Abstract: An improved system architecture uses a Generative Adversarial Network (GAN) including a specialized generator neural network to generate multiple resolution output images. The system produces a latent space representation of an input image. The system generates a first output image at a first resolution by providing the latent space representation of the input image as input to a generator neural network comprising an input layer, an output layer, and a plurality of intermediate layers and taking the first output image from an intermediate layer, of the plurality of intermediate layers of the generator neural network. The system generates a second output image at a second resolution different from the first resolution by providing the latent space representation of the input image as input to the generator neural network and taking the second output image from the output layer of the generator neural network.

Abstract: Systems and methods train and apply a specialized encoder neural network for fast and accurate projection into the latent space of a Generative Adversarial Network (GAN). The specialized encoder neural network includes an input layer, a feature extraction layer, and a bottleneck layer positioned after the feature extraction layer. The projection process includes providing an input image to the encoder and producing, by the encoder, a latent space representation of the input image. Producing the latent space representation includes extracting a feature vector from the feature extraction layer, providing the feature vector lo the bottleneck layer as input, and producing the latent space representation as output. The latent space representation produced by the encoder is provided as input to the GAN, which generates an output image based upon the latent space representation.

Abstract: A safety mechanism for a firearm includes a cam selector, a lever, and a trigger. The cam selector comprises a first end, a second end, a top side, and a bottom side. The cam selector comprises a longitudinal slot positioned on the top side of the cam selector. The lever comprises a proximal end and a distal end. The longitudinal slot is configured to receive the lever. The cam selector further comprises a first recess and a second recess on the bottom side of the cam selector. The trigger comprises a first trigger tail portion. In addition to the standard semi-automatic and safe modes, the present invention provides an additional active reset mode in which the cam selector is configured to allow the first trigger tail portion to engage the second recess and be moved down by a cam portion of the second recess when the cam selector rotates.

Abstract: An item recommendation system receives a set of recommendable items and a request to select, from the set of recommendable items, a contrast group. The item recommendation system selects a contrast group from the set of recommendable items by applying a image modification model to the set of recommendable items. The image modification model includes an item selection model configured to determine an unbiased conversion rate for each item of the set of recommendable items and select a recommended item from the set of recommendable items having a greatest unbiased conversion rate. The image modification model includes a contrast group selection model configured to select, for the recommended item, a contrast group comprising the recommended item and one or more contrast items. The item recommendation system transmits the contrast group responsive to the request.

Abstract: A supercontinuum source including a pump source and a supercontinuum generator configured for receiving electromagnetic radiation derived from the pump source and for generating supercontinuum radiation, the supercontinuum generator including a nonlinear microstructured optical fibre having a core region comprising silica. The core region includes a dopant selected to reduce light-induced non-bridging oxygen hole centre loss in the nonlinear microstructured optical fibre.

Abstract: The invention provides compounds of formula (I): where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds and methods of using such compounds to treat respiratory diseases.

Abstract: A supercontinuum source including a pump source and a supercontinuum generator configured for receiving electromagnetic radiation derived from the pump source and for generating supercontinuum radiation, the supercontinuum generator including a nonlinear microstructured optical fibre having a core region comprising silica. The core region includes a dopant selected to reduce light-induced non-bridging oxygen hole centre loss in the nonlinear microstructured optical fibre.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that modify digital images via scene-based editing using image understanding facilitated by artificial intelligence. For example, in one or more embodiments the disclosed systems utilize generative machine learning models to create modified digital images portraying human subjects. In particular, the disclosed systems generate modified digital images by performing infill modifications to complete a digital image or human inpainting for portions of a digital image that portrays a human. Moreover, in some embodiments, the disclosed systems perform reposing of subjects portrayed within a digital image to generate modified digital images. In addition, the disclosed systems in some embodiments perform facial expression transfer and facial expression animations to generate modified digital images or animations.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that modify digital images via scene-based editing using image understanding facilitated by artificial intelligence. For example, in one or more embodiments the disclosed systems utilize generative machine learning models to create modified digital images portraying human subjects. In particular, the disclosed systems generate modified digital images by performing infill modifications to complete a digital image or human inpainting for portions of a digital image that portrays a human. Moreover, in some embodiments, the disclosed systems perform reposing of subjects portrayed within a digital image to generate modified digital images. In addition, the disclosed systems in some embodiments perform facial expression transfer and facial expression animations to generate modified digital images or animations.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for generating painted digital images utilizing an intelligent painting process that includes progressive layering, sequential brushstroke guidance, and/or brushstroke regularization. For example, the disclosed systems utilize an image painting model to perform progressive layering to generate and apply digital brushstrokes in a progressive fashion for different layers associated with a background canvas and foreground objects. In addition, the disclosed systems utilize sequential brushstroke guidance to generate painted foreground objects by sequentially shifting through attention windows for regions of interest in a target digital image. Furthermore, the disclosed systems utilize brushstroke regularization to generate and apply an efficient brushstroke sequence to generate a painted digital image.

Abstract: The present disclosure describes systems, methods, and non-transitory computer readable media for detecting user interactions to edit a digital image from a client device and modify the digital image for the client device by using a web-based intermediary that modifies a latent vector of the digital image and an image modification neural network to generate a modified digital image from the modified latent vector. In response to user interaction to modify a digital image, for instance, the disclosed systems modify a latent vector extracted from the digital image to reflect the requested modification. The disclosed systems further use a latent vector stream renderer (as an intermediary device) to generate an image delta that indicates a difference between the digital image and the modified digital image. The disclosed systems then provide the image delta as part of a digital stream to a client device to quickly render the modified digital image.

Abstract: Systems and methods dynamically adjust an available range for editing an attribute in an image. An image editing system computes a metric for an attribute in an input image as a function of a latent space representation of the input image and a filtering vector for editing the input image. The image editing system compares the metric to a threshold. If the metric exceeds the threshold, then the image editing system selects a first range for editing the attribute in the input image. If the metric does not exceed the threshold, a second range is selected. The image editing system causes display of a user interface for editing the input image comprising an interface element for editing the attribute within the selected range.

Abstract: Provided herein are compounds of formula (I): and pharmaceutically-acceptable salts thereof, where A, W, X, Y and Z are defined in the specification. The compounds of formula (I) and pharmaceutically-acceptable salts thereof are Janus kinase (JAK) inhibitors. Also provided herein are pharmaceutical compositions comprising such compounds; and methods of using such compounds to treat, e.g., inflammatory and fibrotic diseases, including respiratory diseases.

Abstract: A cabling system for extending electronic signals between devices is disclosed. The cabling system includes an extension cable connecting a female source connector and a destination connecter. The female source connector is housed within a headshell that is configured to mount to a wallplate, a table insert, or a rack panel within meeting and conference locations.

Abstract: An improved system architecture uses a pipeline including a Generative Adversarial Network (GAN) including a generator neural network and a discriminator neural network to generate an image. An input image in a first domain and information about a target domain are obtained. The domains correspond to image styles. An initial latent space representation of the input image is produced by encoding the input image. An initial output image is generated by processing the initial latent space representation with the generator neural network. Using the discriminator neural network, a score is computed indicating whether the initial output image is in the target domain. A loss is computed based on the computed score. The loss is minimized to compute an updated latent space representation. The updated latent space representation is processed with the generator neural network to generate an output image in the target domain.

Abstract: The invention provides compounds of formula (I): which contain a 4-membered heterocyclic amide, where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: Systems and methods generate a filtering function for editing an image with reduced attribute correlation. An image editing system groups training data into bins according to a distribution of a target attribute. For each bin, the system samples a subset of the training data based on a pre-determined target distribution of a set of additional attributes in the training data. The system identifies a direction in the sampled training data corresponding to the distribution of the target attribute to generate a filtering vector for modifying the target attribute in an input image, obtains a latent space representation of an input image, applies the filtering vector to the latent space representation of the input image to generate a filtered latent space representation of the input image, and provides the filtered latent space representation as input to a neural network to generate an output image with a modification to the target attribute.

Abstract: The present disclosure describes systems, methods, and non-transitory computer readable media for detecting user interactions to edit a digital image from a client device and modify the digital image for the client device by using a web-based intermediary that modifies a latent vector of the digital image and an image modification neural network to generate a modified digital image from the modified latent vector. In response to user interaction to modify a digital image, for instance, the disclosed systems modify a latent vector extracted from the digital image to reflect the requested modification. The disclosed systems further use a latent vector stream renderer (as an intermediary device) to generate an image delta that indicates a difference between the digital image and the modified digital image. The disclosed systems then provide the image delta as part of a digital stream to a client device to quickly render the modified digital image.

Abstract: The present invention relates, in part, to methods, systems and processes for large-scale purification of mRNA using a filtering centrifuge operating at lower gravitational forces. The invention also relates to compositions of purified mRNA and uses thereof.