Patents by Inventor Carlos J. Bosques

Carlos J. Bosques has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
    Publication number: 20220033499
    Abstract: The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
    Type: Application
    Filed: August 20, 2021
    Publication date: February 3, 2022
    Inventors: Carlos J. Bosques, James S. Huston, Jonathan C. Lansing, Leona E. Ling, James Meador, III, Daniel Ortiz, Laura Rutitzky
  • Engineered Fc constructs
    Patent number: 11220531
    Abstract: The present disclosure relates to engineered IgG Fc constructs and uses thereof.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: January 11, 2022
    Assignee: Janssen Biotech, Inc.
    Inventors: Carlos J. Bosques, Jonathan C. Lansing, Daniel Ortiz
  • Compositions and methods related to engineered Fc constructs
    Patent number: 11155640
    Abstract: The present invention relates to engineered IgG Fc constructs and uses thereof.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: October 26, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: Carlos J. Bosques, Jonathan C. Lansing, Daniel Ortiz, Laura Rutitzky, Nathaniel J. Washburn
  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS
    Publication number: 20210317227
    Abstract: The present disclosure relates to compositions and methods of engineered Fc-antigen binding domain constructs, where the Fc-antigen binding domain constructs include at least two Fc domains and at least one antigen binding domain.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 14, 2021
    Inventors: Jonathan C. Lansing, Daniel Ortiz, Carlos J. Bosques
  • Compositions and methods related to engineered Fc constructs
    Patent number: 11124573
    Abstract: The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: September 21, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: Carlos J. Bosques, James S. Huston, Jonathan C. Lansing, Leona E. Ling, James Meador, III, Daniel Ortiz, Laura Rutitzky
  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
    Publication number: 20210221917
    Abstract: The present disclosure relates to compositions and methods of engineered IgG Fc constructs, wherein the Fc constructs include one or more Fc domains.
    Type: Application
    Filed: May 23, 2017
    Publication date: July 22, 2021
    Inventors: Jonathan C. Lansing, Carlos J. Bosques, Daniel Ortiz
  • Methods and Compositions for the Diagnosis and Treatment of Kawasaki Disease
    Publication number: 20210116462
    Abstract: The present invention relates to the determination of levels or expression of particular biomarkers in biological samples which can be utilized to diagnose, prognose, and treat Kawasaki disease in subjects, and further to select subjects who would benefit from a Kawasaki disease therapy other than, or in addition to, IVIG treatment. Accordingly, the present invention encompasses methods and compositions that utilize these biomarkers for the diagnosis, prognosis, and treatment of Kawasaki disease.
    Type: Application
    Filed: April 6, 2020
    Publication date: April 22, 2021
    Inventors: Dorota A. Bulik, Carlos J. Bosques, Jay Duffner, Leona E. Ling, Hetal Sarvaiya
  • Methods Related to Alemtuzumab
    Publication number: 20200354465
    Abstract: The present invention relates to the characterization and production of alemtuzumab.
    Type: Application
    Filed: April 3, 2020
    Publication date: November 12, 2020
    Inventors: John Robblee, Brian Edward Collins, Ganesh Kaundinya, Carlos J. Bosques
  • Methods For The Treatment Of Neurodegeneration
    Publication number: 20200055921
    Abstract: The invention encompasses the discovery that Fc-containing polypeptides that include branched glycans and that are sialylated on the branched glycan (e.g., on an ? 1,3 and/or ? 1,6 arm in the Fc region's N-linked glycosylation site), with, e.g., a NeuA-? 2,6-Gal or NeuAc-? 2,3-Gal terminal linkage, are useful in treating neurodegeneration, e.g., in the treatment of neurodegenerative diseases such as Alzheimer's Disease. The present disclosure provides, in pert, methods for treating neurodegeneration or neurodegenerative diseases by administering compositions containing such Fc-containing polypeptides as well as methods for evaluating, identifying, and/or producing (e.g., manufacturing) such polypeptides for the treatment of neurodegeneration.
    Type: Application
    Filed: November 1, 2019
    Publication date: February 20, 2020
    Inventors: Thomas E. Prod`Homme, Leona E. Ling, Carlos J. Bosques, Anthony Manning, Ganesh Kaundinya
  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED FC-ANTIGEN BINDING DOMAIN CONSTRUCTS
    Publication number: 20200040084
    Abstract: The present disclosure relates to compositions and methods of engineered Fc-antigen binding domain constructs, where the Fc-antigen binding domain constructs include at least two Fc domains and at least one antigen binding domain.
    Type: Application
    Filed: January 5, 2018
    Publication date: February 6, 2020
    Inventors: Jonathan C. Lansing, Daniel Ortiz, Carlos J. Bosques
  • Compositions and Methods Related to Engineered Fc Constructs
    Publication number: 20190345206
    Abstract: The present disclosure relates to engineered IgG Fc constructs and uses thereof.
    Type: Application
    Filed: January 5, 2018
    Publication date: November 14, 2019
    Inventors: Carlos J. Bosques, Jonathan C. Lansing, Daniel Ortiz
  • Methods for the treatment of neurodegeneration
    Patent number: 10464996
    Abstract: The invention encompasses the discovery that Fc-containing polypeptides that include branched glycans and that are sialylated on the branched glycan (e.g., on an ? 1,3 and/or ? 1,6 arm in the Fc region's N-linked glycosylation site), with, e.g., a NeuAc-? 2,6-Gal or NeuAc-? 2,3-Gal terminal linkage, are useful in treating neurodegeneration, e.g., in the treatment of neurodegenerative diseases such as Alzheimer's Disease. The present disclosure provides, in part, methods for treating neurodegeneration or neurodegenerative diseases by administering compositions containing such Fc-containing polypeptides as well as methods for evaluating, identifying, and/or producing (e.g., manufacturing) such polypeptides for the treatment of neurodegeneration.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: November 5, 2019
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Thomas E. Prod'Homme, Leona E. Ling, Carlos J. Bosques, Anthony Manning, Ganesh Kaundinya
  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
    Publication number: 20190284305
    Abstract: The present invention relates to engineered IgG Fc constructs and uses thereof.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 19, 2019
    Inventors: Carlos J. Bosques, Jonathan C. Lansing, Daniel Ortiz, Laura Rutitzky, Nathaniel J. Washburn
  • Modified glycoproteins
    Patent number: 10377832
    Abstract: Modified glycoproteins, and methods of making and using such modified glycoproteins, are described.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: August 13, 2019
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Nathaniel Washburn, James Meador, III, Carlos J. Bosques, Dorota A. Bulik, Naveen Bhatnagar, Julia Brown, Lynn Markowitz, Sathya Prabbhakar
  • Modified glycoproteins
    Patent number: 10377809
    Abstract: Sulfated glycoproteins, and methods of making and using such sulfated glycoproteins, are described.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: August 13, 2019
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Dorota A. Bulik, Carlos J. Bosques, Brian Edward Collins, Maurice Gaston Hains, Nathaniel J. Washburn, James Meador, Sean Smith, Naveen Bhatnagar
  • COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
    Publication number: 20190225688
    Abstract: The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 25, 2019
    Inventors: Carlos J. Bosques, James S. Huston, Jonathan C. Lansing, Leona E. Ling, James Meador, III, Daniel Ortiz, Laura Rutitzky
  • Multi-dimensional chromatographic methods for separating N-glycans
    Patent number: 10317410
    Abstract: A multi-dimensional chromatographic method for the separation of N-glycans. The method comprises providing a glycan preparation that includes at least one negatively charged N-glycan. The glycan preparation is then separated by anion-exchange chromatography and at least one secondary chromatographic technique.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: June 11, 2019
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Ian Christopher Parsons, Ting Zheng, Nur Sibel Gunay, Carlos J. Bosques
  • Compositions and methods related to engineered Fc constructs
    Patent number: 10239944
    Abstract: The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: March 26, 2019
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Carlos J. Bosques, James S. Huston, Jonathan C. Lansing, Leona E. Ling, James Meador, III, Daniel Ortiz, Laura Rutitzky
  • METHODS RELATED TO ADALIMUMAB
    Publication number: 20190077857
    Abstract: The present invention relates to the characterization and production of adalimumab.
    Type: Application
    Filed: May 9, 2018
    Publication date: March 14, 2019
    Inventors: John Robblee, Brian Edward Collins, Ganesh Kaundinya, Carlos J. Bosques
  • METHODS OF EVALUATING AND MAKING BIOLOGICS
    Publication number: 20190079101
    Abstract: Methods of making and evaluating biologic therapeutic products are disclosed.
    Type: Application
    Filed: April 9, 2018
    Publication date: March 14, 2019
    Inventors: John Robblee, Brian Edward Collins, Ganesh Kaundinya, Carlos J. Bosques