Patents by Inventor Carlos Fernandez-Catalan

Carlos Fernandez-Catalan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline TNF-?-converting enzyme and uses thereof
    Patent number: 6842704
    Abstract: A tumor necrosis factor-? converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.
    Type: Grant
    Filed: February 4, 1999
    Date of Patent: January 11, 2005
    Assignees: Immunex Corporation, Max-Planck-Institute for Biochemistry, Wyeth
    Inventors: Roy A. Black, Raymond James Paxton, Wolfram Bode, Klaus Maskos, Carlos Fernandez-Catalan, James Ming Chen, Jeremy Ian Levin
  • Crystalline TNF-alpha-converting enzyme and uses thereof
    Publication number: 20040265983
    Abstract: A tumor necrosis factor-&agr; converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.
    Type: Application
    Filed: February 24, 2004
    Publication date: December 30, 2004
    Applicants: IMMUNEX CORPORATION; MAX-PLANCK-INSTITUTE FOR BIOCHEMISTRY, WYETH
    Inventors: Roy A. Black, Raymond James Paxton, Wolfram Bode, Klaus Maskos, Carlos Fernandez-Catalan, James Ming Chen, Jeremy Ian Levin
  • Crystalline TNF-alpha-converting enzyme and uses thereof
    Publication number: 20030004651
    Abstract: A tumor necrosis factor-&agr; converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.
    Type: Application
    Filed: September 24, 2001
    Publication date: January 2, 2003
    Inventors: Roy A. Black, Raymond James Paxton, Wolfram Bode, Klaus Maskos, Carlos Fernandez-Catalan, James Ming Chen, Jeremy Ian Levin
  • Structural analysis of the calpains as procedures for the development of inhibitors
    Publication number: 20020132333
    Abstract: The invention provides spatial structures and crystal forms of polypeptides comprising at least one subdomain of a protein from the family of proteins that includes calcium-activated cystein proteinases (calpains). Also provided are methods of preparing these crystal forms, and methods of modeling calpains using the coordinates derived from the disclosed crystal forms. The invention further provides compounds that act as ligands for calpains, methods for identifying such ligands, and methods for using such ligands as inhibitors or activators of calpain activity.
    Type: Application
    Filed: December 14, 2000
    Publication date: September 19, 2002
    Inventors: Stefan Strobl, Carlos Fernandez-Catalan, Wolfram Bode, Robert Huber, Koichi Suzuki
  • CRYSTALLINE TNF-ALPHA-CONVERTING ENZYNE AND USES THEREOF
    Publication number: 20020081692
    Abstract: A tumor necrosis factor-&agr; converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.
    Type: Application
    Filed: February 4, 1999
    Publication date: June 27, 2002
    Inventors: ROY A. BLACK, RAYMOND JAMES PAXTON, WOLFRAM BODE, KLAUS MASKOS, CARLOS FERNANDEZ-CATALAN, JAMES MING CHEN, JEREMY IAN LEVIN