Abstract: This invention relates to, among other embodiments, methods and apparatus/systems for controlling gases delivery to a patient, such as via a patient interface. Such methods comprising receiving an input relating to either a patient's breathing phase and/or another patient parameter, controlling a flow of gases to be delivered to the patient and the inclusion in said flow of gases of a supplementary gas, wherein the amount of supplementary gas provided to the patient is substantially synchronized with respect to the patient's breathing phase and/or another patient parameter.

Abstract: The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

Abstract: An apparatus for oxygenation and/or CO2 clearance of a patient. The apparatus comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow. The controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with at least two oscillating components. One oscillating component has a frequency based on the heart activity and/or trachea flow of the patient. One oscillating component has a frequency to: promote bulk gas flow movement, or promote mixing.

Abstract: An apparatus or kit for a respiratory support system for delivering humidified gas to a user or patient. The apparatus comprising a humidifier chamber in pneumatic communication with a gases source, an inspiratory conduit in pneumatic communication with the humidifier chamber downstream of the humidifier chamber, a filter that is in pneumatic communication with the inspiratory conduit downstream of the inspiratory conduit, and a patient interface for delivering humidified gas to a user or patient, wherein the patient interface is in pneumatic communication with the filter downstream of the filter, or is configured to be placed in pneumatic communication with the filter downstream of the filter.

Abstract: A user interface convertible between a nasal configuration and an oral configuration. The user interface has a nasal cannula and a mouthpiece. The nasal cannula has a body portion and at least one prong extending from the body portion, the prong being adapted to direct a flow of gas into a nare of a user's nose. The mouthpiece is adapted to engage the mouth of the patient and direct a flow of gas into a user's mouth. In the nasal configuration the prong of the nasal cannula is adapted to direct a flow of gases into a nare of the patient. In the oral configuration, the nasal cannula is engaged with the mouthpiece such that a gases flow is provided to at least the mouth of the user.

Abstract: The present disclosure relates to determining a corrected exhaled gas measurement during high flow respiratory therapy. Measuring exhaled gas concentration during high flow respiratory therapy is difficult and inaccurate due to a phenomenon known as flushing. The high flows delivered to the patient flush the dead space in the conducting airways, which causes a dilution effect that results in underestimated or overestimated exhaled gas measurement depending on the gas composition delivered by the high flow system. This can lead to incorrect clinical measurements and diagnoses. Various algorithms are disclosed herein to account for the dilution effect caused by flushing, allowing for the method of measuring gas concentrations to still be used accurately for clinical measurements.

Abstract: This invention relates to, among other embodiments, methods and apparatus/systems for controlling gases delivery to a patient, such as via a patient interface. Such methods comprising receiving an input relating to either a patient's breathing phase and/or another patient parameter, controlling a flow of gases to be delivered to the patient and the inclusion in said flow of gases of a supplementary gas, wherein the amount of supplementary gas provided to the patient is substantially synchronized with respect to the patient's breathing phase and/or another patient parameter.

Abstract: The present disclosure relates to determining a corrected exhaled gas measurement during high flow respiratory therapy. Measuring exhaled gas concentration during high flow respiratory therapy is difficult and inaccurate due to a phenomenon known as flushing. The high flows delivered to the patient flush the dead space in the conducting airways, which causes a dilution effect that results in underestimated or overestimated exhaled gas measurement depending on the gas composition delivered by the high flow system. This can lead to incorrect clinical measurements and diagnoses. Various algorithms are disclosed herein to account for the dilution effect caused by flushing, allowing for the method of measuring gas concentrations to still be used accurately for clinical measurements.

Abstract: There is disclosed system for oxygenating a patient in relation to anaesthesia using high flow gas delivery. The system has a flow source, and a controller for determining oxygenation requirements of the patient before or during anaesthesia. A method of oxygenating a patient in relation to anaesthesia using high flow gas delivery is also disclosed. The method determines oxygenation requirements of the patient before or during anaesthesia.

Abstract: Nasal cannula assemblies for providing respiratory therapy to patients are provided. A nasal cannula assembly can include a cannula, an optional manifold which may be removable, a gas supply tube, and a securement mechanism. Securement mechanisms can include headgear straps, cheek pads, or an adhesive nose strip. A nasal cannula assembly can also include a lanyard, lanyard clip, and/or lanyard connector to help support the weight of a main gas delivery conduit.

Abstract: There is disclosed system for oxygenating a patient in relation to anaesthesia using high flow gas delivery. The system has a flow source, and a controller for determining oxygenation requirements of the patient before or during anaesthesia. A method of oxygenating a patient in relation to anaesthesia using high flow gas delivery is also disclosed. The method determines oxygenation requirements of the patient before or during anaesthesia.

Abstract: A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit.

Abstract: A mask 100 configured to substantially surround an opening of a patient's airway. The mask has a mask body 101 comprising a filter 103 configured to filter a fluid from a patient facing side of the mask to a non-patient facing side 105 of the mask, wherein the non-patient facing side faces an ambient environment AE. The mask has an interfacing feature 121 configured to, in use, interface with a patient interface 10100, 10100? provided on the patient 10020.

Abstract: Nasal cannula assemblies for providing respiratory therapy to patients are provided. A nasal cannula assembly can include a cannula, an optional manifold which may be removable, a gas supply tube, and a securement mechanism. Securement mechanisms can include headgear straps, cheek pads, or an adhesive nose strip. A nasal cannula assembly can also include a lanyard, lanyard clip, and/or lanyard connector to help support the weight of a main gas delivery conduit.

Abstract: A nasal cannula interface is provided for a respiratory support system configured to receive a breathable gases flow, the nasal cannula interface comprising: a. an inlet to receive the gases flow; b. at least one nasal prong configured to receive the gases flow from the inlet, and to be received in, and to deliver the gases flow to, a nare of the patient. The nasal cannula interface may comprise one or more structural features that are configured to help manage, avoid and/or reduce generation of aerosols by the patient during breathing and/or whilst breathing gases from a respiratory support apparatus.

Abstract: A patient interface for delivery of gas to a patient comprises at least one inspiratory element for directing a flow of gas to a patient airway, at least one expiratory element comprising an expiratory gas flow path for directing expiratory gases from the patient; and at least one gas permeable body in the expiratory gas flow path. Each inspiratory element comprises at least one inspiratory lumen through which said flow of gas is directed. The gas permeable body is configured such that expiratory gases in the expiratory gas flow path are directed through the gas permeable body before exiting the patient interface.

Abstract: A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit.

Abstract: A method of estimating a parameter indicative of respiratory flow of a patient being administered flow therapy, comprising: optionally administering a gas at a flow rate to the patient using a flow therapy apparatus with a patient interface, determin—-ing a terminal pressure in, at or proximate the outlet of the patient interface or in, at or proximate the nares of the patient, determin -ing nasal RTF, determining a nasal flow parameter being or indicative of nasal flow based on the pressure and a nasal RTF, and optionally outputting the nasal flow parameter or parameter derived therefrom.

Abstract: Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.