Abstract: This disclosure relates to an interface between an engine block and a cylinder head. The interface includes a ferrule that accommodates relative movement between the cylinder head and the engine block while maintaining sealing of fluid passages that extend between the cylinder head and the engine block. The interface thus forms a fluid passage seal assembly.

Abstract: Aspects of the subject matter described herein relate to predicting phenotypes. In aspects, a probabilistic predictor is used to summarize a relationship between a set of biological predictors and a phenotype. The probabilistic predictor may use a function that is selected based on the type of the phenotype (e.g., binary, multi-state, or continuous). The probabilistic predictor may use genetic and/or epigenetic information. The probabilistic predictor may be trained on a portion of the data in conjunction with predicting phenotypes in another portion of the data. The probabilistic predictor may be used for various analyses including genome-wide association analysis and gene-set enrichment analysis.