Abstract: Systems, methods, and computer-readable media are provided for redundantly storing and authenticating event related video data from one or more cameras using a video recording manager device. Additional copies of event related video data are persisted across various storage devices including any combination of internal camera storage, remote storage, and one or more storage mediums associated with the video recording manager device. The stored video data is augmented with authentication metadata to preserve the authenticity such that the video data is suitable as evidence.

Abstract: A moisture detecting article includes a moisture detection module secured to a garment, intended to contain and hold bodily fluids excreted by an animal. The moisture detection module is connectable to a moisture sensor disposed in the garment to detect when bodily fluid is excreted. If moisture is detected, the moisture sensitive detection module enables one or more signals, alarming the animal and its caretaker. The garment includes a moisture absorbent material, detachable from the garment for disposal of the excretion.

Abstract: Novel wax compositions are provided herein comprising at least about 85 wt. % of linear alpha olefins having a carbon number of at least 18, about 8 wt. % to about 40 wt. % of linear alpha olefins having a carbon number of 20, and about 5 wt. % to about 30 wt. % of linear alpha olefins having a carbon number of at least 30. The present wax compositions yield smooth, one-pour container candle waxes and provide ideal container candle burn performance demonstrated by low sooting behavior and a balanced wax consumption.

Abstract: Embodiments of the present invention provide a centralized for allowing communication and transmission of data between entities and third party entities to securely provide requisitions to users. The system is configured for receiving a requisition request from an entity system, wherein the requisition request is associated with a user, in response to receiving the requisition request, performing one or more data transformations to transform at least a part of data associated with the requisition request, transmitting transformed data associated with the requisition request to an intermediary system, transmitting one or more control signals to the intermediary system to cause the intermediary system to transmit the transformed data associated with the requisition request to one or more third party entities, and determining that the intermediary system received one or more requisitions from the one or more third party entities.

Abstract: Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex.

Abstract: Provided herein are deposition systems utilizing coated grids in an ion deposition process which provide more predictable erosion of the coating rather than erosion of the grid itself. Further, coatings may be utilized in which the coating material does not act as a contaminant to the deposition process, thereby eliminating contamination of the sample surface due to deposition of unwanted grid material. Also provided are methods of refurbishing a coated grid by periodically replacing the coating material thus protecting the grid itself and allowing a grid to be used indefinitely.

Abstract: A system is provided for facilitating access to data stored in a cloud-based storage service. Data associated with a user account is stored at the cloud-based storage service. A portion of the data is associated with a heightened authentication protocol. A request for an application to receive data that is associated with the heightened authentication protocol is received at the cloud-based storage service. In response to the request, the request is authenticated based on the heightened authentication protocol. In response to authenticating the request, permission is granted for the application to receive the data that is associated with the heightened authentication protocol. In response to a locking of the data that is associated with the heightened authentication protocol, an indication that the data is unavailable is sent to the application.

Abstract: Provided herein are compositions and methods for treating T cell exhaustion in a subject, by administering a PTD-MYC fusion protein (e.g., an HIV TAT-MYC fusion protein) or immune cells treated with a PTD-MYC fusion protein. Kits for use in practicing the methods are also provided herein.

Abstract: A system is provided for controlling access to data stored in a cloud-based storage service. A first request is received to access data stored at the cloud-based storage service, the data associated with a user account. The first request is authenticated based on a username and password associated with the user account. A second request is received for a file that is stored in an area associated with a heightened authentication protocol. The heightened authentication protocol is performed to authenticate the second request. In response to authenticating the second request, permission is granted to a temporary strong authentication state. The permission is to access the file that is stored in the area associated with the heightened authentication protocol.

Abstract: A system is provided for controlling access to data stored in a cloud-based storage service. A first request is received to access data stored at the cloud-based storage service, the data associated with a user account. The first request is authenticated based on a username and password associated with the user account. A second request is received for a file that is stored in an area associated with a heightened authentication protocol. The heightened authentication protocol is performed to authenticate the second request. In response to authenticating the second request, permission is granted to a temporary strong authentication state. The permission is to access the file that is stored in the area associated with the heightened authentication protocol.

Abstract: Provided herein are compositions and methods for the cryopreservation of immune cells, such as peripheral blood mononuclear cells (PBMCs) by pre-treating the cells with a PTD-MYC fusion protein (e.g., an HIV TAT-MYC fusion protein) prior to freezing. Kits for practicing the methods are also provided herein.

Abstract: Disclosed herein are phytomedicine analytics for research optimization at scale (PhAROS) methods for discovering and/or optimizing polypharmaceutical medicines, the PhAROS method comprising: analyzing, in a single computational space, data from a plurality of traditional medicine systems (TMS), wherein the analysis uses transcultural dictionaries to allow searches within distinct TMS data sets embodying different epistemologies and terminologies, Wherein the analysis uses data returned by a query to identify new polypharmaceutical and/or optimized polypharmaceutical compositions.

Abstract: Some embodiments include a system comprising: an RF source configured to generate an RF signal; an RF frequency control circuit coupled to the RF source and configured to adjust a frequency of the RF signal; an accelerator structure configured to accelerate a particle beam in response to the RF signal; and control logic configured to: receive a plurality of settings over time for the RF source; adjust the RF signal in response to the settings; and adjust a setpoint of the RF frequency control circuit in response to the settings.

Abstract: The present disclosure relates to the acceleration of hematopoietic compartment reconstitution in a subject in need of hematopoietic stem cell transplantation by administering a composition having a protein transduction domain-MYC (PTD-MYC) fusion protein in combination with hematopoietic stem cell transplantation and to the enhancement of hematopoietic compartment autoreconstitution in a subject in need thereof by administering a composition having a protein transduction domain-MYC (PTD-MYC) fusion protein.

Abstract: The invention relates to 1,2,3,4-substituted quinoline compounds as S1P modulators, pharmaceutical compositions comprising such compounds, and uses thereof in the treatment, alleviation or prevention of diseases or disorders mediated by an S1P receptor.

Abstract: Provided herein are methods and compositions for the treatment of melanoma using anti-tumor immune cells treated with a PTD-MYC fusion protein (e.g., an HIV TAT-MYC fusion protein).

Abstract: The present disclosure relates to the acceleration of hematopoietic compartment reconstitution in a subject in need of hematopoietic stem cell transplantation by administering a composition having a protein transduction domain-MYC (PTD-MYC) fusion protein in combination with hematopoietic stem cell transplantation and to the enhancement of hematopoietic compartment autoreconstitution in a subject in need thereof by administering a composition having a protein transduction domain-MYC (PTD-MYC) fusion protein.

Abstract: The present disclosure relates to the production of red blood cells from hematopoietic stem cells, by differentiating such cells in the presence of a protein that induces cell survival and proliferation.

Abstract: Provided herein are methods and compositions for the treatment of melanoma using anti-tumor immune cells treated with a PTD-MYC fusion protein (e.g., an HIV TAT-MYC fusion protein).

Abstract: Techniques are disclosed for correlating delivery receipt (DLR) messages with short message service (SMS) messages sent in an application-to-person (A2P) manner through a messaging network comprising multiple data centers. SMS and DLR messages are received and stored into a correlator comprising a local and a global storage area. It is then determined whether a received DLR message corresponds to a received SMS message within a local timeout period associated with the received SMS message. When corresponding DLR and SMS messages have been received they are correlated and the DLR message is sent to the sending SMS client. When corresponding DLR and SMS messages have not been received the location of a global storage area of a correlator in a data center where the DLR and SMS messages are intended to be stored is derived.