Abstract: A multinotch filter for selectively removing target ions with a plurality of specific mass-to-charge ratios from an ion beam is disclosed. The multinotch filter uses a quadrupole and a power supply for generating rf voltages in the quadrupole. The quadrupole has two pairs of parallel electrodes. Each pair has two parallel, oppositely facing electrodes. The rf voltages generated by the power supply includes a rf quadrupole frequency component and at least a first excision frequency component and a second excision frequency component. The rf quadrupole frequency component is applied to the electrodes such that within each pair the two oppositely facing electrodes with respect to the rf quadrupole frequency component are equal in potential and the two pairs are 180.degree. out of phase. With respect to the first excision frequency component, the oppositely facing electrodes within one pair are 180.degree. out of phase with each other.

Abstract: Disclosed are pH dyes containing a suitable compatible substituent which permits binding of the dye to a solid support. Also disclosed are methods for synthesizing such dyes prior to their coupling to the solid supports.

Abstract: A method and apparatus for analyzing ions by determining times of flight include establishing an encoded sequence for launching packets of ions from a source region toward a detector. The encoded sequence is one in which the high-mass ions of a leading packet will be passed by the low-mass ions of a trailing packet. Thus, a high efficiency time-of-flight mass spectrometer is formed. The ions of each packet are acted upon to bunch the ions of the packet, thereby compensating for initial space and/or velocity distributions of ions in the launching of the packet. The times of arrival of the ions are determined at the detector to obtain a signal of overlapping spectra corresponding to the overlapping launched packets. A correlation between the overlapping spectra and the encoded launch sequence is employed to derive a single non-overlapped spectrum.

Abstract: Disclosed are pH dyes containing a suitable compatible substituent which permits binding of the dye to a solid support. Also disclosed are methods for synthesizing such dyes prior to their coupling to the solid supports.

Abstract: A system for accurate and precise measurements of analyte(s) in a system. The measurement system comprises piezoelectric surface wave sample devices, at least one piezoelectric surface wave reference device, and the measurement instrument.

Abstract: A mass biosensor method provides enhanced quantification of analyte concentrations in a sample. In a direct approach, an analyte is derivatized to form an analyte chelate and then specifically bound to a sensor. In an indirect approach, a complement of the analyte is derivatized to form a complement chelate which is then bound to a sensor. In a direct/indirect hybrid approach, an analog of the analyte is derivatized to form an analog chelate that is bound to a sensor in competition with the sample analyte. In all three approaches, mass measurements taken as the ligand chelate attaches to the sensor permit the concentration of the analyte in the sample to be calculated. Once measurement is completed, a dissociation treatment is applied to dissociate the derivatized species from the sensor so that the sensor can be reused. The effects of the dissociation treatment can be monitored using phosphorescence detection.

Abstract: A sensor (11, 12, 13, 15) suitable for use as a viscosity sensor, a chemically selective sensor, or a chemically specific sensor. The sensor (11, 12, 13, 15) is a surface transverse wave (STW) device that, for solute concentration measurements, includes a binding layer (18) selected to bind to the solute to be measured. This binding layer (18) can be an antibody so that the sensor detects a particular antigen.

Abstract: In a multi-jointed robot, position controllers are located at each of the joints of the robot and are interconnected by a unitary bus. The bus carries a loosely-regulated voltage to all of the controllers and also includes data conductors connected to the controllers for disseminating position commands which are time-division multiplexed.

Abstract: A forensic sample and tracking system includes a computer system which operates a data base and a read/write station. The assignment of an identifier in the data base and an identification code to be printed on a sample bottle label are coordinated by the computer. An identification code can then be read for verification after it is written. This permits automated verifying of identification codes in a heretofore unavailable manner. The read/write station makes use of an inexpensive, reliable and compact thermal ink jet print head so that a field computer and read/write station can be taken to sample collection sites. The effective linear resolution of the identification code is enhanced using a two-track bar code.

Abstract: Disclosed is a method and device for automatically and instantaneously computing and displaying with high precision the flow rate of thermoplastic samples run in an extrusion plastometer in accordance with American Society of Testing Materials (ASTM) Method D1238. The method and device comprise using a microcomputer and related circuitry to monitor and control the measurement process and subsequently compute the resulting flow rate.