply fabric is disclosed. The fabric has a top yarn arranged to face an atmosphere and a bottom yarn connected to the top yarn, arranged to contact a surface of a user's body. The bottom yarn has a surface area to volume ratio (SA:V) that is greater than the SA:V of the top yarn. In some embodiments, the bottom yarn has a SA:V that is about 25% to about 50% greater than the SA:V of the top yarn.
    Type: Application
    Filed: January 20, 2023
    Publication date: July 20, 2023
    Inventors: Lawrence S.C. LAI, Francis C.K. LAI
  • Patent number: 11167518
    Abstract: A container that includes a microwave interactive web at least partially overlying and joined to a three-dimensional support, wherein the three-dimensional support may be formed prior to having the microwave interactive web mounted thereto. The three-dimensional support may be a preformed container that is sufficiently rigid and dimensionally stable for use in containing food.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: November 9, 2021
    Assignee: Graphic Packaging International, LLC
    Inventors: Brian R. O'Hagan, Laurence M. C. Lai, Joseph Walsh, William Cox, George Hackel, Neilson Zeng, Michael Shaw, Timothy Henry Bohrer
  • Publication number: 20210299265
    Abstract: The present invention provides a novel method for preparing a cell-binding agent cytotoxic agent conjugate. The method comprises the step of reacting a cell-binding agent with a cytotoxic agent or a cytotoxic agent-linker compound having a reactive group capable of forming a covalent bond with the cell-binding agent at a pH between 4 to 9 in the presence of a buffer solution with high ionic strength, wherein the cell-binding agent comprises a lysine ?-NH2 group that forms a covalent bond with the cytotoxic agent or the cytotoxic agent-linker compound having an amine-reactive group. The cell-binding agent-cytotoxic agent conjugates prepared according to the methods described herein are also included in the present invention.
    Type: Application
    Filed: February 3, 2017
    Publication date: September 30, 2021
    Applicants: IMMUNOGEN, INC., IMMUNOGEN, INC.
    Inventors: Katharine C. Lai, Robert W. Herbst, Scott Alan Hilderbrand
  • Publication number: 20210147067
    Abstract: An assembly and a method for manufacturing an assembly for transmitting torque to an aircraft actuator. The assembly and method include a torque tube having a longitudinal axis and an end fitting. The ending fitting includes a connector portion and an engagement portion that is inserted into the torque tube. The engagement portion includes a first end adjacent the connector portion, a second end opposite the first end, and a coupling region between the first and second end that includes an outer coupling surface having an outer diameter and a continuous groove formed thereon. The continuous groove includes two axial grooves that extend along the outer coupling surface along the longitudinal axis and a first parallel groove that extends circumferentially about the longitudinal axis along the outer coupling surface that joins the two axial grooves.
    Type: Application
    Filed: October 21, 2020
    Publication date: May 20, 2021
    Inventors: Victor Barger, Joseph M. Bielefeldt, Jude C. Lai, Eric W. Karlen
  • Patent number: 10683156
    Abstract: A microwave heating construct comprises a base, a wall extending upwardly around the base for defining a cavity for receiving a food item, and a microwave energy shielding element overlying a lower margin of the wall, the microwave energy shielding element having an upper edge including a substantially incurved portion.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: June 16, 2020
    Assignee: Graphic Packaging International, LLC
    Inventors: Laurence M. C. Lai, Sandra M. Tsontzidis, Bing Liu, Angela Chen Li, Neilson Zeng
  • Publication number: 20190038762
    Abstract: This invention relates to antibody-drug conjugates capable of delivering cytotoxic compounds to cancers expressing the guanylyl cyclase C (GCC) transmembrane cell surface receptor.
    Type: Application
    Filed: February 3, 2017
    Publication date: February 7, 2019
    Applicants: MILLENNIUM PHARMACEUTICALS, INC., IMMUNOGEN, INC.
    Inventors: Ole Petter VEIBY, Ravi V. J. CHARI, John M. LAMBERT, Katharine C. LAI, Robert W. HERBST, Scott A. HILDERBRAND
  • Publication number: 20180230218
    Abstract: MET is a receptor tyrosine kinase found on the surface of tumor cells. The present invention includes anti-MET antibodies, forms and fragments, having superior physical and functional properties; immunoconjugates, compositions, diagnostic reagents, methods for inhibiting growth, therapeutic methods, improved antibodies and cell lines; and polynucleotides, vectors and genetic constructs encoding same.
    Type: Application
    Filed: January 3, 2018
    Publication date: August 16, 2018
    Inventors: Thomas Chittenden, Jutta Deckert, Stuart William Hicks, Katharine C. Lai, Peter U. Park, Lingyun Rui, Daniel J. Tavares, Neeraj Kohli
  • Patent number: 10047122
    Abstract: The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected phophoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 14, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Wenjian Qian, Jung Eun Park, Christopher C. Lai, James A. Kelley, Kyung S. Lee, Terrence R. Burke, Jr.
  • Publication number: 20180193315
    Abstract: Compounds having a structure of Formula (IX): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1-Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 12, 2018
    Inventors: Edward A. Kesicki, Arthur F. Kluge, Michael A. Patane, John H. Van Drie, JR., Ce Wang, Maricel Torrent, Michael L. Curtin, Todd M. Hansen, Rick F. Clark, Robin R. Frey, Zhiqin Ji, Yujia Dai, William J. McClellan, Jane Gong, Gui-dong G. Zhu, Anthony Mastracchio, Michael R. Michaelides, Thomas D. Penning, Chunqiu C. Lai
  • Publication number: 20180169989
    Abstract: A container that includes a microwave interactive web at least partially overlying and joined to a three-dimensional support, wherein the three-dimensional support may be formed prior to having the microwave interactive web mounted thereto. The three-dimensional support may be a preformed container that is sufficiently rigid and dimensionally stable for use in containing food.
    Type: Application
    Filed: February 21, 2018
    Publication date: June 21, 2018
    Inventors: Brian R. O'Hagan, Laurence M.C. Lai, Joseph Walsh, William Cox, George Hackel, Neilson Zeng, Michael Shaw, Timothy Henry Bohrer
  • Patent number: 9944036
    Abstract: A container that includes a microwave interactive web at least partially overlying and joined to a three-dimensional support, wherein the three-dimensional support may be formed prior to having the microwave interactive web mounted thereto. The three-dimensional support may be a preformed container that is sufficiently rigid and dimensionally stable for use in containing food.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: April 17, 2018
    Assignee: Graphic Packaging International, LLC
    Inventors: Brian R. O'Hagan, Laurence M. C. Lai, Joseph Walsh, William Cox, George Hackel, Neilson Zeng, Michael Shaw, Timothy Henry Bohrer
  • Publication number: 20180099880
    Abstract: A method for treating water is provided. The method includes feeding gas through a dielectric barrier discharge (DBD) jet device having an electrode and a ground electrode disposed in water comprising at least one organic toxin derived from a biological organism to generate a cavity in the water, and powering the electrode such that a plasma jet is generated in the cavity. The plasma jet interacts with the water to generate oxidizing agents that oxidize and decompose organic toxins in the water.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 12, 2018
    Inventors: Janis C. LAI, John E. FOSTER
  • Publication number: 20180071262
    Abstract: Compounds having a structure of Formula (IX): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.
    Type: Application
    Filed: October 6, 2017
    Publication date: March 15, 2018
    Applicant: AbbVie Inc.
    Inventors: Edward A. Kesicki, Arthur F. Kluge, Michael A. Patane, John H. Van Drie, JR., Ce Wang, Maricel Torrent, Michael L. Curtin, Todd M. Hansen, Rick F. Clark, Robin R. Frey, Zhiqin Ji, Yujia Dai, William J. McClellan, Jane Gong, Gui-dong G. Zhu, Anthony Mastracchio, Michael R. Michaelides, Thomas D. Penning, Chunqiu C. Lai
  • Publication number: 20170350043
    Abstract: A method of making a multi-ply fabric. The fabric has a top side and a back side with the top side being adjacent to an external environment when the fabric is in use and the back side being adjacent to an object to be cooled when the fabric is in use. The method includes providing a top yarn to form the top side of the fabric and providing a bottom yarn to form the back side of the fabric, with the bottom yarn having a higher SA:V than the top yarn. The two yarns are combined together to form a single fabric, with the top yarn looping through bobbins in the bottom yarn and the bottom yarn looping through bobbins in the top yarn so that the top and bottom yarns are linked and networked to-one-another.
    Type: Application
    Filed: June 5, 2017
    Publication date: December 7, 2017
    Inventor: Lawrence S.C. LAI
  • Patent number: 9764887
    Abstract: A construct for heating a food item in a microwave oven includes a base, a wall extending upwardly from the base, a microwave energy shielding element overlying at least a portion of the wall, and a microwave energy diffusing element circumscribed by the microwave energy shielding element. The microwave energy diffusing element includes a plurality of microwave energy reflective elements within a microwave energy transparent area.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: September 19, 2017
    Assignee: Graphic Packaging International, Inc.
    Inventors: Laurence M. C. Lai, Neilson Zeng, Bing Liu
  • Patent number: 9721307
    Abstract: The disclosed embodiments relate to a system for identifying entities (such as companies) that are associated with members of an online social network. During operation, the system obtains text strings from member records in the online social network, wherein each text string is an identifier for an entity that is associated with a member. The system also obtains connection information specifying connections among members of the online social network, and possibly location information for the members. Finally, the system uses the text strings, the connection information and the location information to identify entities that are associated with members of the online social network.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: August 1, 2017
    Assignee: LinkedIn Corporation
    Inventors: Alex C. Lai, Ke Wang
  • Patent number: D789198
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: June 13, 2017
    Assignee: Keurig Green Mountain, Inc.
    Inventors: Benjamin Ngo, Paul Hammerstrand, Anthony C. Lai, Benjamin Li, Keith Choi
  • Patent number: D792165
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: July 18, 2017
    Assignee: Keurig Green Mountain, Inc.
    Inventors: Peter David Cauwood, Matthew John Maitland, Iain James Sabberton, Keir S. Jackson, Anthony C. Lai, Anthony James Sargeant