Abstract: Current interfaces for displaying information about items appearing in videos are obtrusive and counterintuitive. They also rely on annotations, or metadata tags, added by hand to the frames in the video, limiting their ability to display information about items in the videos. In contrast, examples of the systems disclosed here use neural networks to identify items appearing on- and off-screen in response to intuitive user voice queries, touchscreen taps, and/or cursor movements. These systems display information about the on- and off-screen items dynamically and unobtrusively to avoid disrupting the viewing experience.

Abstract: In a display assistant device, a speaker is mounted in a waveguide structure which is at least partially disposed beneath a display screen. The waveguide structure is mounted in an exterior housing which includes speaker grills distributed on a plurality of surfaces of the exterior housing, permitting sound waves from the speaker to be projected outside the exterior housing. A cover structure is disposed on top of the waveguide structure to conceal the waveguide structure and speaker within the exterior housing. The cover structure has a tilted bottom surface configured to be suspended above the waveguide structure and to be separated by a first space. Sound waves projected from an upper portion of the speaker are reflected by the tilted bottom surface and are guided through the first space to exit the device from a speaker grill portion located on a rear side of the exterior housing.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for receiving, from one of two or more sensors of a device that independently determine whether an aircraft takeoff has likely occurred, an indication that the aircraft takeoff has likely occurred; activating, based on receiving the indication that the aircraft takeoff has likely occurred, an airplane mode of the device; receiving, while the device is in the airplane mode and from one of two or more other sensors of the device that independently determine that an aircraft flight is likely not occurring, an indication that the aircraft flight is likely not occurring; and deactivating, based on receiving the indication that the aircraft flight is likely not occurring, the airplane mode of the device. The indication that the aircraft takeoff has likely occurred may include acceleration data indicating an acceleration of the device in three dimensions.

Abstract: The disclosure relates to immune cells comprising a dual receptor system responsive to loss of heterozygosity in a target cell, and methods of making and using same. The first receptor comprises activator receptor specific to a HER2 antigen, and the second receptor comprises an inhibitory receptor specific to an antigen lost in cancer but not wild type cells, that inhibits activation of the immune cells by the first receptor.

Abstract: Systems and methods of a monitoring node to assist an air navigation service provider (ANSP) in the design of an airspace. The monitoring node collects flight data and performs flight simulations for a large geographic region that is outside of the airspace. The monitoring node receives flight data collected by the ANSP for the airspace. The monitoring node supplements their flight data with the data received from the ANSP and performs flight simulations and generates flight plans for the airspace. The flight simulations and flight plans are transmitted to the ANSP which are then used by the ANSP to design the airspace.

Abstract: The disclosure relates to immune cells comprising systems of two engineered receptors each having a ligand binding domain, collectively designed to target cells identified by loss of heterozygosity and used to treat a disease or disorder, for example, cancer. The disclosure provides immune cells expressing two engineered receptors, methods of making same, and polynucleotides and vectors encoding same.

Abstract: The disclosure relates to fusion proteins comprising a tBID polypeptide and a steroid hormone receptor domain, and methods of using same to induce apoptosis in cells.

Abstract: The disclosure provides immune cells comprising a first activator receptor and a second inhibitory receptor, and methods of making and using same for the treatment of cancer.

Abstract: The disclosure provides immune cells comprising a first activator receptor specific to mesothelin and a second inhibitory receptor specific to a ligand that has been lost in a mesothelin-positive cancer cell, and methods of making and using same for the treatment of cancer.

Abstract: The disclosure relates to immune cells comprising a dual receptor system responsive to loss of heterozygosity in a target cell, and methods of making and using same. The first receptor comprises activator receptor specific to a HER2 antigen, and the second receptor comprises an inhibitory receptor specific to an antigen lost in cancer but not wild type cells, that inhibits activation of the immune cells by the first receptor.

Abstract: The disclosure provides immune cells comprising a first activator receptor and a second inhibitory receptor, and methods of making and using same for the treatment of cancer.

Abstract: Various embodiments also include a computer-implemented method comprising determining a communications mode for a plurality of consoles operating within a vehicle, based on the determined communications mode, initiating an in-vehicle communication between a set of consoles included in the plurality of consoles, where the set of consoles includes at least a first console and a second console, in response to the in-vehicle communication, causing each of the set of consoles to attenuate volumes of a set of content items playing on each of the set of consoles, and receiving a speech signal generated by a first user of the set of consoles, and causing the set of consoles to reproduce the speech signal.

Abstract: In various embodiments, a computer-implemented method comprises receiving a set of two or more first media signals from two or more consoles included in a vehicle, where each of the two or more consoles are included in a common communication session, combining the set of two or more first media signals to generate a composite media signal, transmitting, via a communication link, the composite media signal to a remote destination, receiving, via the communication link, a remote media signal from the remote destination, and causing the two or more first media signals and the remote media signal to be reproduced at the two or more consoles.

Abstract: The disclosure provides immune cells comprising a first activator receptor specific to CEA, and a second inhibitory receptor, and methods of making and using same for the treatment of cancer.

Abstract: One embodiment includes a method for offering a protection policy for a mobile device, the method comprising the steps of providing an application, conducting a test of the mobile device, calculating the risk of protecting the mobile device, and offering an protection policy. The application is configured to operate on the mobile device and to test at least one function of the mobile device. The test is conducted by the application and verifies at least one function of the mobile device through the application. The risk of protecting the mobile device is based upon at least one result of the test. The protection policy for the mobile device is based upon the calculated risk, has a cost, and is offered for purchase to a user of the mobile device.

Abstract: In a display assistant device, a speaker is mounted in a waveguide structure which is at least partially disposed beneath a display screen. The waveguide structure is mounted in an exterior housing which includes speaker grills distributed on a plurality of surfaces of the exterior housing, permitting sound waves from the speaker to be projected outside the exterior housing. A cover structure is disposed on top of the waveguide structure to conceal the waveguide structure and speaker within the exterior housing. The cover structure has a tilted bottom surface configured to be suspended above the waveguide structure and to be separated by a first space. Sound waves projected from an upper portion of the speaker are reflected by the tilted bottom surface and are guided through the first space to exit the device from a speaker grill portion located on a rear side of the exterior housing.

Abstract: In one aspect the invention provides a method of operating a time of flight camera which includes the steps of capturing a sequence of time of flight camera data frames using a set of step frequency modulation signals to provide a time of flight camera data set, then completing a spectral analysis of the dataset which identifies frequency and phase value pairs indicative of the range of the camera to an object represented in the data frames. Next an estimated camera range value to an object represented in the data frames is determined using the frequency value, then a corrected camera range value is determined using the estimated camera range value and the phase value. A camera output is then provided which identifies the corrected range values of at least one object represented in the data frames of the dataset.

Abstract: The disclosure provides immune cells comprising a first activator receptor specific to mesothelin and a second inhibitory receptor specific to a ligand that has been lost in a mesothelin-positive cancer cell, and methods of making and using same for the treatment of cancer.

Abstract: The disclosure provides immune cells comprising a first activator receptor and a second inhibitory receptor, and methods of making and using same for the treatment of cancer.

Abstract: Provided are polynucleotides comprising nucleic acid sequences encoding chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are vectors and immune cells comprising said polynucleotides.