Patents by Inventor Camilo Colaco

Camilo Colaco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
    Patent number: 6313102
    Abstract: The present invention encompasses methods of increasing stability of biological substances during drying and the dried compositions derived therefrom. The compositions have improved storage stability.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: November 6, 2001
    Assignee: Quardrant Holdings Cambridge, Ltd.
    Inventors: Camilo Colaco, Bruce J. Roser, Shevanti Sen
  • Solid dose delivery vehicle and methods of making same
    Patent number: 6290991
    Abstract: The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and shaped for penetrating the epidermis. The delivery vehicle further comprises a stabilizing polyol glass loaded with the bioactive material and capable of releasing the bioactive material in situ. The present invention further includes methods of making and using the solid dose delivery vehicle of the invention.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: September 18, 2001
    Assignee: Quandrant Holdings Cambridge Limited
    Inventors: Bruce J. Roser, Jaap Kampinga, Camilo Colaco, Julian Blair
  • Use of Maillard reaction inhibitors for the treatment of amyloidosis-based disease
    Patent number: 6034080
    Abstract: Inhibitors of the Maillard reaction are useful in the treatment or prophylaxis of amyloidosis-based disease, particularly Alzheimer's disease. Particular examples include aminoguanidine and amphotericin B.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: March 7, 2000
    Assignee: Quadrant Holdings Cambridge Limited
    Inventors: Camilo Colaco, Bruce Joseph Roser
  • Oral solid dosage forms, methods of making same and compositions thereof
    Patent number: 5958455
    Abstract: Methods of making tablets of a variety of physical forms are described. The tablets can be made into a wide variety of formulations. The invention further provides methods of making crystalline and amorphous anhydrous trehalose for use in formulating tablets suitable for use in dispensing pharmaceutical agents.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: September 28, 1999
    Assignee: Quadrant Holdings Cambridge Ltd
    Inventors: Bruce J. Roser, Julian Blair, Camilo Colaco, Ross Henry Morris Hatley
  • Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
    Patent number: 5955448
    Abstract: The present invention encompasses methods of increasing stability of biological substances during drying and the dried compositions derived therefrom. The compositions have improved storage stability.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: September 21, 1999
    Assignee: Quadrant Holdings Cambridge Limited
    Inventors: Camilo Colaco, Bruce J. Roser, Shevanti Sen
  • Use of maillard reaction inhibitors for the treatment of amyloidosis-based disease
    Patent number: 5891873
    Abstract: Inhibitors of the Maillard reaction are useful in the treatment or prophylaxis of amyloidosis-based disease, particularly Alzheimer's disease. Particular examples include aminoguanidine and amphotericin B.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: April 6, 1999
    Assignee: Quadrant Holdings Cambridge Limited
    Inventors: Camilo Colaco, Bruce Joseph Roser
  • Method of preserving agarose gel structure during dehydration by adding a non-reducing glycoside of a straight-chain sugar alcohol
    Patent number: 5621094
    Abstract: A method of preserving delicate biological substances or organic compounds (a) in a dry state and/or (b) at elevated temperatures and/or (c) under irradiation comprises incorporating in a system containing the said substances or compounds, a sugar or a sugar derivative selected from (i) a non-reducing glycoside of a polyhydroxy compound selected from sugar alcohols and other straight chain polyalcohols, or (ii) a non-reducing oligosaccharide selected from raffinose, stachyose and melezitose. In particular, methods for preserving dehydrated agarose gels comprising adding lactitol or glucopyranosyl-mannitol or glucopyranosyl-sorbitol to the gel during formation and prior to dehydration are disclosed.
    Type: Grant
    Filed: June 8, 1994
    Date of Patent: April 15, 1997
    Assignee: Quadrant Holdings Cambridge Limited
    Inventors: Bruce J. Roser, Camilo Colaco